Aberrant FHIT transcripts in cancerous and corresponding non-cancerous lesions of the digestive tract

International Journal of Cancer

Volumn 72, Issue 6, 1997, Pages 955-958

  Chen, Yi Jen ^a   Chen, Pao Huei ^b   Lee, Meng Dar ^b   Chang, Jan Gowth ^b  

^a TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b JEN AI HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CARCINOGENESIS; CLINICAL ARTICLE; DIGESTIVE SYSTEM CANCER; EXON; FEMALE; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; SEQUENCE ANALYSIS; TUMOR SUPPRESSOR GENE;

ACID ANHYDRIDE HYDROLASES; BASE SEQUENCE; COLORECTAL NEOPLASMS; ESOPHAGEAL NEOPLASMS; ESOPHAGUS; EXONS; FEMALE; GASTRIC MUCOSA; HUMANS; INTESTINAL MUCOSA; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUCOUS MEMBRANE; NEOPLASM PROTEINS; POLYMERASE CHAIN REACTION; PROTEIN BIOSYNTHESIS; PROTEINS; REFERENCE VALUES; SEQUENCE DELETION; STOMACH NEOPLASMS; TRANSCRIPTION, GENETIC;

EID: 0030754330     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19970917)72:6<955::AID-IJC6>3.0.CO;2-O     Document Type: Article

References (18)

1. 3 triphosphate hydrolase. Biochemistry, 35, 11529-11535 (1996).
2. BOLDOG, F. and 13 OTHERS, Chromosome 3p14 homozygous deletions and sequence analysis of FRA3B. Hum. mol. Genet., 6, 193-203 (1997).
3. DRUCK, T. and 15 OTHERS, Structure and expression of the human FHIT gene in normal and tumor cells. Cancer Res., 57, 504-512 (1997).
4. 4-tetraphosphate [ap(4)a] asymmetrical hydrolase: sequence similarity with the histidinetriad(HIT) protein family. Biochem. J., 312, 925-932 (1995).
5. KASTURY, K., BAFFA, R., DRUCK, T., OHTA, M., COTTICELLI, M.G., INOUE, H., NEGRINI, M., RUGGE, M., HUANG, D., CROCE, C.M., PALAZZO, J. and HUEBNER, K., Potential gastro-intestinal tumor-suppressor locus at the 3p14.2 FRA3B site identified by homozygous deletions in tumor cell lines. Cancer Res., 56, 978-983 (1996).
6. NAYLOR, S.L., JOHNSON, B.E., MINNA, J.D. and SAKAGUCHI, A.Y., Loss of heterozygosity of chromosome 3p markers in small-cell lung cancer. Nature (Lond.), 329, 451-454 (1987).
7. NEGRINI, M., MONACO, C., VORECHOVSKY, I., OHTA, M., DRUCK, T., BAFFA, R., HUEBNER, K. and CROCE, C.M., The FHIT gene at 3p14.2 is abnormal in breast carcinomas. Cancer Res., 56, 3173-3179 (1996).
8. NOBORI, T., MIURA, K., WU, D.J., LOIS, A., TAKABAYASHI, K. and CARSON, D.A., Deletions of the cyclin-dependent kinase-4-inhibitor gene in multiple human cancers. Nature (Lond.), 368, 753-756 (1994).
9. OHTA, M., INOUE, H., COTTICELLI, M.G., KASTURY, K., BAFFA, R., PALAZZO, J., SIPRASHVTLI, Z., MORI, M., MCCUE, P., DRUCK, T., CROCE, M.C. and HUEBNER, K., The human FHIT gene, spanning the chromosome 3p14.2 fragile site and renal-carcinoma-associated translocation breakpoint, is abnormal in digestive-tract cancers. Cell. 84, 587-597 (1996).
10. PARADEE, W., MULLINS, C., HE, Z., GLOVER, T., WILKE, C., OPALKA, B., SCHUTTE, J. and SMITH, D., Precise localization of aphidicolin-induced breakpoints on the short arm of human chromosome 3. Genomics, 27, 358-361 (1995).
11. POPESCU, N.C., ZIMONJIC, D.B., LEVENTON, K.S., BRYANT, J.L., LUNARDI, I.Y. and GALLO, R.C., Deletion and translocation involving chromosome 3(p14) in two tumorigenic Kaposi's-sarcoma cell lines. J. nat. Cancer Inst., 88, 450-455 (1996).
12. SOZZI, G. and 13 OTHERS, The FHIT gene at 3p14.2 is abnormal in lung cancer. Cell. 85, 17-26 (1996a).
13. SOZZI, G., ALDER, H., TORKIELLI, S., CORLETTO, V., BAFFA, R., VERONESE, M.L., NEORINI, M., PILOTTI, S., PIEROTTI, M.A., HUEBNER, K. and CROCE, C.M., Aberrant FHIT transcripts in merkel-cell carcinoma. Cancer Res., 56, 2472-2474 (1996b).
14. STEPHEN, F.A., GISH, W., MILLER, W., MYERS, E.W. and LIPMAN, D.J., Basic local alignment search tool. J. mol. Biol., 215, 403-410 (1990).
15. SUTHERLAND, G.R., Chromosomal fragile sites. Genet. Anal. Tech. Appl., 8, 161-166 (1991).
16. THIAGALINGAM, S., LISITSYN, N.A., HAMAGUCHI, M., WIGLER, M.H., WILLSON, J.K.V., MARKOWITZ, S.D., LEACH, F.S., KINZLER, K.W. and VOGELSTEIN, B., Evaluation of the FHIT gene in colorectal cancers. Cancer Res., 56, 2936-2939 (1996).
17. ZBAR, B., BRAUCH, H., TALMADOE, C. and LINEHAN, M., Loss of alleles of loci on the short arm of chromosome 3 in renal-cell carcinoma. Nature (Lond.), 327, 721-724 (1987).
18. ZEIGER, M.A., GNARRA, J.R., ZBAR, B., LINEHAN, W.M. and PASS, H.I., Loss of heterozygosity on the short arm of chromosome 3 in mesothelioma cell lines and solid tumors. Genes Chromosomes Cancer. 11, 15-20 (1994).