Drug target validation: Lethal infection blocked by inducible peptide

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 2, 2000, Pages 783-786

  Tao, Jianshi ^a   Wendler, Philip ^a   Connelly, Gene ^a   Lim, Audrey ^a   Zhang, Jiansu ^a   King, Megan ^a   Li, Tongchuan ^a   Silverman, Jared A ^a   Schimmel, Paul R ^b   Tally, Francis P ^a  

^a CUBIST PHARMACEUTICALS INC   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANHYDROTETRACYCLINE; ANTIINFECTIVE AGENT; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; PROLINE TRANSFER RNA SYNTHETASE; SYNTHETASE; SYNTHETIC PEPTIDE; TRANSFER RNA; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; AMINOACYLATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL INFECTION; CONTROLLED STUDY; DNA SEQUENCE; DRUG BINDING SITE; DRUG DETERMINATION; DRUG TARGETING; ESCHERICHIA COLI; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; VALIDATION PROCESS;

AMINO ACID SEQUENCE; AMINO ACYL-TRNA SYNTHETASES; ANIMALS; BACTERIAL INFECTIONS; BACTERIOPHAGES; DISEASE MODELS, ANIMAL; DRUG DESIGN; ESCHERICHIA COLI; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE TRANSFER TECHNIQUES; GLUTATHIONE TRANSFERASE; MICE; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; PEPTIDE LIBRARY; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; SURVIVAL RATE; TETRACYCLINES;

ANIMALIA; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 12944335304     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.97.2.783     Document Type: Article

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