Immunohistochemical detection of K-sam protein in stomach cancer

Clinical Cancer Research

Volumn 2, Issue 8, 1996, Pages 1373-1381

  Hattori, Yutaka ^a   Itoh, Hiroshi ^a   Uchino, Shinya ^a   Hosokawa, Kouichi ^b   Ochiai, Atsushi ^a   Ino, Yoshinori ^a   Ishii, Hideshi ^a   Sakamoto, Hiromi ^a   Yamaguchi, Naohito ^a   Yanagihara, Kazuyoshi ^c   Hirohashi, Setsuo ^a   Sugimura, Takashi ^a   Terada, Masaaki ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b NATIONAL CANCER CENTER HOSPITAL   (Japan)

^c HIROSHIMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDIC FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR;

ANTIGEN EXPRESSION; ARTICLE; CANCER GROWTH; CELL ISOLATION; CHEMICAL REACTION; FIBROBLAST; FLOW CYTOMETRY; GENE AMPLIFICATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; SIGNAL DETECTION; STOMACH CANCER;

AMINO ACID SEQUENCE; GENE AMPLIFICATION; HUMANS; IMMUNOHISTOCHEMISTRY; MOLECULAR SEQUENCE DATA; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 2; RECEPTORS, FIBROBLAST GROWTH FACTOR; STOMACH NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 9544251380     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Parkin, D. M., Pisani, P. E., and Ferlay, J. Estimates of the worldwide incidence of 18 major cancers in 1985. Int J. Cancer, 54: 594-606, 1993.
2. Hirohashi, S., and Sugimura, T. Genetic alterations in human gastric cancer. Cancer Cells (Cold Spring Harbor), 3: 49-52, 1991.
3. Sugano, H., Nakamura, K., and Kato, Y. Pathological studies of human gastric cancer. Acta Pathol Jpn., 32: 329-347, 1982.
4. Maruyama, K. Results of surgery correlated with staging. In: P. E. Preece, A. Cuschieri, and S. M. Wellwood (eds.), Cancer of the Stomach, pp. 145-163. Orlando, FL: Grune & Stratton, 1986.
5. Nakatani, H., Tahara, E., Yoshida, T., Sakamoto, H., Suzuki, T., Watanabe, H., Sekiguchi, M., Kaneko, Y., Sakurai, M., Terada, M., and Sugimura, T Detection of amplified DNA sequences in gastric cancers by aDNA renaturation method in gel. Jpn, J. Cancer Res , 77: 849-853, 1986.
6. Nakatani, H., Sakamoto, H., Yoshida, T., Yokota, J., Tahara, E., Sugimura, T., and Terada, M. Isolation of an amplified DNA sequence in stomach cancer. Jpn. J. Cancer Res., 81: 707-710, 1990.
7. Hattori, Y., Odagiri, H., Nakatani, H., Miyagawa, K., Naito, K., Sakamoto, H., Katoh, O., Yoshida, T., Sugimura, T., and Terada, M. K-sam, an amplified gene in stomach cancer, is a member of the heparin-binding growth factor receptor genes. Proc. Natl. Acad. Sci. USA, 87: 5983-5987, 1990
8. Jaye, M., Schlessinger, J., and Dionne, C A Fibroblast growth factor receptor tyrosine kinases. molecular analysis and signal transduction. Biochim. Biophys. Acta, 1135: 185-199, 1992.
9. Johnson, D. E., and Williams, L. T. Structural and functional diversity in the FGF receptor multigene family. Adv. Cancer Res., 60: 1-41, 1993.
10. Miki, T., Fleming, T. P., Bottaro, D. P., Rubin, J. S., Ron, D., and Aaronson, S. A. Expression cDNA cloning of the KGF receptor by creation of a transforming autocrine loop. Science (Washington DC), 251: 72-75, 1991.
11. Miki, T., Bottaro, D. P., Fleming, T. P., Smith, C. L., Burgess, W H., Chen, A. M-L., and Aaronson, S. A. Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene. Proc. Natl Acad. Sci. USA, 89: 246-250, 1992.
12. Itoh, H., Hattori, Y., Sakamoto, H., Ishii, H., Kishi, T., Sasaki, H., Yoshida, T., Koono, M., Sugimura, T., and Terada, M. Preferential alternative splicing in cancer generates a K-sam messenger RNA with higher transforming activity. Cancer Res , 54: 3237-3241, 1994.
13. Sekiguchi, M., Sakakibara, K., and Fujii, G. Establishment of cultured cell lines derived from a human gastric carcinoma. Jpn. J. Exp. Med., 48: 61-68, 1978.
14. Yanagihara, K., Seyama, T., Tsumuraya, M., Kamada, N., and Yokoro, K. Establishment and characterization of human signet-ring cell gastric carcinoma cell lines with amplification of the c-myc oncogene. Cancer Res., 51: 381-386, 1991.
15. Ishii, H., Hattori, Y., Itoh, H., Kishi, T., Yoshida, T., Sakamoto, H., Oh, H , Yoshida, S., Sugimura, T., and Terada, M. Preferential expression of the third immunoglobulin-like domain of K-sam product provides keratinocyte growth factor-dependent growth in carcinoma cell lines. Cancer Res., 54: 518-522, 1994.
16. Ishii, H., Yoshida, T., Oh, H., Yoshida, S., and Terada, M. A truncated K-sam product lacking the distal carboxyl-terminal portion provides a reduced level of autophosphorylation and greater resistance against induction of differentiation. Mol. Cell. Biol., 15: 3664-3671, 1995.
17. Japanese Research Society for Gastric Cancer. Part I (clinical, surgical, and conclusive findings) and II (histological findings). In: Japanese Classification of Gastric Carcinoma, 1 st English ed., pp. 2-65. Tokyo: Kanehara, 1995.
18. Borrman, R. Geschwulste des Magens und Duodenums. In: F. Henske and O. Lubarsch (eds.), Handbuch der Speziellen Pathologischen Anatomie und Histologie, pp. 864-871 Berlin: Julius Springer, 1926.
19. Sato, Y., Mukai, K., Watanabe, S., Goto, M., and Shimosato, Y. The AMeX method: a simplified technique of tissue-processing and paraffin-embedding with improved preservation of antigens for immunostaining. Am. J. Pathol., 125: 431-435, 1986.
20. Hattori, Y., Odagiri, H., Katoh, O., Sakamoto, H., Morita, T., Shimotohno, K., Tobinai, K., Sugimura, T., and Terada, M. K-sam-related gene, N-sam, encodes fibroblast growth factor receptor and is expressed in T-lymphocytic tumors. Cancer Res., 52: 3367-3371, 1992.
21. Tsuda, H., Shimosato, Y., Upton, M. P., Yokota, J., Terada, M., Ohira, M., Sugimura, T., and Hirohashi, S. Retrospective study on amplification of N-myc and c-myc genes in pediatric solid tumors and its association with prognosis and tumor differentiation. Lab. Invest., 59: 321-327, 1988.
22. Kaplan, E. L., and Meier. P. Nonparametric estimation from incomplete observations. J. Am. Stat. Assoc., 55: 457-481, 1958. .
23. Kishi, T., Yoshida, T., and Terada, M. A soluble form of K-saml FGFR2 protein in the culture medium of human gastric cancer cells. Biochem. Biophys. Res. Commun., 202: 1387-1394, 1994.
24. Katoh, O., Hattori, Y., Sasaki, H., Sakamoto, H., Fujimoto, K., Fujii, T., Sugimura, T., and Terada, M. Isolation of the complementary DNA encoding a mouse heparin-binding growth factor receptor with the use of a unique kinase insert sequence. Cancer Res., 53: 1136-1141, 1993.
25. Katoh, M., Hattori, Y., Sasaki, H., Tanaka, M., Sugano, K., Yazaki, Y., Sugimura, T., and Terada, M. K-sam gene encodes secreted as well as transmembrane receptor tyrosine kinase. Proc. Natl. Acad. Sci. USA, 89: 2960-2964, 1992.
26. Yokota, J., Yamamoto, T., Miyajima, N , Toyoshima, K., Nomura, N., Sakamoto, H., Yoshida, T., Terada, M., and Sugimura, T. Genetic alterations of the c-erbB-2 oncogene occur frequently in tubular adenocarcinoma of the stomach and are often accompanied by amplification of the v-erbA homologue. Oncogene, 2: 283-287, 1988.
27. Finch, P. W., Rubin, J. S., Miki, T., Ron, D., and Aaronson, S. A. Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth. Science (Washington DC), 245: 752-755. 1989.