Sphingomyelin exhibits greatly enhanced protection compared with egg yolk phosphatidylcholine against detergent bile salts

Journal of Lipid Research

Volumn 41, Issue 6, 2000, Pages 916-924

  Moschetta, Antonio ^a   VanBerge Henegouwen, Gerard P ^a   Portincasa, Piero ^c   Palasciano, Giuseppe ^c   Groen, Albert K ^b   Van Erpecum, Karel J ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c NONE

Author keywords

Bile salts; CaCo 2 cells; Erythrocytes; Intermixed micellar vesicular bile salt concentration; Micelles; Phosphatidylcholine; Phospholipids; Sphingomyelin; Vesicl es

Indexed keywords

BILE SALT; LACTATE DEHYDROGENASE; PHOSPHATIDYLCHOLINE; SPHINGOMYELIN;

ARTICLE; CELL PROTECTION; COMPARATIVE STUDY; CYTOTOXICITY; EGG YOLK; ENZYME RELEASE; HEMOLYSIS; HUMAN; HUMAN CELL; MICELLE; PRIORITY JOURNAL;

BILE ACIDS AND SALTS; CACO-2 CELLS; DETERGENTS; EGG YOLK; HEMOLYSIS; HUMANS; PHOSPHATIDYLCHOLINES; SPHINGOMYELINS;

EID: 0033935502     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Barnwell, S. G., P. J. Lowe, and R. Coleman. 1983. Effect of taurochenodeoxycholate or tauroursodeoxycholate upon biliary output of phospholipids and plasma-membrane enzymes, and the extent of cell damage, in isolated perfused rat livers. Biochem. J. 216: 107-111.
2. Heuman, D. M., W. M. Pandak, P. B. Hylemon, and Z. R. Vlahcevic. 1991. Conjugates of ursodeoxycholate protect against cytotoxicity of more hydrophobic bile salts: in vitro studies in rat hepatocytes and human erythrocytes. Hepatology. 14: 920-926.
3. Coleman, R., S. Iqbal, P. P. Godfrey, and D. Billington. 1979. Membranes and bile formation. Composition of several mammalian biles and their membrane-damaging properties. Biochem. J. 178: 201-208.
4. Lowe, P. J., and R. Coleman. 1981. Membrane fluidity and bile salt damage. Biochim. Biophys. Acta. 640: 55-65.
5. Davenport, H. W. 1968. Destruction of the gastric mucosal barrier by detergent and urea. Gastroenterology. 54: 175-181.
6. Chadwick, V. S., T. S. Gaginella, G. L. Carlson, J. C. Debognie, S. F. Phillips, and A. Hoffmann. 1979. Effect of molecular structure on bile acid-induced alterations in absorptive function, permeability, and morphology in the perfused rabbit colon. J. Lab. Clin. Med. 94: 661-674.
7. Ostrow, J. D. 1969. Absorption by the gallbladder of bile salts, sulfobromophthalein and iodipamide. J. Lab. Clin. Med. 74: 482-494.
8. Ostrow, J. D. 1967. Absorption of bile pigments by the gallbladder. J. Clin. Invest. 46: 2035-2052.
9. Coleman, R. 1987. Bile salts and biliary lipids. Biochem. Soc. Trans. 15: 68S-80S.
10. Coleman, R., P. J. Lowe, and D. Billington. 1980. Membrane lipid composition and susceptibility to bile salt damage. Biochim. Biophys. Acta. 599: 294-300.
11. Donovan, J. M., N. Timofeyeva, and M. C. Carey. 1991. Influence of total lipid concentration, bile salt:lecithin ratio, and cholesterol content on inter-mixed micellar/vesicular (non-lecithin-associated) bile salt concentrations in model bile. J. Lipid Res. 32: 1501-1512.
12. Donovan, J. M., A. A. Jackson, and M. C. Carey. 1993. Molecular species composition of inter-mixed micellar/vesicular bile salt concentrations in model bile: dependence upon hydrophilic-hydrophobic balance. J. Lipid Res. 34: 1131-1140.
13. Narain, P. K., E. J. DeMaria, and D. M. Heuman. 1998. Lecithin protects against plasma membrane disruption by bile salts. J. Surg. Res. 78: 131-136.
14. Amigo, L., H. Mendoza, S. Zanlungo, J. F. Miquel, A. Rigotti, S. Gonzalez, and F. Nervi. 1999. Enrichment of canalicular membrane with cholesterol and sphingomyelin prevents bile salt-induced hepatic damage. J. Lipid Res. 40: 533-542.
15. Schachter, D. 1988. The hepatocyte plasma membrane: organization and differentiation. In The Liver: Biology and Pathobiology. I. M. Arias, W. B. Jakoby, H. Popper, D. Schachter, and D. A. Shafritz, editors. Raven Press, Ltd., New York, NY. 131-140.
16. Kremmer, T., M. H. Wisher, and W. H. Evans. 1976. The lipid composition of plasma membrane subfractions originating from the three major functional domains of the rat hepatocyte cell surface. Biochim. Biophys. Acta. 455: 655-664.
17. Velardi, A. L. M., A. K. Groen, R. P. Oude Elferink, R. van der Meer, G. Palasciano, and G. N. Tytgat. 1991. Cell type-dependent effect of phospholipid and cholesterol on bile salt cytotoxicity. Gastroenterology. 101: 457-404.
18. Smit, J. J., A. H. Schinkel, R. P. J. Oude Elferink, A. K. Groen, E. Wagenaar, L. van Deemter, C. A. Mol, R. Ottenhoff, N. M. van der Lugt, and M. A. van Roon. 1993. Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease. Cell. 75: 451-462.
19. Higgins, J. A., and W. H. Evans. 1978. Transverse organization of phospholipids across the bilayer of plasma membrane subfractions of rat hepatocytes. Biochem. J. 174: 563-567.
20. Alvaro, D., A. Cantafora, A. F. Attili, G. S. Ginanni, C. De Luca, G. Minervini, A. Di Biase, and M. Angelico. 1986. Relationships between bile salts hydrophilicity and phospholipid composition in bile of various animal species. Comp. Biochem. Physiol. B. 83: 551-554.
21. Barnwell, S. G., B. Tuchweber, and I. M. Yousef. 1987. Biliary lipid secretion in the rat during infusion of increasing doses of unconjugated bile acids. Biochim. Biophys. Acta. 922: 221-233.
22. Duan, R. D., E. Hertervig, L. Nyberg, T. Hange, B. Sternby, J. Lillienau, A. Farooqi, and A. Nilsson. 1996. Distribution of alkaline sphingomyelinase activity in human beings and animals. Time and species differences. Dig. Dis. Sci. 41: 1801-1806.
23. van Erpecum, K. J., and M. C. Carey. 1997. Influence of bile salts on molecular interactions between sphingomyelin and cholesterol: relevance to bile formation and stability. Biochim. Biophys. Acta. 1345: 269-282.
24. Hay, D. W., M. J. Cahalane, N. Timofeyeva, and M. G. Carey. 1993. Molecular species of lecithins in human gallbladder bile. J. Lipid Res. 34: 759-768.
25. Nibbering, C. P., and M. C. Carey. 1999. Sphingomyelins of rat liver: biliary enrichment with molecular species containing 16:0 fatty acids as compared to canalicular-enriched plasma membranes. J. Membr. Biol. 167: 165-171.
26. Koynova, R., and M. Caffrey. 1995. Phases and phase transitions of the sphingolipids. Biochim. Biophys. Acta. 1255: 213-236.
27. Hakomori, S. 1983. Chemistry of Glycosphingolipids. In Handbook of Lipid Research. D. J. Hanahan, editor. Plenum Press, New York, NY. 37-39.
28. Turley, S. D., and J. M. Dietschy. 1978. Reevaluation of the 3α-hydroxysteroid dehydrogenase assay for total bile acids in bile. J. Lipid Res. 19: 924-928.
29. Rouser, G., S. Fleischer, and A. Yamamoto. 1970. Two dimensional thin layer chromatographic separation of polar lipids and determination of phospholipids by phosphorus analysis of spots. Lipids. 5: 494-496.
30. Fromm, H., P. Hamin, H. Klein, and I. Kupke. 1980. Use of a simple enzymatic assay for cholesterol analysis in human bile. J. Lipid Res. 21: 259-261.
31. Carey, M. C. 1978. Critical tables for calculating the cholesterol saturation of native bile. J. Lipid Res. 19: 945-965.
32. Carey, M. C., and D. M. Small. 1978. The physical chemistry of cholesterol solubility in bile. Relationship to gallstone formation and dissolution in man. J. Clin. Invest. 61: 998-1026.
33. Wang, D. Q. H., and M. C. Carey. 1996. Complete mapping of crystallization pathways during cholesterol precipitation from model bile: influence of physical-chemical variables of pathophysiologic relevance and identification of a stable liquid crystalline state in cold, dilute and hydrophilic bile salt-containing systems. J. Lipid Res. 37: 606-630.
34. Reed, C. F., S. N. Swisher, G. V. Marinetti, and E. G. Eden. 1960. Studies of the lipids of the erythrocyte. I. Quantitative analysis of the lipids of normal human red blood cells. J. Lab. Clin. Med. 56: 281-289.
35. Mohrmann, I., M. Mohrmann, J. Biber, and H. Urer. 1986. Sodium-dependent transport of Pi by an established intestinal epithelial cell line (CaCo-2). Am. J. Physiol. 250: G323-G330.
36. Mitchell, D. B., K. S. Santone, and D. Acosta. 1980. Evaluation of cytotoxicity in cultured cells by enzyme leakage. J. Tissue Cult. Methods. 6: 113-116.
37. Donovan, J. M., and A. A. Jackson. 1993. Rapid determination by centrifugal ultrafiltration of inter-mixed micellar/vesicular (non-lecithin-associated) bile salt concentrations in model bile: influence of Donnan equilibrium effects. J. Lipid Res. 34: 1121-1129.
38. Eckhardt, E. R. M., B. J. M. van de Heijning, K. J. van Erpecum, W. Renooij, and G. P. vanBerge-Henegouwen. 1998. Quantitation of cholesterol-carrying particles in human gallbladder bile. J. Lipid Res. 39: 594-603.
39. Hori, T., K. Matsumoto, Y. Sakaitani, M. Sato, and M. Morotomi. 1998. Effect of dietary deoxycholic acid and cholesterol on fecal steroid concentration and its impact on the colonic crypt cell proliferation in azoxymethane-treated rats. Cancer Lett. 124: 79-84.
40. Estep, T. N., W. I. Calhoun, Y. Barenholz, R. L. Biltonen, G. G. Shipley, and T. E. Thompson. 1980. Evidence for metastability in stearoylsphingomyelin bilayers. Biochemistry. 19: 20-24.
41. Kuypers, F. A., B. Roelofsen, W. Berendsen, J. A. Op den Kamp, and L. L. van Deenen. 1984. Shape changes in human erythrocytes induced by replacement of the native phosphatidylcholine with species containing various fatty acids. J. Cell Biol. 99: 2260-2267.
42. Schubert, R., and K-H. Schmidt. 1988. Structural changes in vesicle membranes and mixed micelles of various lipid compositions after binding of different bile salts. Biochemistry. 27: 8787-8794.
43. Mazer, N. A., G. B. Benedek, and M. C. Carey. 1980. Quasielastic light-scattering studies of aqueous biliary lipid systems. Mixed micelle formation in bile salt-lecithin solutions. Biochemistry. 19: 601-615.
44. Yousef, I. M., and M. M. Fisher. 1976. In vitro effect of free bile acids on the bile canalicular membrane phospholipids in the rat. Can. J. Biochem. 54: 1040-1046.
45. Gerloff, T., P. J. Meier, and B. Stieger. 1998. Taurocholate induces preferential release of phosphatidylcholine from rat liver canalicular vesicles. Liver. 18: 306-312.
46. Billington, D., R. Coleman, and Y. A. Lusak. 1977. Topographical dissection of sheep erythrocyte membrane phospholipids by taurocholate and glycocholate. Biochim. Biophys. Acta. 466: 526-530.
47. Thimister, P. W. L., W. P. M. Hopman, C. E. J. Sloots, G. Rosenbusch, A. Tangerman, H. L. Willems, C. B. H. W. Lamers, and J. B. M. J. Jansen. 1994. Effect of bile salt binding or protease inactivation on plasma cholecystokinin and gallbladder responses to bombesin. Gastroenterology. 107: 1627-1635.
48. Dillehay, D. L., S. K. Webb, E. M. Schmelz, and A. H. J. Merrill. 1994. Dietary sphingomyelin inhibits 1,2-dimethylhydrazine-induced colon cancer in CF1 mice. J. Nutr. 124: 615-620.
49. Parodi, P. W. 1997. Cows' milk fat components as potential anticarcinogenic agents. J. Nutr. 127: 1055-1060.