-
1
-
-
0032563304
-
Circulation of cholesterol between lysosomes and plasma membrane
-
Lange Y., Ye J., Steck T.L. Circulation of cholesterol between lysosomes and plasma membrane. J Biol Chem. 273:1998;18915-18922.
-
(1998)
J Biol Chem
, vol.273
, pp. 18915-18922
-
-
Lange, Y.1
Ye, J.2
Steck, T.L.3
-
2
-
-
0033583562
-
Intracellular cholesterol transport
-
Liscum L., Munn N.J. Intracellular cholesterol transport. Biochim Biophys Acta. 1438:1999;19-37.
-
(1999)
Biochim Biophys Acta
, vol.1438
, pp. 19-37
-
-
Liscum, L.1
Munn, N.J.2
-
3
-
-
0032513038
-
Characterization of a cytosolic heat-shock protein-caveolin chaperone complex. Involvement in cholesterol trafficking
-
Uittenbogaard A., Ying Y., Smart E.J. Characterization of a cytosolic heat-shock protein-caveolin chaperone complex. Involvement in cholesterol trafficking. J Biol Chem. 273:1998;6525-6532.
-
(1998)
J Biol Chem
, vol.273
, pp. 6525-6532
-
-
Uittenbogaard, A.1
Ying, Y.2
Smart, E.J.3
-
4
-
-
0030459196
-
Intracellular transport of low density lipoprotein derived free cholesterol begins at clathrin-coated pits and terminates at cell surface caveolae
-
Fielding P.E., Fielding C.J. Intracellular transport of low density lipoprotein derived free cholesterol begins at clathrin-coated pits and terminates at cell surface caveolae. Biochemistry. 35:1996;14932-14938.
-
(1996)
Biochemistry
, vol.35
, pp. 14932-14938
-
-
Fielding, P.E.1
Fielding, C.J.2
-
5
-
-
0033596725
-
Intracellular cholesterol transport in synchronized human skin fibroblasts
-
Fielding C.J., Bist A., Fielding P.E. Intracellular cholesterol transport in synchronized human skin fibroblasts. Biochemistry. 38:1999;2506-2513.
-
(1999)
Biochemistry
, vol.38
, pp. 2506-2513
-
-
Fielding, C.J.1
Bist, A.2
Fielding, P.E.3
-
6
-
-
0033962086
-
Transport of lipids from Golgi to plasma membrane is defective in Tangier disease patients and Abc1-deficient mice
-
Orso E., Broccardo C., Kaminski W.E., Bottcher A., Liebisch G., Drobnik W., Gotz A., Chambenoit O., Diederich W., Langmann T.et al. Transport of lipids from Golgi to plasma membrane is defective in Tangier disease patients and Abc1-deficient mice. Nat Genet. 23:2000;192-196.
-
(2000)
Nat Genet
, vol.23
, pp. 192-196
-
-
Orso, E.1
Broccardo, C.2
Kaminski, W.E.3
Bottcher, A.4
Liebisch, G.5
Drobnik, W.6
Gotz, A.7
Chambenoit, O.8
Diederich, W.9
Langmann, T.10
-
7
-
-
0033042826
-
Changes in membrane microdomains and caveolae constituents in multidrug-resistant cancer cells
-
Lavie Y., Fiucci G., Czarny M., Liscovitch M. Changes in membrane microdomains and caveolae constituents in multidrug-resistant cancer cells. Lipids. 34:1999;S57-63.
-
(1999)
Lipids
, vol.34
, pp. 57-63
-
-
Lavie, Y.1
Fiucci, G.2
Czarny, M.3
Liscovitch, M.4
-
8
-
-
0029804198
-
Cyclic AMP induces apolipoprotein E binding activity and promotes cholesterol efflux from a macrophage cell line to apolipoprotein acceptors
-
Smith J.D., Miyata M., Ginsberg M., Grigaux C., Shmookler E., Plump A.S. Cyclic AMP induces apolipoprotein E binding activity and promotes cholesterol efflux from a macrophage cell line to apolipoprotein acceptors. J Biol Chem. 271:1996;30647-30655.
-
(1996)
J Biol Chem
, vol.271
, pp. 30647-30655
-
-
Smith, J.D.1
Miyata, M.2
Ginsberg, M.3
Grigaux, C.4
Shmookler, E.5
Plump, A.S.6
-
9
-
-
0031036630
-
ABC1, an ATP binding cassette transporter required for phagocytosis of apoptotic cells, generates a regulated anion flux after expression in Xenopus laevis oocytes
-
Becq F., Hamon Y., Bajetto A., Gola M., Verrier B., Chimini G. ABC1, an ATP binding cassette transporter required for phagocytosis of apoptotic cells, generates a regulated anion flux after expression in Xenopus laevis oocytes. J Biol Chem. 272:1997;2695-2699.
-
(1997)
J Biol Chem
, vol.272
, pp. 2695-2699
-
-
Becq, F.1
Hamon, Y.2
Bajetto, A.3
Gola, M.4
Verrier, B.5
Chimini, G.6
-
10
-
-
0001137203
-
The class B, type I scavenger receptor promotes the selective uptake of high density lipoprotein cholesterol ethers into caveolae
-
Graf G.A., Connell P.M., van der Westhuyzen D.R., Smart E.J. The class B, type I scavenger receptor promotes the selective uptake of high density lipoprotein cholesterol ethers into caveolae. J Biol Chem. 274:1999;12043-12048.
-
(1999)
J Biol Chem
, vol.274
, pp. 12043-12048
-
-
Graf, G.A.1
Connell, P.M.2
Van Der Westhuyzen, D.R.3
Smart, E.J.4
-
11
-
-
0033548572
-
Multidrug resistance (MDR1) P-glycoprotein enhances esterification of plasma membrane cholesterol
-
Luker G.D., Nilsson K.R., Covey D.F., Piwnica-Worms D. Multidrug resistance (MDR1) P-glycoprotein enhances esterification of plasma membrane cholesterol. J Biol Chem. 274:1999;6979-6991.
-
(1999)
J Biol Chem
, vol.274
, pp. 6979-6991
-
-
Luker, G.D.1
Nilsson, K.R.2
Covey, D.F.3
Piwnica-Worms, D.4
-
12
-
-
0033515560
-
The Niemann-Pick C1 protein resides in a vesicular compartment linked to retrograde transport of multiple lysosomal cargo
-
An important breakthrough study, providing novel insight into the cell biology of NPC1 and also demonstrating NPC1's role as a general regulator of retrograde transport in the endosomal/lysosomal pathway, rather than an exclusive role in cholesterol transport per se.
-
Neufeld E.B., Wastney M., Patel S., Suresh S., Cooney A.M., Dwyer N.K., Roff C.F., Ohno K., Morris J.A., Carstea E.D.et al. The Niemann-Pick C1 protein resides in a vesicular compartment linked to retrograde transport of multiple lysosomal cargo. J Biol Chem. 274:1999;9627-9635. An important breakthrough study, providing novel insight into the cell biology of NPC1 and also demonstrating NPC1's role as a general regulator of retrograde transport in the endosomal/lysosomal pathway, rather than an exclusive role in cholesterol transport per se.
-
(1999)
J Biol Chem
, vol.274
, pp. 9627-9635
-
-
Neufeld, E.B.1
Wastney, M.2
Patel, S.3
Suresh, S.4
Cooney, A.M.5
Dwyer, N.K.6
Roff, C.F.7
Ohno, K.8
Morris, J.A.9
Carstea, E.D.10
-
13
-
-
1642454485
-
Localization of Niemann-Pick C1 protein in astrocytes: Implications for neuronal degeneration in Niemann-Pick type C disease
-
Patel S.C., Suresh S., Kumar U., Hu C.Y., Cooney A., Blanchette Mackie E.J., Neufeld E.B., Patel R.C., Brady R.O., Patel Y.C.et al. Localization of Niemann-Pick C1 protein in astrocytes: implications for neuronal degeneration in Niemann-Pick type C disease. Proc Natl Acad Sci USA. 96:1999;1657-1662.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 1657-1662
-
-
Patel, S.C.1
Suresh, S.2
Kumar, U.3
Hu, C.Y.4
Cooney, A.5
Blanchette Mackie, E.J.6
Neufeld, E.B.7
Patel, R.C.8
Brady, R.O.9
Patel, Y.C.10
-
14
-
-
0033145510
-
Late endosomal membranes rich in lysobisphosphatidic acid regulate cholesterol transport
-
••], this study emphasizes that NPC1 regulates overall retrograde transport rather than cholesterol transport per se. A role for the intra-endosomal lysobisphosphatidic acid-rich network in NPC1-mediated sorting of cholesterol is proposed.
-
••], this study emphasizes that NPC1 regulates overall retrograde transport rather than cholesterol transport per se. A role for the intra-endosomal lysobisphosphatidic acid-rich network in NPC1-mediated sorting of cholesterol is proposed.
-
(1999)
Nat Cell Biol
, vol.1
, pp. 113-118
-
-
Kobayashi, T.1
Beuchat, M.H.2
Lindsay, M.3
Frias, S.4
Palmiter, R.D.5
Sakuraba, H.6
Parton, R.G.7
Gruenberg, J.8
-
15
-
-
0033514298
-
rdNiemann-Pick C1 protein: Obligatory roles for N-terminal domains and lysosomal targeting in cholesterol mobilization
-
rdNiemann-Pick C1 protein: obligatory roles for N-terminal domains and lysosomal targeting in cholesterol mobilization. Proc Natl Acad Sci USA. 96:1999;805-810.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 805-810
-
-
Watari, H.1
Blanchette-Mackie, E.J.2
Dwyer, N.K.3
Glick, J.M.4
Patel, S.5
Neufeld, E.B.6
Brady, R.O.7
Pentchev, P.G.8
Strauss, J.F.9
-
16
-
-
0033618338
-
Mutations in the leucine zipper motif and sterol-sensing domain inactivate the Niemann-Pick C1 glycoprotein
-
Watari H., Blanchette-Mackie E.J., Dwyer N.K., Watari M., Neufeld E.B., Patel S., Pentchev P.G., Strauss J.F. Jr. Mutations in the leucine zipper motif and sterol-sensing domain inactivate the Niemann-Pick C1 glycoprotein. J Biol Chem. 274:1999;21861-21866.
-
(1999)
J Biol Chem
, vol.274
, pp. 21861-21866
-
-
Watari, H.1
Blanchette-Mackie, E.J.2
Dwyer, N.K.3
Watari, M.4
Neufeld, E.B.5
Patel, S.6
Pentchev, P.G.7
Strauss, J.f.jr.8
-
17
-
-
0034719404
-
Mobilization of late-endosomal cholesterol is inhibited by Rab guanine nucleotide dissociation inhibitor
-
Holtta-Vuori M., Maatta J., Ullrich O., Kuismanen E., Ikonen E. Mobilization of late-endosomal cholesterol is inhibited by Rab guanine nucleotide dissociation inhibitor. Curr Biol. 10:2000;95-98.
-
(2000)
Curr Biol
, vol.10
, pp. 95-98
-
-
Holtta-Vuori, M.1
Maatta, J.2
Ullrich, O.3
Kuismanen, E.4
Ikonen, E.5
-
18
-
-
0034635356
-
Role of Niemann-Pick type C1 protein in intracellular trafficking of low density lipoprotein-derived cholesterol
-
In contrast to existing views, this study suggests that NPC1 is involved in regulating recycling of plasma-membrane-derived cholesterol, rather than egression of cholesterol, following hydrolysis of LDL-mediated cholesterol delivery. The latter reaches the cell surface, and it is the subsequently reinternalized cholesterol fraction that depends on NPC1 for recycling. Accordingly, NPC1 may discriminate between different cholesterol pools.
-
Cruz J.C., Shigeki S., Yu C., Chang T-Y. Role of Niemann-Pick type C1 protein in intracellular trafficking of low density lipoprotein-derived cholesterol. J Biol Chem. 275:2000;4013-4021. In contrast to existing views, this study suggests that NPC1 is involved in regulating recycling of plasma-membrane-derived cholesterol, rather than egression of cholesterol, following hydrolysis of LDL-mediated cholesterol delivery. The latter reaches the cell surface, and it is the subsequently reinternalized cholesterol fraction that depends on NPC1 for recycling. Accordingly, NPC1 may discriminate between different cholesterol pools.
-
(2000)
J Biol Chem
, vol.275
, pp. 4013-4021
-
-
Cruz, J.C.1
Shigeki, S.2
Yu, C.3
Chang, T.-Y.4
-
19
-
-
0033959713
-
ATPase-defective mammalian VPS4 localizes to aberrant endosomes and impairs cholesterol trafficking
-
Bishop N., Woodman P. ATPase-defective mammalian VPS4 localizes to aberrant endosomes and impairs cholesterol trafficking. Mol Biol Cell. 11:2000;227-239.
-
(2000)
Mol Biol Cell
, vol.11
, pp. 227-239
-
-
Bishop, N.1
Woodman, P.2
-
20
-
-
0032931988
-
Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles
-
Rodal S.K., Skretting G., Garred Ø., Vilhardt F., Van Deurs B., Sandvig K. Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles. Mol Biol Cell. 10:1999;961-974.
-
(1999)
Mol Biol Cell
, vol.10
, pp. 961-974
-
-
Rodal, S.K.1
Skretting, G.2
Garred Ø3
Vilhardt, F.4
Van Deurs, B.5
Sandvig, K.6
-
21
-
-
0033535989
-
Acute cholesterol depletion inhibits clathrin-coated pit budding
-
Subtil A., Gaidarov I., Kobylarz K., Lampson M.A., Keen J.H., McGraw T.E. Acute cholesterol depletion inhibits clathrin-coated pit budding. Proc Natl Acad Sci USA. 96:1999;6775-6780.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 6775-6780
-
-
Subtil, A.1
Gaidarov, I.2
Kobylarz, K.3
Lampson, M.A.4
Keen, J.H.5
McGraw, T.E.6
-
22
-
-
0032541423
-
Cholesterol-dependent retention of GPI-anchored proteins in endosomes
-
Mayor S., Sabharanjak S., Maxfield F.R. Cholesterol-dependent retention of GPI-anchored proteins in endosomes. EMBO J. 17:1998;4626-4638.
-
(1998)
EMBO J
, vol.17
, pp. 4626-4638
-
-
Mayor, S.1
Sabharanjak, S.2
Maxfield, F.R.3
-
23
-
-
0033792318
-
Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles
-
Thiele C., Hannah M.J., Fahrenholz F., Huttner W.B. Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles. Nat Cell Biol. 2:2000;42-49.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 42-49
-
-
Thiele, C.1
Hannah, M.J.2
Fahrenholz, F.3
Huttner, W.B.4
-
24
-
-
0033203501
-
Cholesterol modulates membrane traffic along the endocytic pathway in sphingolipid-storage diseases
-
This work elegantly demonstrates the role of cholesterol as the common denominator in sphingolipid storage in fibroblasts from ten different storage diseases. Implicitly, this study confirms the dominant role of cholesterol in modulating the recycling of both (sphingo)lipids and proteins.
-
Puri V., Watanabe R., Dominguez M., Sun X., Wheatley C.L., Marks D.L., Pagano R.E. Cholesterol modulates membrane traffic along the endocytic pathway in sphingolipid-storage diseases. Nat Cell Biol. 1:1999;386-388. This work elegantly demonstrates the role of cholesterol as the common denominator in sphingolipid storage in fibroblasts from ten different storage diseases. Implicitly, this study confirms the dominant role of cholesterol in modulating the recycling of both (sphingo)lipids and proteins.
-
(1999)
Nat Cell Biol
, vol.1
, pp. 386-388
-
-
Puri, V.1
Watanabe, R.2
Dominguez, M.3
Sun, X.4
Wheatley, C.L.5
Marks, D.L.6
Pagano, R.E.7
-
25
-
-
0033546958
-
Broad screening test for sphingolipid-storage diseases
-
Chen C.S., Patterson M.C., Wheatley C.L., O'Brien J.F., Pagano R.E. Broad screening test for sphingolipid-storage diseases. Lancet. 354:1999;901-905.
-
(1999)
Lancet
, vol.354
, pp. 901-905
-
-
Chen, C.S.1
Patterson, M.C.2
Wheatley, C.L.3
O'Brien, J.F.4
Pagano, R.E.5
-
26
-
-
0031852648
-
(Glyco)sphingolipids are sorted in sub-apical compartments in HepG2 cells: A role for non-Golgi-related intracellular sites in the polarized distribution of (glyco)sphingolipids
-
van I., Jzendoorn S.C.D., Hoekstra D. (Glyco)sphingolipids are sorted in sub-apical compartments in HepG2 cells: a role for non-Golgi-related intracellular sites in the polarized distribution of (glyco)sphingolipids. J Cell Biol. 142:1998;683-696.
-
(1998)
J Cell Biol
, vol.142
, pp. 683-696
-
-
Van, I.1
Jzendoorn, S.C.D.2
Hoekstra, D.3
-
27
-
-
0032820934
-
Internalization and sorting of plasma membrane sphingolipid analogues in differentiating oligodendrocytes
-
Watanabe R., Asakura K., Rodriguez M., Pagano R.E. Internalization and sorting of plasma membrane sphingolipid analogues in differentiating oligodendrocytes. J Neurochem. 73:1999;1375-1383.
-
(1999)
J Neurochem
, vol.73
, pp. 1375-1383
-
-
Watanabe, R.1
Asakura, K.2
Rodriguez, M.3
Pagano, R.E.4
-
28
-
-
0030949124
-
Functional rafts in cell membranes
-
Simons K., Ikonen E. Functional rafts in cell membranes. Nature. 387:1997;569-572.
-
(1997)
Nature
, vol.387
, pp. 569-572
-
-
Simons, K.1
Ikonen, E.2
-
29
-
-
0345363228
-
Electrospray ionization tandem mass spectrometry (ESI-MS/MS) analysis of the lipid molecular species composition of yeast subcellular membranes reveals acyl chain-based sorting/remodeling of distinct molecular species en route to the plasma membrane
-
Schneiter R., Brügger B., Sandhoff R., Zellnig G., Leber A., Lampl M., Athenstaedt K., Hrastnik C., Eder S., Daum G.et al. Electrospray ionization tandem mass spectrometry (ESI-MS/MS) analysis of the lipid molecular species composition of yeast subcellular membranes reveals acyl chain-based sorting/remodeling of distinct molecular species en route to the plasma membrane. J Cell Biol. 146:1999;741-754.
-
(1999)
J Cell Biol
, vol.146
, pp. 741-754
-
-
Schneiter, R.1
Brügger, B.2
Sandhoff, R.3
Zellnig, G.4
Leber, A.5
Lampl, M.6
Athenstaedt, K.7
Hrastnik, C.8
Eder, S.9
Daum, G.10
-
30
-
-
0344791683
-
Endocytic sorting of lipid analogues differing solely in the chemistry of their hydrophobic tails
-
Exploiting the partitioning of lipid probes into membrane domains of distinct fluidity, they were used to define the molecular parameters (which are correlated to membrane biophysical properties) that determine the sorting of lipids and lipid-attached compounds in eukaryotic cells. The overall findings are consistent with the effect of membrane rigidity (also accomplished by modulating the cellular pool of cholesterol) on regulating recycling versus endosomal/lysosomal trafficking pathways.
-
Mukherjee S., Soe T.T., Maxfield F.R. Endocytic sorting of lipid analogues differing solely in the chemistry of their hydrophobic tails. J Cell Biol. 144:1999;1271-1284. Exploiting the partitioning of lipid probes into membrane domains of distinct fluidity, they were used to define the molecular parameters (which are correlated to membrane biophysical properties) that determine the sorting of lipids and lipid-attached compounds in eukaryotic cells. The overall findings are consistent with the effect of membrane rigidity (also accomplished by modulating the cellular pool of cholesterol) on regulating recycling versus endosomal/lysosomal trafficking pathways.
-
(1999)
J Cell Biol
, vol.144
, pp. 1271-1284
-
-
Mukherjee, S.1
Soe, T.T.2
Maxfield, F.R.3
-
31
-
-
0031036751
-
Changes in the spectral properties of a plasma membrane lipid analog during the first seconds of endocytosis in living cells
-
Chen C.S., Martin O.C., Pagano R.E. Changes in the spectral properties of a plasma membrane lipid analog during the first seconds of endocytosis in living cells. Biophys J. 72:1997;37-50.
-
(1997)
Biophys J
, vol.72
, pp. 37-50
-
-
Chen, C.S.1
Martin, O.C.2
Pagano, R.E.3
-
32
-
-
0030844101
-
Conversion of dihydroceramide to ceramide occurs at the cytosolic face of the endoplasmic reticulum
-
Michel C., van Echten-Deckert G. Conversion of dihydroceramide to ceramide occurs at the cytosolic face of the endoplasmic reticulum. FEBS Lett. 416:1997;153-155.
-
(1997)
FEBS Lett
, vol.416
, pp. 153-155
-
-
Michel, C.1
Van Echten-Deckert, G.2
-
33
-
-
0033593788
-
Genetic evidence for ATP-dependent endoplasmic reticulum-to-Golgi apparatus trafficking of ceramide for sphingomyelin synthesis in Chinese hamster ovary cells
-
In a mutant cell line defective in SM biosynthesis, an energy-dependent and energy-independent transport step for transport of ceramide from ER to Golgi is demonstrated. Protein transport in these cells is not impaired, raising intriguing questions about the mechanism of ceramide-mediated transport and energy-(in)dependent steps of the common precursor (ceramide) in the biosynthesis of sphingomyelin and glucosylceramide.
-
Fukasawa M., Nishijima M., Hanada K. Genetic evidence for ATP-dependent endoplasmic reticulum-to-Golgi apparatus trafficking of ceramide for sphingomyelin synthesis in Chinese hamster ovary cells. J Cell Biol. 144:1999;673-685. In a mutant cell line defective in SM biosynthesis, an energy-dependent and energy-independent transport step for transport of ceramide from ER to Golgi is demonstrated. Protein transport in these cells is not impaired, raising intriguing questions about the mechanism of ceramide-mediated transport and energy-(in)dependent steps of the common precursor (ceramide) in the biosynthesis of sphingomyelin and glucosylceramide.
-
(1999)
J Cell Biol
, vol.144
, pp. 673-685
-
-
Fukasawa, M.1
Nishijima, M.2
Hanada, K.3
-
34
-
-
0032143958
-
Ceramide transport from endoplasmic reticulum to Golgi apparatus is not vesicle-mediated
-
Kok J.W., Babia T., Klappe K., Egea G., Hoekstra D. Ceramide transport from endoplasmic reticulum to Golgi apparatus is not vesicle-mediated. Biochem J. 333:1998;779-786.
-
(1998)
Biochem J
, vol.333
, pp. 779-786
-
-
Kok, J.W.1
Babia, T.2
Klappe, K.3
Egea, G.4
Hoekstra, D.5
-
35
-
-
0032553324
-
Differential effects of sphingomyelin hydrolysis and cholesterol transport of oxysterol-binding protein phosphorylation and Golgi localization
-
Ridgway N.D., Lagace T.A., Cook H.W., Byers D.M. Differential effects of sphingomyelin hydrolysis and cholesterol transport of oxysterol-binding protein phosphorylation and Golgi localization. J Biol Chem. 273:1998;31621-31628.
-
(1998)
J Biol Chem
, vol.273
, pp. 31621-31628
-
-
Ridgway, N.D.1
Lagace, T.A.2
Cook, H.W.3
Byers, D.M.4
-
36
-
-
0033529760
-
A vital role for glycosphingolipid synthesis during development and differentiation
-
Yamashita T., Wada R., Sasaki T., Deng C., Bierfreund U., Sandhoff K., Proia R.L. A vital role for glycosphingolipid synthesis during development and differentiation. Proc Natl Acad Sci USA. 96:1999;9142-9147.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 9142-9147
-
-
Yamashita, T.1
Wada, R.2
Sasaki, T.3
Deng, C.4
Bierfreund, U.5
Sandhoff, K.6
Proia, R.L.7
-
37
-
-
0033607680
-
Glycosphingolipids are not essential for formation of detergent-resistant membrane rafts in melanoma cells
-
This study suggests that the behavior of the microdomain membrane phase rather than the presence of specific glycosphingolipids, dictates raft-like functioning in sorting and (kinetics of) transport.
-
Ostermeyer A.G., Beckrich B.T., Ivarson K.A., Grove K.E., Brown D.A. Glycosphingolipids are not essential for formation of detergent-resistant membrane rafts in melanoma cells. J Biol Chem. 274:1999;34459-34466. This study suggests that the behavior of the microdomain membrane phase rather than the presence of specific glycosphingolipids, dictates raft-like functioning in sorting and (kinetics of) transport.
-
(1999)
J Biol Chem
, vol.274
, pp. 34459-34466
-
-
Ostermeyer, A.G.1
Beckrich, B.T.2
Ivarson, K.A.3
Grove, K.E.4
Brown, D.A.5
-
38
-
-
0033958904
-
Caveolar structure and protein sorting are maintained in NIH 3T3 cells independent of glycosphingolipid depletion
-
Shu L., Lee L., Chang Y., Holzman L.B., Edwards C.A., Shelden E., Shayman J.A. Caveolar structure and protein sorting are maintained in NIH 3T3 cells independent of glycosphingolipid depletion. Arch Biochem Biophys. 373:2000;83-90.
-
(2000)
Arch Biochem Biophys
, vol.373
, pp. 83-90
-
-
Shu, L.1
Lee, L.2
Chang, Y.3
Holzman, L.B.4
Edwards, C.A.5
Shelden, E.6
Shayman, J.A.7
-
39
-
-
0033594934
-
Quantitative analysis of phospholipids in functionally important membrane domains from RBL-2H3 mast cells using tandem high-resolution mass spectrometry
-
Fridriksson E.K., Shipkova P.A., Sheets E.D., Holowka D., Baird B., McLafferty F.W. Quantitative analysis of phospholipids in functionally important membrane domains from RBL-2H3 mast cells using tandem high-resolution mass spectrometry. Biochemistry. 38:1999;8056-8063.
-
(1999)
Biochemistry
, vol.38
, pp. 8056-8063
-
-
Fridriksson, E.K.1
Shipkova, P.A.2
Sheets, E.D.3
Holowka, D.4
Baird, B.5
McLafferty, F.W.6
-
40
-
-
0031750335
-
Lipid domain structure of the plasma membrane revealed by patching of membrane components
-
Harder T., Scheiffele P., Verkader P., Simons K. Lipid domain structure of the plasma membrane revealed by patching of membrane components. J Cell Biol. 141:1998;929-942.
-
(1998)
J Cell Biol
, vol.141
, pp. 929-942
-
-
Harder, T.1
Scheiffele, P.2
Verkader, P.3
Simons, K.4
-
41
-
-
0032859986
-
Exogenous administration of gangliosides displaces GPI-anchored proteins from lipid microdomains in living cells
-
Simons M., Friedrichson T., Schulz J.B., Pitto M., Masserini M., Kurzchalia T.V. Exogenous administration of gangliosides displaces GPI-anchored proteins from lipid microdomains in living cells. Mol Biol Cell. 10:1999;3187-3196.
-
(1999)
Mol Biol Cell
, vol.10
, pp. 3187-3196
-
-
Simons, M.1
Friedrichson, T.2
Schulz, J.B.3
Pitto, M.4
Masserini, M.5
Kurzchalia, T.V.6
-
42
-
-
0033573083
-
Functionally different GPI proteins are organized in different domains on the neuronal surface
-
Madore N., Smith K.L., Graham C.H., Jen A., Brady K., Hall S., Morris R. Functionally different GPI proteins are organized in different domains on the neuronal surface. EMBO J. 18:1999;6917-6926.
-
(1999)
EMBO J
, vol.18
, pp. 6917-6926
-
-
Madore, N.1
Smith, K.L.2
Graham, C.H.3
Jen, A.4
Brady, K.5
Hall, S.6
Morris, R.7
-
43
-
-
0032509356
-
HakomoriSeparation of 'glycosphingolipid signaling domain' from caveolin-containing membrane fraction in mouse melanoma B16 cells and its role in cell adhesion coupled with signaling
-
Iwabuchi K., Handa K. HakomoriSeparation of 'glycosphingolipid signaling domain' from caveolin-containing membrane fraction in mouse melanoma B16 cells and its role in cell adhesion coupled with signaling. J Biol Chem. 272:1998;33766-33773.
-
(1998)
J Biol Chem
, vol.272
, pp. 33766-33773
-
-
Iwabuchi, K.1
Handa, K.2
-
44
-
-
0345130002
-
Maturation of the axonal plasma membrane requires upregulation of sphingomyelin synthesis and information of protein-lipid complexes
-
A fascinating study that shows that the level of sphingomyelin synthesis correlates with 'raft' formation and the subsequent sorting and targeting of a GPI-anchored protein and a ganglioside. The latter two are targeted to the ('apical') axonal plasma membrane during a late developmental stage during neuronal maturation. It can be inferred that sphingomyelin and cholesterol induce raft biogenesis in this case, whereas a role for glycosphingolipids in raft assembly and stability is rather unlikely.
-
Ledesma M.D., Brügger B., Bunning C., Wieland F.T., Dotti C.G. Maturation of the axonal plasma membrane requires upregulation of sphingomyelin synthesis and information of protein-lipid complexes. EMBO J. 18:1999;1761-1771. A fascinating study that shows that the level of sphingomyelin synthesis correlates with 'raft' formation and the subsequent sorting and targeting of a GPI-anchored protein and a ganglioside. The latter two are targeted to the ('apical') axonal plasma membrane during a late developmental stage during neuronal maturation. It can be inferred that sphingomyelin and cholesterol induce raft biogenesis in this case, whereas a role for glycosphingolipids in raft assembly and stability is rather unlikely.
-
(1999)
EMBO J
, vol.18
, pp. 1761-1771
-
-
Ledesma, M.D.1
Brügger, B.2
Bunning, C.3
Wieland, F.T.4
Dotti, C.G.5
-
46
-
-
0030845928
-
Sphingolipid transport to the apical plasma membrane in human hepatoma cells is controlled by PKC and PKA activity. A correlation with cell polarity in HepG2 cells
-
Zegers M.M.P., Hoekstra D. Sphingolipid transport to the apical plasma membrane in human hepatoma cells is controlled by PKC and PKA activity. A correlation with cell polarity in HepG2 cells. J Cell Biol. 138:1997;307-321.
-
(1997)
J Cell Biol
, vol.138
, pp. 307-321
-
-
Zegers, M.M.P.1
Hoekstra, D.2
-
47
-
-
0034016431
-
Polarized sphingolipid transport from the subapical compartment changes during cell polarity development
-
van I., Jzendoorn S.C.D., Hoekstra D. Polarized sphingolipid transport from the subapical compartment changes during cell polarity development. Mol Biol Cell. 11:2000;1093-1101.
-
(2000)
Mol Biol Cell
, vol.11
, pp. 1093-1101
-
-
Van, I.1
Jzendoorn, S.C.D.2
Hoekstra, D.3
-
48
-
-
0033044626
-
Transcytosis of immunoglobulin A in the mouse enterocyte occurs through glycolipid raft- And rab17-containing compartments
-
Hansen G.H., Niels-Christiansen L.L., Immerdal L., Hunziker W., Kenny A.J., Danielsen E.M. Transcytosis of immunoglobulin A in the mouse enterocyte occurs through glycolipid raft- and rab17-containing compartments. Gastroenterology. 116:1999;610-622.
-
(1999)
Gastroenterology
, vol.116
, pp. 610-622
-
-
Hansen, G.H.1
Niels-Christiansen, L.L.2
Immerdal, L.3
Hunziker, W.4
Kenny, A.J.5
Danielsen, E.M.6
-
49
-
-
0032830851
-
Polarized sphingolipid transport from the subapical compartment: Evidence for distinct sphingolipid domains
-
van I., Jzendoorn S.C.D., Hoekstra D. Polarized sphingolipid transport from the subapical compartment: evidence for distinct sphingolipid domains. Mol Biol Cell. 10:1999;3449-3461.
-
(1999)
Mol Biol Cell
, vol.10
, pp. 3449-3461
-
-
Van, I.1
Jzendoorn, S.C.D.2
Hoekstra, D.3
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