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Volumn 14, Issue 10, 2000, Pages 1383-1388

Highly active antiretroviral therapy including protease inhibitors does not confer a unique CD4 cell benefit

Author keywords

CD4 cell count; HIV; Protease inhibitor; Viral load

Indexed keywords

ANTIRETROVIRUS AGENT; CD4 ANTIGEN; DIDANOSINE; NEVIRAPINE; NUCLEOSIDE; PROTEINASE INHIBITOR; RNA DIRECTED DNA POLYMERASE INHIBITOR; ZIDOVUDINE;

EID: 0033941115     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-200007070-00011     Document Type: Article
Times cited : (15)

References (26)
  • 1
    • 0030070991 scopus 로고    scopus 로고
    • Prognosis in HIV-1 infection predicted by the quantity of virus in plasma
    • 1. Mellors JW, Rinaldo CR Jr, Gupta P et al. Prognosis in HIV-1 infection predicted by the quantity of virus in plasma. Science 1996, 272:1167-1170.
    • (1996) Science , vol.272 , pp. 1167-1170
    • Mellors, J.W.1    Rinaldo C.R., Jr.2    Gupta, P.3
  • 2
    • 1842296349 scopus 로고    scopus 로고
    • Plasma viral load and CD4+ lymphocytes as prognostic markers of HIV-1 infection
    • 2. Mellors JW, Munoz A, Giorgi JV et al. Plasma viral load and CD4+ lymphocytes as prognostic markers of HIV-1 infection. Ann Intern Med 1997, 126:946-954.
    • (1997) Ann Intern Med , vol.126 , pp. 946-954
    • Mellors, J.W.1    Munoz, A.2    Giorgi, J.V.3
  • 3
    • 0032568194 scopus 로고    scopus 로고
    • The effects of lamivudine treatment on HIV-1 disease progression are highly correlated with plasma HIV-1 RNA and CD4 cell count
    • 3. Montaner JS, DeMasi R, Hill AM. The effects of lamivudine treatment on HIV-1 disease progression are highly correlated with plasma HIV-1 RNA and CD4 cell count. AIDS 1998, 12:F23-F28.
    • (1998) AIDS , vol.12
    • Montaner, J.S.1    DeMasi, R.2    Hill, A.M.3
  • 4
    • 0005150171 scopus 로고    scopus 로고
    • The relation of virologic and immunologic markers to clinical outcomes after nucleoside therapy in HIV-infected adults with 200 to 500 CD4 cells per cubic millimeter. AIDS Clinical Trials Croup Study 175 Virology Study Team
    • 4. Katzenstein DA, Hammer SM, Hughes MD et al. The relation of virologic and immunologic markers to clinical outcomes after nucleoside therapy in HIV-infected adults with 200 to 500 CD4 cells per cubic millimeter. AIDS Clinical Trials Croup Study 175 Virology Study Team. N Engl J Med 1996, 335:1091-1098.
    • (1996) N Engl J Med , vol.335 , pp. 1091-1098
    • Katzenstein, D.A.1    Hammer, S.M.2    Hughes, M.D.3
  • 5
    • 0007010412 scopus 로고    scopus 로고
    • Antiretroviral therapy for HIV infection in 1998: Updated recommendations of the International AIDS Society - USA Panel
    • 5. Carpenter CC, Fischl MA, Hammer SM et al. Antiretroviral therapy for HIV infection in 1998: updated recommendations of the International AIDS Society - USA Panel. J Am Med Assoc 1998, 280:78-86.
    • (1998) J Am Med Assoc , vol.280 , pp. 78-86
    • Carpenter, C.C.1    Fischl, M.A.2    Hammer, S.M.3
  • 6
    • 0442268112 scopus 로고    scopus 로고
    • A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team
    • 6. Hammer SM, Squires KE, Hughes MD et al. A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team. N Engl J Med 1997, 337:725-733.
    • (1997) N Engl J Med , vol.337 , pp. 725-733
    • Hammer, S.M.1    Squires, K.E.2    Hughes, M.D.3
  • 7
    • 0032492398 scopus 로고    scopus 로고
    • CD4-cell count in HIV-1-infected individuals remaining viraemic with highly active antiretroviral therapy (HAART). Swiss HIV Cohort Study
    • 7. Kaufmann D, Pantaleo G, Sudre P, Telenti A. CD4-cell count in HIV-1-infected individuals remaining viraemic with highly active antiretroviral therapy (HAART). Swiss HIV Cohort Study. Lancet 1998, 351:723-724.
    • (1998) Lancet , vol.351 , pp. 723-724
    • Kaufmann, D.1    Pantaleo, G.2    Sudre, P.3    Telenti, A.4
  • 8
    • 7144229335 scopus 로고    scopus 로고
    • Discrepant responses to triple combination antiretroviral therapy in advanced HIV disease
    • 8. Piketty C, Castiel P, Belec L et al. Discrepant responses to triple combination antiretroviral therapy in advanced HIV disease. AIDS 1998, 12:745-750.
    • (1998) AIDS , vol.12 , pp. 745-750
    • Piketty, C.1    Castiel, P.2    Belec, L.3
  • 9
    • 0033550965 scopus 로고    scopus 로고
    • Clinical progression and virological failure on highly active antiretroviral therapy in HIV-1 patients: A prospective cohort study. Swiss HIV Cohort Study
    • 9. Ledergerber B, Egger M, Opravil M et al. Clinical progression and virological failure on highly active antiretroviral therapy in HIV-1 patients: a prospective cohort study. Swiss HIV Cohort Study. Lancet 1999, 353:863-868.
    • (1999) Lancet , vol.353 , pp. 863-868
    • Ledergerber, B.1    Egger, M.2    Opravil, M.3
  • 10
    • 0032499143 scopus 로고    scopus 로고
    • Improvement in CD4+ cell counts despite persistently detectable HIV load
    • 10. Levitz SM. Improvement in CD4+ cell counts despite persistently detectable HIV load. N Engl J Med 1998, 338:1074.
    • (1998) N Engl J Med , vol.338 , pp. 1074
    • Levitz, S.M.1
  • 12
    • 0003305309 scopus 로고    scopus 로고
    • Viral fitness in patients with discordant CD4 and plasma HIV RNA evolution following protease inhibitor failure
    • Chicago, January-February [abstract 331]
    • 12. Faye A, Race E, Obry V et al. Viral fitness in patients with discordant CD4 and plasma HIV RNA evolution following protease inhibitor failure. Sixth Conference on Retroviruses and Opportunistic Infections. Chicago, January-February 1999 [abstract 331].
    • (1999) Sixth Conference on Retroviruses and Opportunistic Infections
    • Faye, A.1    Race, E.2    Obry, V.3
  • 14
    • 0032565098 scopus 로고    scopus 로고
    • A randomized, double-blind trial comparing combinations of nevirapine, didanosine, and zidovudine for HIV-infected patients: The INCAS Trial, Italy, The Netherlands, Canada and Australia Study
    • 14. Montaner JS, Reiss P, Cooper D et al. A randomized, double-blind trial comparing combinations of nevirapine, didanosine, and zidovudine for HIV-infected patients: the INCAS Trial, Italy, The Netherlands, Canada and Australia Study. J Am Med Assoc 1998, 279:930-937.
    • (1998) J Am Med Assoc , vol.279 , pp. 930-937
    • Montaner, J.S.1    Reiss, P.2    Cooper, D.3
  • 15
    • 0008532803 scopus 로고    scopus 로고
    • AVANTI 2: A randomized, double-blind, comparative trial to evaluate the efficacy, safety and tolerance of combination antiretroviral regimens for the treatment of HIV-1 infection: AZT/3TC vs. AZT/3TC/indinavir in antiretroviral naive patients
    • Toronto, September [abstract 1-87]
    • 15. Gerstoft J on behalf of the AVANTI Group. AVANTI 2: a randomized, double-blind, comparative trial to evaluate the efficacy, safety and tolerance of combination antiretroviral regimens for the treatment of HIV-1 infection: AZT/3TC vs. AZT/ 3TC/indinavir in antiretroviral naive patients. 37th International Congress on Antimicrobial Agents and Chemotherapy. Toronto, September 1997 [abstract 1-87].
    • (1997) 37th International Congress on Antimicrobial Agents and Chemotherapy
    • Gerstoft, J.1
  • 16
    • 0003207530 scopus 로고    scopus 로고
    • AVANTI 3: A randomized, double-blind, comparative trial to evaluate the efficacy, safety and tolerance of AZT/3TC vs AZT/3TC/nelfinavir in antiretroviral naïve patients
    • Chicago, February [abstract 8]
    • 16. Clumeck N for the AVANTI Study Group. AVANTI 3: a randomized, double-blind, comparative trial to evaluate the efficacy, safety and tolerance of AZT/3TC vs AZT/3TC/nelfinavir in antiretroviral naïve patients. Fifth Conference on Retroviruses and Opportunistic Infections, Chicago, February 1998 [abstract 8].
    • (1998) Fifth Conference on Retroviruses and Opportunistic Infections
    • Clumeck, N.1
  • 17
    • 16944363558 scopus 로고    scopus 로고
    • Correlation of virus load in plasma and lymph node tissue in human immunodeficiency virus infection. INCAS Study Croup, Italy, Netherlands, Canada, Australia and United States
    • 17. Harris M, Patenaude P, Cooperberg P et al. Correlation of virus load in plasma and lymph node tissue in human immunodeficiency virus infection. INCAS Study Croup, Italy, Netherlands, Canada, Australia and United States. J Infect Dis 1997, 176:1388-1392.
    • (1997) J Infect Dis , vol.176 , pp. 1388-1392
    • Harris, M.1    Patenaude, P.2    Cooperberg, P.3
  • 18
    • 0033389460 scopus 로고    scopus 로고
    • Suppression of plasma virus load below the detection limit of a human immunodeficiency virus kit is associated with longer virologic response than suppression below the limit of quantitation
    • 18. Raboud JM, Rae S, Hogg RS et dl. Suppression of plasma virus load below the detection limit of a human immunodeficiency virus kit is associated with longer virologic response than suppression below the limit of quantitation. J Infect Dis 1999, 180:1347-1350.
    • (1999) J Infect Dis , vol.180 , pp. 1347-1350
    • Raboud, J.M.1    Rae, S.2    Hogg, R.S.3
  • 19
    • 0028069547 scopus 로고
    • Rapid and simple PCR assay for quantitation of human immunodeficiency virus type-1 RNA in plasma: Application to acute retroviral infection
    • 19. Mulder J, Christopherson C, Sninsky J, Kwok S. Rapid and simple PCR assay for quantitation of human immunodeficiency virus type-1 RNA in plasma: application to acute retroviral infection. J Clin Microbiol 1994, 32:292-300.
    • (1994) J Clin Microbiol , vol.32 , pp. 292-300
    • Mulder, J.1    Christopherson, C.2    Sninsky, J.3    Kwok, S.4
  • 20
    • 0030949848 scopus 로고    scopus 로고
    • A rapid and simple method for extracting human immunodeficiency virus type 1 RNA from plasma: Enhanced sensitivity
    • 20. Mulder J, Resnick R, Saget B et al. A rapid and simple method for extracting human immunodeficiency virus type 1 RNA from plasma: enhanced sensitivity. J Clin Microbiol 1997, 35: 1278-1280.
    • (1997) J Clin Microbiol , vol.35 , pp. 1278-1280
    • Mulder, J.1    Resnick, R.2    Saget, B.3
  • 21
    • 0031656727 scopus 로고    scopus 로고
    • Ultrasensitive reverse transcription-PCR assay for quantitation of human immunodeficiency virus type 1 RNA in plasma
    • 21. Sun R, Ku J, Jayakar H et al. Ultrasensitive reverse transcription-PCR assay for quantitation of human immunodeficiency virus type 1 RNA in plasma. Clin Microbiol 1998, 36:2964-2969.
    • (1998) Clin Microbiol , vol.36 , pp. 2964-2969
    • Sun, R.1    Ku, J.2    Jayakar, H.3
  • 22
    • 0028344275 scopus 로고
    • MRC/ANRS randomised double-blind controlled trial of immediate and deferred zidovudine in symptom-free HIV infection. Concorde Coordinating Committee
    • 22. Concorde. MRC/ANRS randomised double-blind controlled trial of immediate and deferred zidovudine in symptom-free HIV infection. Concorde Coordinating Committee. Lancet 1994, 343:871-881.
    • (1994) Lancet , vol.343 , pp. 871-881
  • 23
    • 0030484637 scopus 로고    scopus 로고
    • The treatment of antiretroviral-naive subjects with the 3TC/zidovudine combination: A review of North American (NUCA 3001) and European (NUCB 3001) trials
    • 23. Eron JJ Jr. The treatment of antiretroviral-naive subjects with the 3TC/zidovudine combination: a review of North American (NUCA 3001) and European (NUCB 3001) trials. AIDS 1996, 10(Suppl 5):S11-S19.
    • (1996) AIDS , vol.10 , Issue.SUPPL. 5
    • Eron J.J., Jr.1
  • 24
    • 0033010260 scopus 로고    scopus 로고
    • Immune restoration does not invariably occur following long-term HIV-1 suppression during antiretroviral therapy. INCAS Study Group
    • 24. Pakker NG, Kroon ED, Roos MT et al. Immune restoration does not invariably occur following long-term HIV-1 suppression during antiretroviral therapy. INCAS Study Group. AIDS 1999, 13:203-212.
    • (1999) AIDS , vol.13 , pp. 203-212
    • Pakker, N.G.1    Kroon, E.D.2    Roos, M.T.3
  • 25
    • 0003348142 scopus 로고    scopus 로고
    • Discordant CD4/RNA responses to HAART are strongly associated with high baseline CD4 cell count and low HIV RNA: Analysis of 406 naive patients
    • San Diego, June [poster 152]
    • 25. Hill A, Montaner JS, Lederman M for the CNA3005 Study Group. Discordant CD4/RNA responses to HAART are strongly associated with high baseline CD4 cell count and low HIV RNA: analysis of 406 naive patients. Third International Workshop on Drug Resistance and Treatment Strategies. San Diego, June 1999 [poster 152].
    • (1999) Third International Workshop on Drug Resistance and Treatment Strategies
    • Hill, A.1    Montaner, J.S.2    Lederman, M.3
  • 26
    • 0033004630 scopus 로고    scopus 로고
    • Rate of HIV-1 RNA rebound upon stopping antiretroviral therapy
    • 26. Harrigan PR, Whaley M, Montaner JS. Rate of HIV-1 RNA rebound upon stopping antiretroviral therapy. AIDS 1999, 28:F59-F62.
    • (1999) AIDS , vol.28
    • Harrigan, P.R.1    Whaley, M.2    Montaner, J.S.3


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