CGRP-immunoreactive nerves in prurigo nodularis - An exploration of neurogenic inflammation

Journal of Cutaneous Pathology

Volumn 27, Issue 7, 2000, Pages 359-366

  Liang, Yong ^a   Jacobi, Henrik H ^b   Reimert, Claus M ^c   Haak Frendscho, Mary ^d   Marcusson, Jan A ^e   Johansson, Olle ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b Rigshospitalet   (Denmark)

^c DANISH BILHARZIASIS LABORATORY   (Denmark)

^d PROMEGA CORPORATION   (United States)

^e KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; TRYPTASE;

ADULT; AGED; ANTIBODY LABELING; ARTICLE; CONTROLLED STUDY; EOSINOPHIL; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOREACTIVITY; INFLAMMATORY CELL; MALE; MAST CELL; NERVE FIBER; NEUROGENIC INFLAMMATION; PROTEIN LOCALIZATION; PRURIGO; ULTRASTRUCTURE; VASODILATATION;

EID: 0033932073     PISSN: 03036987     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0560.2000.027007359.x     Document Type: Article

References (34)

1. 1. Hardaway WA. Case of multiple tumor of the skin accompanied by intense pruritus. Arch Dermatol 1880; 6: 129.
2. 2. Hyde JN. Prurigo nodularis. In: Hyde JN, Montgomery FH, eds. A practical treatise on diseases of the skin for the use of students and practitioners. Philadelphia: Lea and Febiger, 1909; 174.
3. 3. Miyachi Y, Okamoto H, Furukawa F, Imamura S. Prurigo nodularis. A possible relationship to atopy. J Dermatol 1980; 7: 281.
4. 4. Cowan MA. Neurohistological changes in prurigo nodularis. Arch Dermatol 1964; 89: 754.
5. 5. Abadía Molina F, Burrows NP, Jones RR, Terenghi G, Polak JM. Increased sensory neuropeptides in nodular prurigo: a quantitative immunohistochemical analysis. Br J Dermatol 1992; 127: 344.
6. 6. Al'Abadie MSK, Senior HJ, Bleehen SS, Gawkrodger DJ. Neuronal marker and neuropeptide studies in nodular prurigo. Eur J Dermatol 1994; 4: 154.
7. 7. Liang Y, Heilborn JD, Marcusson JA, Johansson O. Increased NGFr immunoreactive, dermal nerve fibers in prurigo nodularis. Eur J Dermatol 1996; 6: 563.
8. 8. Liang Y, Marcusson JA, Johansson O. Light and electron microscopic immunohistochemical observations of p75 nerve growth factor receptor-immunoreactive dermal nerves in prurigo nodularis. Arch Dermatol Res 1999; 291: 14.
9. 9. Liang Y, Marcusson JA, Jacobi HH, Haak-Frendscho M, Johansson O. Histamine-containing mast cells and their relationship to NGFr-immunoreactive nerves in prurigo nodularis: a reappraisal. J Cutan Pathol 1998; 25: 189.
10. 10. Johansson O, Liang Y, Marcusson JA, Reimert CM. Eosinophil cationic protein-and eosinophil-derived neurotoxin/ cosinophil protein X-immunoreactive eosinophils in prurigo nodularis. Arch Derm Res, in press, 2000.
11. 11. Johansson O, Liang Y, Heilborn JD, Marcusson JA. Langerhans cells in prurigo nodularis investigated by HLA-DR and S-100 immunofluorescence double staining. J Derm Sci 1998; 17: 24.
12. 12. Holzer P. Neurogenic vasodilatation and plasma leakage in the skin. Gen Pharmacol 1998; 30: 5.
13. 13. Merhi M, Dusting GJ, Khalil Z. CGRP and nitric oxide of neuronal origin and their involvement in neurogenic vasodilatation in rat skin microvasculature. Br J Pharmacol 1998; 123: 863.
14. 14. Vaalasti A, Suomalainen H, Rechardt L. Calcitonin gene-related peptide immunoreactivity in prurigo nodularis: a comparative study with neurodermatitis circumscripta. Br J Dermatol 1989; 120: 619.
15. 15. Johnson GD, Nogueira Araujo GM de C. A simple method for reducing the fading of immunofluorescence during microscopy. J Immunol Meth 1981; 43: 349.
16. 16. Reimert CM, Venge P, Kharazmi A, Bendtzen K. Detection of eosinophil cationic protein (ECP) by an enzyme-linked immunosorbent assay. J Immunol Meth 1991; 138: 285.
17. 8-37) on skin vasodilatation and oedema induced by stimulation of the rat saphenous nerve. BrJ Pharmacol 1993; 110: 772.
18. 18. Foreman JC. Substance P and calcitonin gene-related peptide: Effects on mast cells and in human skin. Int Archs Allergy Appl Immunol 1987; 82: 366.
19. 19. Payan DG, Levine JD, Goetzl EJ. Modulation of immunity and hypersensitivity by sensory neuropeptides. J Immunol 1984; 132: 1601.
20. 20. Brain SD, Tippins JR, Morris HR, MacIntyre I, Williams TJ. Potent vasodilator activity of calcitonin gene-related peptide in human skin. J Invest Dermatol 1986; 87: 533.
21. 21. Brain SD, Newbold P, Kajekar R. Modulation of the release and activity of neuropeptides in the microcirculation. Can J Physiol Pharmacol 1995; 73: 995.
22. 22. Piotrowski W, Foreman JC. Some effects of calcitonin gene-related peptide in human skin and on histamine release. Br J Dermatol 1986; 114: 37.
23. 23. Naukkarinen A, Harvima IT, Aalto M-L, Harvima RJ, Horsmanheimo M. Quantitative analysis of contact sites between mast cells and sensory nerves in cutaneous psoriasis and lichen planus based on a histochemical double staining technique. Arch Dermatol Res 1991; 283: 433.
24. 24. Johansson O, Han S-W, Enhamre A. Altered cutaneous innervation in psoriatic skin as revealed by PGP 9.5 immunohistochemistry. Arch Derm Res 1991; 283: 519.
25. 25. Naukkarinen A, Järvikallio A, Lakkakorpi J, Harvima IT, Harvima RJ, Horsmanheimo M. Quantitative histochemical analysis of mast cells and sensory nerves in psoriatic skin. J Pathol 1996; 180: 200.
26. 26. Reynier-Rebuffel A-M, Mathiau P, Callebert J, et al. Substance P, calcitonin gene-related peptide, and capsaicin release serotonin from cerebrovascular mast cells. Am J Physiol 1994; 267: R1421.
27. 27. Zochodne DW, Theriault M, Sharkey KA, Cheng C, Sutherland G. Peptides and neuromas: Calcitonin gene-related peptide, substance P, and mast cells in a mechanosensitive human sural neuroma. Muscle Nerve 1997; 20: 875.
28. 28. Shakhanbeh J, Abo-Galyon Y. Effects of inflammation on plasma extravasation and mast cell response in normal and denervated rat skin. Skin Pharmacol 1996; 9: 203.
29. 29. Egan CL, Viglione-Schneck MJ, Walsh LJ, et al. Characterization of unmyclinated axons uniting epidermal and dermal immune cells in primate and murine skin. J Cutan Pathol 1998; 25: 20.
30. 30. Benrath J, Eschenfelder C, Zimmerman M, Gillardon F. Calcitonin gene-related peptide, substance P and nitric oxide are involved in cutaneous inflammation following ultraviolet irradiation. Eur J Pharmacol 1995; 293: 87.
31. 31. Niizeki H, Alard P, Streilein JW. Calcitonin gene-related peptide is necessary for ultraviolet B-impaired induction of contact hypersensitivity. J Immunol 1997; 159: 5183.
32. 32. Wilsoncroft P, Gaffen Z, Reynia S, Brain SD. The modulation by nedocromil sodium of proteases released from rat peritoneal mast cells capable of degrading vasoactive intestinal peptide and calcitonin gene-related peptide. Immunopharmacology 1993; 25: 197.
33. 33. Walls AF, Brain SD, Desai A, et al. Human mast cell tryptase attenuates the vasodilator activity of calcitonin gene-related peptide. Biochem Pharmacol 1992; 43: 1243.
34. 34. Coyle AJ, Perretti F, Manzini S, Irvin CG. Cationic protein-induced sensory nerve activation: Role of substance P in airway hyperresponsiveness and plasma protein extravasation. J Clin Invest 1994; 94: 2301.