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Volumn 58, Issue 2, 2000, Pages 421-430

Kinetic analysis of agonist-induced down-regulation of the β2- adrenergic receptor in BEAS-2B cells reveals high- and low-affinity components

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; DOBUTAMINE; EPHEDRINE; FENOTEROL;

EID: 0033943304     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.58.2.421     Document Type: Article
Times cited : (25)

References (23)
  • 1
    • 0343102305 scopus 로고    scopus 로고
    • Evidence for agonist-specific states of receptor
    • Hoyer D, Humphrey PPA, Leff P, Shankley NP and Trist DG eds IUPHAR Media, London, in press
    • Blevins T, Krumins A and Barber R (2000) Evidence for agonist-specific states of receptor, in Receptor Mechanisms: Principles of Agonism (Hoyer D, Humphrey PPA, Leff P, Shankley NP and Trist DG eds) IUPHAR Media, London, in press.
    • (2000) Receptor Mechanisms: Principles of Agonism
    • Blevins, T.1    Krumins, A.2    Barber, R.3
  • 3
    • 0001205470 scopus 로고    scopus 로고
    • Partial agonists and G protein-coupled receptor desensitization
    • Clark RB, Knoll BJ and Barber R (1999) Partial agonists and G protein-coupled receptor desensitization. Trends Pharm Sci 20:279-286.
    • (1999) Trends Pharm Sci , vol.20 , pp. 279-286
    • Clark, R.B.1    Knoll, B.J.2    Barber, R.3
  • 4
    • 0026513232 scopus 로고
    • From ligand binding to gene expression: New insights into the regulation of G-protein-coupled receptors
    • Collins S, Caron MG and Lefkowitz RJ (1992) From ligand binding to gene expression: New insights into the regulation of G-protein-coupled receptors. Trends Biochem Sci 17:37-39.
    • (1992) Trends Biochem Sci , vol.17 , pp. 37-39
    • Collins, S.1    Caron, M.G.2    Lefkowitz, R.J.3
  • 10
    • 0030756892 scopus 로고    scopus 로고
    • Endocytosis and recycling of G protein-coupled receptors
    • Koenig JA and Edwardson JM (1997) Endocytosis and recycling of G protein-coupled receptors. Trends Pharmacol Sci 18:276-286.
    • (1997) Trends Pharmacol Sci , vol.18 , pp. 276-286
    • Koenig, J.A.1    Edwardson, J.M.2
  • 11
    • 0028287951 scopus 로고
    • Kinetic analysis of the trafficking of muscarinic acetylcholine receptors between the plasma membrane and intracellular compartments
    • Koenig JA and Edwardson JM (1994) Kinetic analysis of the trafficking of muscarinic acetylcholine receptors between the plasma membrane and intracellular compartments. J Biol Chem 269:17174-17182.
    • (1994) J Biol Chem , vol.269 , pp. 17174-17182
    • Koenig, J.A.1    Edwardson, J.M.2
  • 12
    • 0031747997 scopus 로고    scopus 로고
    • The role of receptor kinases and arrestins in G protein-coupled receptor regulation
    • Krupnick JG and Benovic JL (1998) The role of receptor kinases and arrestins in G protein-coupled receptor regulation. Annu Rev Pharmacol Toxicol 38:289-319.
    • (1998) Annu Rev Pharmacol Toxicol , vol.38 , pp. 289-319
    • Krupnick, J.G.1    Benovic, J.L.2
  • 15
    • 0028520736 scopus 로고
    • Regulation of β-agonist and prostaglandin E2-mediated adenylyl cyclase activity in human airway epithelial cells
    • Penn RB, Kelsen SG and Benovic JL (1994) Regulation of β-agonist and prostaglandin E2-mediated adenylyl cyclase activity in human airway epithelial cells. Am J Respir Cell Mol Biol 11:496-505.
    • (1994) Am J Respir Cell Mol Biol , vol.11 , pp. 496-505
    • Penn, R.B.1    Kelsen, S.G.2    Benovic, J.L.3
  • 16
    • 0002731413 scopus 로고
    • Mechanisms of ligand-induced desenitization of beta-adrenergic receptors
    • Perkins JP ed Humana Press, Clifton, NJ
    • Perkins JP, Hausdorff WP and Lefkowitz RJ (1991) Mechanisms of ligand-induced desenitization of beta-adrenergic receptors, in The Beta-Adrenergic Receptor (Perkins JP ed) ch 3, pp 73-124, Humana Press, Clifton, NJ.
    • (1991) The Beta-Adrenergic Receptor , vol.3 , pp. 73-124
    • Perkins, J.P.1    Hausdorff, W.P.2    Lefkowitz, R.J.3
  • 18
    • 0021184389 scopus 로고
    • Relationship between intrinsic activities of agonists in normal and desensitized tissue and agonist-induced loss of beta adrenergic receptors
    • Pittman RN, Reynolds EE and Molinoff PB (1984) Relationship between intrinsic activities of agonists in normal and desensitized tissue and agonist-induced loss of beta adrenergic receptors. J Pharmacol Exp Ther 230:614-618.
    • (1984) J Pharmacol Exp Ther , vol.230 , pp. 614-618
    • Pittman, R.N.1    Reynolds, E.E.2    Molinoff, P.B.3
  • 19
    • 0027093257 scopus 로고
    • β-Adrenergic receptor levels and function after growth of 349 lymphoma cells in low concentrations of epinephrine
    • Proll MA, Clark RB, Goka TJ, Barber R and Butcher RW (1992) β-Adrenergic receptor levels and function after growth of 349 lymphoma cells in low concentrations of epinephrine. Mol Pharmacol 42:116-122.
    • (1992) Mol Pharmacol , vol.42 , pp. 116-122
    • Proll, M.A.1    Clark, R.B.2    Goka, T.J.3    Barber, R.4    Butcher, R.W.5
  • 20
    • 0016374975 scopus 로고
    • A highly sensitive adenylyl cyclase assay
    • Salomon Y, Londos C and Rodbell M (1974) A highly sensitive adenylyl cyclase assay. Anal Biochem 58:541-548.
    • (1974) Anal Biochem , vol.58 , pp. 541-548
    • Salomon, Y.1    Londos, C.2    Rodbell, M.3
  • 21
    • 0032571003 scopus 로고    scopus 로고
    • Desensitization of beta2-adrenergic receptors with mutations of the proposed G protein-coupled receptor kinase phosphorylation sites
    • Seibold A, January BG, Friedman J, Hipkin RW and Clark RB (1998) Desensitization of beta2-adrenergic receptors with mutations of the proposed G protein-coupled receptor kinase phosphorylation sites. J Biol Chem 273:7637-7642.
    • (1998) J Biol Chem , vol.273 , pp. 7637-7642
    • Seibold, A.1    January, B.G.2    Friedman, J.3    Hipkin, R.W.4    Clark, R.B.5
  • 22
    • 0027434162 scopus 로고
    • Down-regulation of beta-adrenergic receptors on mononuclear leukocytes induced by dobutamine treatment in patients with congestive heart failure
    • Teng JK, Kwan CM, Lin LJ, Tsai LM, Cheng JT, Chang WC and Chen JH (1993) Down-regulation of beta-adrenergic receptors on mononuclear leukocytes induced by dobutamine treatment in patients with congestive heart failure. Eur Heart J 14:1349-1353.
    • (1993) Eur Heart J , vol.14 , pp. 1349-1353
    • Teng, J.K.1    Kwan, C.M.2    Lin, L.J.3    Tsai, L.M.4    Cheng, J.T.5    Chang, W.C.6    Chen, J.H.7
  • 23
    • 0028330786 scopus 로고
    • Differential expression of the β-adrenergic receptor modifies agonist stimulation of adenylyl cyclase: A quantitative evaluation
    • Whaley BS, Yuan N, Birnbaumer L, Clark RB and Barber R (1994) Differential expression of the β-adrenergic receptor modifies agonist stimulation of adenylyl cyclase: A quantitative evaluation. Mol Pharmacol 45:481-489.
    • (1994) Mol Pharmacol , vol.45 , pp. 481-489
    • Whaley, B.S.1    Yuan, N.2    Birnbaumer, L.3    Clark, R.B.4    Barber, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.