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Volumn 79, Issue 6, 2000, Pages 377-382

The relation of protein binding to function: What is the significance of munc18 and synaptotagmin binding to syntaxin 1, and where are the corresponding binding sites?

Author keywords

GST pulldowns; munc18; Synaptotagmin; Syntaxin 1

Indexed keywords

MUTANT PROTEIN; SNARE PROTEIN; SYNAPTOBREVIN; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; SYNAPTOTAGMIN; SYNTAXIN;

EID: 0033934941     PISSN: 01719335     EISSN: None     Source Type: Journal    
DOI: 10.1078/0171-9335-00063     Document Type: Article
Times cited : (28)

References (36)
  • 1
    • 0022071726 scopus 로고
    • A marker of early amacrine cell development in rat retina
    • Barnstable, C. J., Hofstein, R., Akagawa, K. (1985): A marker of early amacrine cell development in rat retina. Brain Res. 352, 286-290.
    • (1985) Brain Res. , vol.352 , pp. 286-290
    • Barnstable, C.J.1    Hofstein, R.2    Akagawa, K.3
  • 2
    • 0026778460 scopus 로고
    • Syntaxin: A synaptic protein implicated in docking of synaptic vesicles at presynaptic active zones
    • Bennett, M. K., Calakos, N., Scheller, R. H. (1992): Syntaxin: a synaptic protein implicated in docking of synaptic vesicles at presynaptic active zones. Science 257, 255-259.
    • (1992) Science , vol.257 , pp. 255-259
    • Bennett, M.K.1    Calakos, N.2    Scheller, R.H.3
  • 3
    • 0027432376 scopus 로고
    • Botulinum neurotoxin c1 blocks neurotransmitter release by means of cleaving HPC-1/syntaxin
    • Blasi, J., Chapman, E. R., Yamasaki, S., Binz, T., Niemann, H., Jahn, R. (1993): Botulinum neurotoxin C1 blocks neurotransmitter release by means of cleaving HPC-1/syntaxin. EMBO J. 12, 4821-4828.
    • (1993) EMBO J. , vol.12 , pp. 4821-4828
    • Blasi, J.1    Chapman, E.R.2    Yamasaki, S.3    Binz, T.4    Niemann, H.5    Jahn, R.6
  • 4
  • 5
    • 0033606766 scopus 로고    scopus 로고
    • Sec1p binds to SNARE complexes and concentrates at sites of secretion
    • Carr, C. M., Grote, E., Munson, M., Hughson, F. M., Novick, P. J. (1999): Sec1p binds to SNARE complexes and concentrates at sites of secretion. J. Cell Biol. 146, 333-344.
    • (1999) J. Cell Biol. , vol.146 , pp. 333-344
    • Carr, C.M.1    Grote, E.2    Munson, M.3    Hughson, F.M.4    Novick, P.J.5
  • 6
    • 0028970788 scopus 로고
    • 2+ regulates the interaction between synaptotagmin and syntaxin 1
    • 2+ regulates the interaction between synaptotagmin and syntaxin 1. J. Biol. Chem. 270, 23667-23671.
    • (1995) J. Biol. Chem. , vol.270 , pp. 23667-23671
    • Chapman, E.R.1    Hanson, P.I.2    An, S.3    Jahn, R.4
  • 7
    • 0030054915 scopus 로고    scopus 로고
    • Mammalian Sly1 regulates syntaxin 5 function in endoplasmic reticulum to Golgi transport
    • Dascher, C., Balch, W. E. (1996): Mammalian Sly1 regulates syntaxin 5 function in endoplasmic reticulum to Golgi transport. J. Biol. Chem. 271, 15866-15869.
    • (1996) J. Biol. Chem. , vol.271 , pp. 15866-15869
    • Dascher, C.1    Balch, W.E.2
  • 8
    • 0032523028 scopus 로고    scopus 로고
    • A neuronal Sec1 homolog regulates neurotransmitter release at the squid giant synapse
    • Dresbach, T., Burns, M. E., O'Connor, V., DeBello, W. M., Betz, H., Augustine, G. J. (1999): A neuronal Sec1 homolog regulates neurotransmitter release at the squid giant synapse. J. Neurosci. 18, 2923-2932.
    • (1999) J. Neurosci. , vol.18 , pp. 2923-2932
    • Dresbach, T.1    Burns, M.E.2    O'Connor, V.3    DeBello, W.M.4    Betz, H.5    Augustine, G.J.6
  • 10
    • 0032544441 scopus 로고    scopus 로고
    • Three-dimensional structure of an evolutionarily conserved N-terminal domain of syntaxin 1A
    • Fernandez, I., Ubach, J., Dulubova, I., Zhang, X., Südhof, T. C., Rizo, J. (1998): Three-dimensional structure of an evolutionarily conserved N-terminal domain of syntaxin 1A. Cell 94, 841-849.
    • (1998) Cell , vol.94 , pp. 841-849
    • Fernandez, I.1    Ubach, J.2    Dulubova, I.3    Zhang, X.4    Südhof, T.C.5    Rizo, J.6
  • 13
    • 0031567602 scopus 로고    scopus 로고
    • High-affinity binding of the yeast cis-Golgi t-SNARE, Sed5p, to wild-type and mutant Sly1p, a modulator of transport vesicle docking
    • Grabowski, R., Gallwitz, D. (1997): High-affinity binding of the yeast cis-Golgi t-SNARE, Sed5p, to wild-type and mutant Sly1p, a modulator of transport vesicle docking. FEBS Lett. 411, 169-172.
    • (1997) FEBS Lett. , vol.411 , pp. 169-172
    • Grabowski, R.1    Gallwitz, D.2
  • 14
    • 0025977037 scopus 로고
    • Eucaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase
    • Guan, K. L., Dixon, J. E. (1991): Eucaryotic proteins expressed in Escherichia coli: an improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase. Anal. Biochem. 192, 262-267.
    • (1991) Anal. Biochem. , vol.192 , pp. 262-267
    • Guan, K.L.1    Dixon, J.E.2
  • 15
    • 0030740252 scopus 로고    scopus 로고
    • Structure and conformational changes in NSF and its membrane receptor complexes visualized by quick-freeze/deep-etch electron microscopy
    • Hanson, P. I., Roth, R., Morisaki, H., Jahn, R., Heuser, J. E. (1997): Structure and conformational changes in NSF and its membrane receptor complexes visualized by quick-freeze/deep-etch electron microscopy. Cell 90, 523-535.
    • (1997) Cell , vol.90 , pp. 523-535
    • Hanson, P.I.1    Roth, R.2    Morisaki, H.3    Jahn, R.4    Heuser, J.E.5
  • 16
    • 0027938531 scopus 로고
    • Mutations in the Drosophila Rop gene suggest a function in general secretion and synaptic transmission
    • Harrison, S. D., Broadie, K., van de Goor, J., Rubin, G. M. (1994): Mutations in the Drosophila Rop gene suggest a function in general secretion and synaptic transmission. Neuron 13, 555-566.
    • (1994) Neuron , vol.13 , pp. 555-566
    • Harrison, S.D.1    Broadie, K.2    Van De Goor, J.3    Rubin, G.M.4
  • 17
    • 0027364502 scopus 로고
    • Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin
    • Hata, Y., Slaughter, C. A., Südhof. T. C. (1993): Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin. Nature 366, 347-351.
    • (1993) Nature , vol.366 , pp. 347-351
    • Hata, Y.1    Slaughter, C.A.2    Südhof, T.C.3
  • 18
    • 0028998826 scopus 로고
    • A novel ubiquitous form of munc18 interacts with multiple syntaxins
    • Hata, Y., Südhof, T. C. (1995): A novel ubiquitous form of munc18 interacts with multiple syntaxins. J. Biol. Chem. 270, 13022-13028.
    • (1995) J. Biol. Chem. , vol.270 , pp. 13022-13028
    • Hata, Y.1    Südhof, T.C.2
  • 19
    • 0030796026 scopus 로고    scopus 로고
    • SNAREs and NSF in targeted membrane fusion
    • Hay, J. C., Scheller, R. H. (1997): SNAREs and NSF in targeted membrane fusion. Curr. Opin. Cell Biol. 9, 505-512.
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 505-512
    • Hay, J.C.1    Scheller, R.H.2
  • 20
    • 0032836484 scopus 로고    scopus 로고
    • Membrane fusion and exocytosis
    • Jahn, R., Südhof, T. C. (1999): Membrane fusion and exocytosis. Annu. Rev. Biochem. 68, 863-911.
    • (1999) Annu. Rev. Biochem. , vol.68 , pp. 863-911
    • Jahn, R.1    Südhof, T.C.2
  • 21
    • 0029058496 scopus 로고
    • Distinct domains of syntaxin are required for synaptic vesicle fusion complex formation and dissociation
    • Kee, Y., Lin, R. C., Hsu, S. C., Scheller, R. H. (1995): Distinct domains of syntaxin are required for synaptic vesicle fusion complex formation and dissociation. Neuron 14, 991-998.
    • (1995) Neuron , vol.14 , pp. 991-998
    • Kee, Y.1    Lin, R.C.2    Hsu, S.C.3    Scheller, R.H.4
  • 22
    • 0029917101 scopus 로고    scopus 로고
    • Localization of synaptotagmin-binding domains on syntaxin
    • Kee, Y., Scheller, R. H. (1996): Localization of synaptotagmin-binding domains on syntaxin. J. Neurosci. 16, 1975-1981.
    • (1996) J. Neurosci. , vol.16 , pp. 1975-1981
    • Kee, Y.1    Scheller, R.H.2
  • 23
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U. K. (1970): Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 25
    • 0032432791 scopus 로고    scopus 로고
    • The Sec1p homologue Vps45p binds to the syntaxin Tlg2p
    • Nichols, B. J., Holthuis, J. C., Pelham, H. R. (1998): The Sec1p homologue Vps45p binds to the syntaxin Tlg2p. Eur. J. Cell Biol. 77, 263-268.
    • (1998) Eur. J. Cell Biol. , vol.77 , pp. 263-268
    • Nichols, B.J.1    Holthuis, J.C.2    Pelham, H.R.3
  • 26
    • 0033492872 scopus 로고    scopus 로고
    • Overexpression of cysteine-string proteins in Drosophila reveals interactions with syntaxin
    • Nie, Z., Ranjan, R., Wenniger, J. J., Hong, S. N., Bronk, P., Zinsmaier, K. E. (1999): Overexpression of cysteine-string proteins in Drosophila reveals interactions with syntaxin. J. Neurosci. 19, 10270-10279.
    • (1999) J. Neurosci. , vol.19 , pp. 10270-10279
    • Nie, Z.1    Ranjan, R.2    Wenniger, J.J.3    Hong, S.N.4    Bronk, P.5    Zinsmaier, K.E.6
  • 31
    • 0027517462 scopus 로고
    • A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion
    • Söllner, T., Bennet, M. K., Whiteheart, S. W., Scheller, R. H., Rothman, J. E. (1993): A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion. Cell 75, 409-418.
    • (1993) Cell , vol.75 , pp. 409-418
    • Söllner, T.1    Bennet, M.K.2    Whiteheart, S.W.3    Scheller, R.H.4    Rothman, J.E.5
  • 32
    • 3543096759 scopus 로고    scopus 로고
    • Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 Å resolution
    • Sutton, B., Fasshauer, D., Jahn, R., Brünger, A. T. (1998): Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 Å resolution. Nature 395, 347-353.
    • (1998) Nature , vol.395 , pp. 347-353
    • Sutton, B.1    Fasshauer, D.2    Jahn, R.3    Brünger, A.T.4
  • 33
    • 0028924613 scopus 로고
    • Molecular identification of two novel Munc-18 isoforms expressed in non-neuronal tissues
    • Tellam, J. T., McIntosh, S., James, D. E. (1995): Molecular identification of two novel Munc-18 isoforms expressed in non-neuronal tissues. J. Biol. Chem. 270, 5857-5863.
    • (1995) J. Biol. Chem. , vol.270 , pp. 5857-5863
    • Tellam, J.T.1    McIntosh, S.2    James, D.E.3
  • 34
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose filters: Procedure and some applications
    • Towbin, H., Staehelin, T., Gordon, J. (1979): Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose filters: Procedure and some applications. Proc. Natl. Acad. Sci. USA 76, 4350-4354.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 36
    • 0000040564 scopus 로고    scopus 로고
    • Syntaxin 1A interacts with multiple exocytic proteins to regulate neurotransmitter release in vivo
    • Wu, M. N., Fergestad, T., Lloyd, T. E., He, Y., Broadie, K., Bellen, H. J. (1999): Syntaxin 1A interacts with multiple exocytic proteins to regulate neurotransmitter release in vivo. Neuron 23, 593-605.
    • (1999) Neuron , vol.23 , pp. 593-605
    • Wu, M.N.1    Fergestad, T.2    Lloyd, T.E.3    He, Y.4    Broadie, K.5    Bellen, H.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.