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The FHIT and PTPRG genes are deleted in benign proliferative breast disease associated with familial breast cancer and cytogenetic rearrangements of chromosome band 3p14
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Allele-specific chromosome 3p deletions occur at an early stage in the pathogenesis of lung carcinoma
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FHIT and FRA3B 3p14.2 allele loss are common in lung cancer and preneoplastic bronchial lesions and are associated with cancer-related FHIT cDNA splicing aberrations
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Fong, K. M., Biesterveld, E. J., Virmani, A., Wistuba, I., Sekido, Y., Bader, S. A., Ahmadian., M., Tiong Ong, S., Rassool, F. V., Zimmerman, P. V., Giaccone, G., Gazdar, A. F., and Minna, J. D. FHIT and FRA3B 3p14.2 allele loss are common in lung cancer and preneoplastic bronchial lesions and are associated with cancer-related FHIT cDNA splicing aberrations. Cancer Res., 57: 2256-2267, 1997.
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FRA3B extends over a broad region and contains a spontaneous HPV16 integration site: Direct evidence for the coincidence of viral integration sites and fragile sites
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Positions of chromosome 3p14.2 fragile sites (FRA3B) within the FHIT gene
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