Bioavailable acyl-CoA : Cholesterol acyltransferase inhibitor with anti- peroxidative activity: Synthesis and biological activity of novel indolinyl amide and urea derivatives

Chemical and Pharmaceutical Bulletin

Volumn 48, Issue 6, 2000, Pages 817-827

  Kamiya, Shoji ^a   Shirahase, Hiroaki ^a   Yoshimi, Akihisa ^a   Nakamura, Shohei ^a   Kanda, Mamoru ^a   Matsui, Hiroshi ^a   Kasai, Masayasu ^a   Takahashi, Kenji ^a   Kurahashi, Kazuyoshi ^b  

^a Research Laboratories   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

Acyl CoA : cholesterol acyltransferase inhibitor; Anti atherosclerotic drug; Anti hyperlipidemic drug; Anti oxidant; Indoline derivative

Indexed keywords

1 BENZYL 1 [[3 (4 CHLOROPHENYL) 5 METHYL 2 BENZOFURANYL]METHYL] 3 (2,4,6 TRIFLUOROPHENYL)UREA; AMIDE; CHOLESTEROL; CHOLESTEROL ACYLTRANSFERASE INHIBITOR; N (1 ALKYL 4,6 DIMETHYLINDOLIN 7 YL) 2,2 DIMETHYLPROPANAMIDE; N (4,6 DIMETHYL 1 OCTYLINDOLIN 7 YL) 2,2 DIMETHYLPROPANAMIDE HYDROCHLORIDE; PROBUCOL; UNCLASSIFIED DRUG; UREA DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; ATHEROSCLEROSIS; BRAIN HOMOGENATE; CHOLESTEROL INTAKE; DOG; DRUG ACTIVITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HAMSTER; HYPERLIPIDEMIA; LIPID PEROXIDATION; NONHUMAN; PHARMACOPHORE; RAT;

EID: 0033923028     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.48.817     Document Type: Article

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