Clinicopathologic features and FHIT gene expression in sporadic colorectal adenocarcinomas

Scandinavian Journal of Gastroenterology

Volumn 35, Issue 6, 2000, Pages 637-641

  Luceri, Cristina ^a   Guglielmi, F ^a   De Filippo, C ^a   Caderni, G ^a   Mini, E ^a   Biggeri, A ^a   Napoli, C ^a   Tonelli, F ^a   Cianchi, F ^a   Dolara, P ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Aberrant transcripts; Colorectal carcinomas; FHIT gene; Tumour suppressor gene

Indexed keywords

FRAGILE HISTIDINE TRIAD PROTEIN;

ADENOCARCINOMA; ADULT; AMINO ACID SEQUENCE; ARTICLE; CLINICAL FEATURE; COLORECTAL CARCINOMA; FEMALE; FOLLOW UP; GENE DELETION; GENE EXPRESSION; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

EID: 0033937149     PISSN: 00365521     EISSN: None     Source Type: Journal    
DOI: 10.1080/003655200750023615     Document Type: Article

References (23)

1. 1. Kok H, Osinga J, Carrit B, Davis MB, van der Veen AY, Landsvater RM, et al. Deletion of DNA sequences at the chromosomal region 3p21 in all major types of lung adenocarcinoma. Nature 1987;330:578-81.
2. 2. Zbar B, Brauch H, Talmadge C, Linehan M. Loss of alleles of loci on the short arm of chromosome 3 in renal cell carcinoma. Nature 1987;327:721-4.
3. 3. Shimizu M, Yokota J, Mori N, Shuin T, Shinoda M, Terada M. Introduction of normal chromosome 3p modulates the tumorigenicity of a human renal cell carcinoma cell line YCR. Oncogene 1990;5:185-94.
4. 4. Ohta M, Inoue H, Cotticelli MG, Kastury K, Baffa R, Palazzo J, et al. The human FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated translocation breakpoint, is abnormal in digestive tract adenocarcinomas. Cell 1996;84:587-97.
5. 5. Wilke CM, Hall BK, Hoge A, Paradee W, Smith DI, Glover TW. FRA3B extends over a broad region and contains a spontaneous HPV16 integration site: direct evidence for the coincidence of viral integration sites and fragile sites. Hum Mol Genet 1996;5:187-95.
6. 6. Rassool FV, Le Beau MM, Shen ML, Neilly ME, Espinoza RR, Ong ST, et al. Direct cloning of DNA sequences from the common fragile site region at chromosome band 3p14.2. Genomics 1996;35:109-17.
7. 7. Kastury K, Baffa R, Druck T, Otha M, Cotticelli MG, Inoue H, et al. Potential gastrointestinal tumor suppressor locus at the 3p14.2 FRA3B site identified by homozygous deletions in tumor cell lines. Adenocarcinoma Res 1996;56:978-83.
8. 8. Sutherland GR. Chromosomal fragile sites. Genet Anal Tech Appl 1991;8:161-6.
9. 9. Mao L, Fan YH, Lotan R, Hong WK. Frequent abnormalities of FHIT, a candidate tumor suppressor gene, in head and neck adenocarcinoma cell lines. Adenocarcinoma Res 1996;51:5128-31.
10. 10. Sozzi G, Veronese ML, Negrini M, Baffa R, Cotticelli MG, Inoue H, et al. The FHIT gene at 3p14.2 is abnormal in lung adenocarcinoma. Cell 1996;85:17-26.
11. 11. Bartsch SB, Barth D, Prasnikar N, Munch K, Blum A, Arnold R, et al. Frequent abnormalities of the putative tumor suppressor gene FHIT at 3p14.2 in pancreatic carcinoma cell lines. Adenocarcinoma Res 1998;58:1583-7.
12. 12. Marchetti A, Pellegrini S, Sozzi G, Bertacca G, Gaeta P, Buttitta F, et al. Genetic analysis of lung tumors of non-smoking subjects: p53 gene mutations are constantly associated with loss of heterozygosity at the FHIT locus. Br J Adenocarcinoma 1998;78:73-8.
13. 13. Nelson HH, Wiencke JK, Gunn L, Wain JC, Christiani DC, Kelsey KT. Chromosome 3p14 alterations in lung adenocarcinoma: evidence that FHIT exon deletion is a target of tobacco carcinogens and asbestos. Adenocarcinoma Res 1998;58: 1804-7.
14. 14. Chen YJ, Chen PH, Lee MD, Chang JG. Aberrant FHIT transcripts in cancerous and corresponding non-cancerous lesions of the digestive tract. Int J Cancer 1997;72:955-8.
15. 15. Negrini K, Monaco C, Vorechovsky I, Ohta M, Druck T, Baffa R, et al. The FHIT gene at 3p14.2 is abnormal in breast carcinomas. Adenocarcinoma Res 1996;56:3173-9.
16. 16. Ahamadian M, Wistuba II, Fong KM, Behrens C, Kodagoda DR, Saboorian MH, et al. Analysis of the FHIT gene and FRA3B region in sporadic breast adenocarcinoma preneoplastic lesions, and familial breast adenocarcinoma probants. Adenocarcinoma Res 1997;57:3664-8.
17. 17. Michael D, Beer DG, Wilke CW, Miller DE, Glover TW. Frequent deletions of FHIT and FRA3B in Barrett's metaplasia and esophageal adenocarcinomas. Oncogene 1997;15:1653-9.
18. 18. Barnes LD, Garrison PN, Siprashvili Z, Guranowski A, Robinson AK, Ingram SW, et al. FHIT, a putative tumor suppressor in humans, is a dinucleoside 5′, 5″-P1, P3-triphosphate hydrolase. Biochemistry 1996;35:11529-35.
19. 19. Weinmann-Dorsch O, Hedl A, Grummt I, Albert W, Ferdinand FJ, Früs RR, et al. Drastic rise of intracellular adenosine (5′) tetraphospho (5′) adenosine correlates with onset of DNA synthesis in eukaryotic cells. Eur J Biochem 1984;138:179-85.
20. 20. Vartanian A, Prudovsky I, Suzuki H, Dal Pra I, Kisselev L. Opposite effects of cells differentiation and apoptosis on Ap3A/ Ap4A ratio in human cell cultures. FEBS Lett 1997;415:160-2.
21. 21. Baker JC, Jacobson MK. Alteration of adenyl dinucleotide metabolism by environmental stress. Proc Natl Acad Sci 1986; 83:2355-62.
22. 22. Siprashvili Z, Sozzi G, Barnes LD, McCue P, Robinson AK, Eryomin V, et al. Replacement of FHIT in adenocarcinoma cells suppresses tumorigenicity. Proc Natl Acad Sci USA 1997;94: 13771-6.
23. 23. Burke L, Khan MA, Freedman AN, Gemma A, Rusin M, Guinec DG, et al. Allelic deletion analysis of the FHIT gene predicts poor survival in non-small cell lung adenocarcinoma. Adenocarcinoma Res 1998;58:2533-6.