Desensitization of β2-adrenergic receptors with mutations of the proposed G protein-coupled receptor kinase phosphorylation sites

Journal of Biological Chemistry

Volumn 273, Issue 13, 1998, Pages 7637-7642

  Seibold, Antia ^a   January, Bridgette G ^a   Friedman, Jacqueline ^a   Hipkin, R William ^a   Clark, Richard B ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; BETA 2 ADRENERGIC RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; GUANINE NUCLEOTIDE BINDING PROTEIN; RECOMBINANT PROTEIN; SERINE; THREONINE; TYROSINE KINASE RECEPTOR; ADENYLATE CYCLASE; BETA ADRENERGIC RECEPTOR KINASE; G PROTEIN COUPLED RECEPTOR KINASE 5; G-PROTEIN-COUPLED RECEPTOR KINASE 5; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE;

AMINO ACID SEQUENCE; ARTICLE; BETA ADRENERGIC STIMULATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; INTERNALIZATION; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION; BINDING SITE; CELL LINE; ENZYME ACTIVATION; GENETICS; METABOLISM; PHOSPHORYLATION; SITE DIRECTED MUTAGENESIS;

ADENYLATE CYCLASE; BETA-ADRENERGIC RECEPTOR KINASE; BINDING SITES; CELL LINE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME ACTIVATION; EPINEPHRINE; GTP-BINDING PROTEINS; HUMANS; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, ADRENERGIC, BETA-2;

EID: 0032571003     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.13.7637     Document Type: Article

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