The death domain of tumor necrosis factor receptor 1 is necessary but not sufficient for Golgi retention of the receptor and mediates receptor desensitization

Laboratory Investigation

Volumn 80, Issue 8, 2000, Pages 1185-1194

  Gaeta, Mary Lou ^a   Johnson, David R ^a   Kluger, Martin S ^a   Pober, Jordan S ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TUMOR NECROSIS FACTOR RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2; UNCLASSIFIED DRUG;

ARTICLE; CELL DEATH; CELL MEMBRANE; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOTHELIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION;

EID: 0033898110     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: 10.1038/labinvest.3780126     Document Type: Article

References (39)

1. A novel cytoplasmic domain of the p55 tumor necrosis factor receptor initiates the neutral sphingomyelinase pathway
2. The tumor necrosis factor ligand and receptor families
3. Cell surface trafficking of Fas: A rapid mechanism of p53-mediated apoptosis
4. Identification of an inducible endothelial-leukocyte adhesion molecule
5. Self-association of the 'death domains' of the p55 tumor necrosis factor (TNF) receptor and Fas/APO1 prompts signaling for TNF and Fas/APO1 effects
6. Disparate localization of 55-kd and 75-kd tumor necrosis factor receptors in human endothelial cells
7. Cytoplasmic truncation of the p55 tumour necrosis factor (TNF) receptor abolishes signalling, but not induced shedding of the receptor
8. Vascular cell adhesion molecule-1 mediates lymphocyte adherence to cytokine-activated cultured human endothelial cells
9. Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95
10. Contenders in FasL/TNF death signaling
11. The death domain: A module shared by proteins with diverse cellular functions
12. Culture of vascular endothelium
13. Overexpression of the p80 TNF receptor leads to TNF-dependent apoptosis, nuclear factor-kappa B activation, and c-Jun kinase activation
14. TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex
15. TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways
16. The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation
17. Prevention of constitutive TNF receptor 1 signaling by silencer of death domains
18. TNF recruits TRADD to the plasma membrane but not the trans-Golgi network, the principal subcellular location of TNF-R1
19. Activation and homologous desensitization of human endothelial cells by CD40 ligand, tumor necrosis factor, and interleukin 1
20. A death-domain-containing receptor that mediates apoptosis
21. Inhibition of tumor necrosis factor (TNF)-mediated NF-kappa B activation by selective blockade of the human 55-kDa TNF receptor
22. Function of the p55 tumor necrosis factor receptor 'death domain' mediated by phosphatidylcholine-specific phospholipase C
23. Tumor necrosis factor alpha (TNF-alpha)-induced cell adhesion to human endothelial cells is under dominant control of one TNF receptor type, TNF-R55
24. The interferon-inducible p202 protein as a modulator of transcription: Inhibition of NF-kappa B, c-Fos, and c-Jun activities
25. Caveolins, a family of scaffolding proteins for organizing 'preassembled signaling complexes' at the plasma membrane
26. Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes
27. Systematic mutational analysis of the death domain of the tumor necrosis factor receptor 1-associated protein TRADD
28. Structural basis for self-association and receptor recognition of human TRAF2
29. Two distinct monokines, interleukin 1 and tumor necrosis factor, each independently induce biosynthesis and transient expression of the same antigen on the surface of cultured human vascular endothelial cells
30. Cytokines and endothelial cell biology
31. Activation of cultured human endothelial cells by recombinant lymphotoxin: Comparison with tumor necrosis factor and interleukin 1 species
32. An inducible endothelial cell surface glycoprotein mediates melanoma adhesion
33. Tumor necrosis factor activates human endothelial cells through the p55 tumor necrosis factor receptor but the p75 receptor contributes to activation at low tumor necrosis factor concentration
34. The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death
35. Monokine-induced gene expression of a human endothelial cell-derived neutrophil chemotactic factor
36. Monocyte chemotactic protein gene expression by cytokine-treated human fibroblasts and endothelial cells
37. A novel domain within the 55 kd TNF receptor signals cell death
38. Tumor necrosis factor receptor signaling. A dominant negative mutation suppresses the activation of the 55-kDa tumor necrosis factor receptor
39. Two TNF receptors