Effect of bosentan on nf-κb, inflammation, and tissue factor in angiotensin II-induced end-organ damage

Hypertension

Volumn 36, Issue 2, 2000, Pages 282-290

  Muller, Dominik N ^a   Mervaala, Eero M A ^a,b   Schmidt, Folke ^a   Park, Joon Keun ^a   Dechend, Ralf ^a   Genersch, Elke ^a   Breu, Volker ^e   Löffler, Bernd Michael ^e   Ganten, Detlev ^c   Schneider, Wolfgang ^a   Haller, Hermann ^d   Luft, Friedrich C ^a,f  

^a HUMBOLDT UNIVERSITY   (Germany)

^b UNIVERSITY OF HELSINKI   (Finland)

^c MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^d HANNOVER MEDICAL SCHOOL   (Germany)

^e F HOFFMANN LA ROCHE LTD   (Switzerland)

^f FRANZ VOLHARD CLINIC   (Germany)

Author keywords

Albuminuria; Angiotensin I; Endothelin; Genes; Renin angiotensin system

Indexed keywords

ALBUMIN; ANGIOTENSIN; BOSENTAN; HYDRALAZINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; THROMBOPLASTIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD CLOTTING; BLOOD PRESSURE REGULATION; CELL INFILTRATION; CONTROLLED STUDY; DRUG EFFECT; HEART INJURY; HEART MUSCLE NECROSIS; HEART VENTRICLE HYPERTROPHY; HYPERTENSION; INFLAMMATION; KIDNEY INJURY; KIDNEY NECROSIS; MACROPHAGE; MALE; MORTALITY; NONHUMAN; PRIORITY JOURNAL; PROTEINURIA; RAT; RECEPTOR BLOCKING; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

EID: 0033874297     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.36.2.282     Document Type: Article

References (43)

1. Adhesion molecule interactions in human glomerulonephritis: Importance of the tubulointerstitium
2. Experimental studies on the role of intercellular adhesion molecule-1 and lymphocyte function-associated antigen-1 in hypertensive nephrosclerosis
3. Integrins, adhesion, and cardiac remodeling
4. The cardiac renin-angiotensin system: An appraisal of present experimental and clinical evidence
5. Angiotensin II induces fibronectin expression associated with cardiac fibrosis in the rat
6. Angiotensin type 1 receptors mediate smooth muscle proliferation and endothelin biosynthesis in rat vascular smooth muscle
7. Induction of endothelin-1 gene by angiotensin and vasopressin in endothelial cells
8. Endothelin-1 expression in hearts of transgenic hypertensive mice
9. Endothelin: Potential role in hypertension and vascular hypertrophy
10. Angiotensin II increases tissue endothelin and induces vascular hypertrophy: Reversal by ET(A)-receptor antagonist
11. Role of endothelin-1 in hypertension
12. Inhibition of nuclear factor-κB-mediated adhesion molecule expression in human endothelial cells
13. Angiotensin II participates in mononuclear cell recruitment in experimental immune complex nephritis through nuclear factor-kB activation and monocyte chemoattractant protein-1 synthesis
14. The structural biology of expression and function of tissue factor
15. Tissue factor expression in an animal model of hydronephrosis
16. Expression of tissue factor in renal ischemic-reperfusion injury of the rat
17. Tissue factor is rapidly induced in arterial smooth muscle after balloon injury
18. Blood-borne tissue factor: Another view of thrombosis
19. Some thoughts about localization and expression of tissue factor
20. High human renin hypertension in transgenic rats
21. Hypertension-induced end-organ damage: A new transgenic approach to an old problem
22. Monocyte infiltration and adhesion molecules in a rat model of high human renin hypertension
23. Enhanced angiotensin II stimulates renal disorders in transgenic Tsukuba hypertensive mice
24. NF-κB inhibition ameliorates angiotensin II-induced inflammatory damage in rats
25. Radioimmunological determination of endothelin peptides in human plasma: A methodological approach
26. Blood pressure-independent organ damage in rats with human renin and angiotensinogen
27. Contribution of extracellular signal-regulated kinase to angiotensin II-induced transforming growth factor-β1 expression in vascular smooth muscle cells
28. Inhibitory effects of antioxidants on neonatal rat cardiac myocyte hypertrophy induced by tumor necrosis factor-α and angiotensin II
29. Angiotensin II-induced transactivation of epidermal growth factor receptor regulates flbronectin and transforming growth factor-β synthesis via transcriptional and posttranscriptional mechanisms
30. Role of tissue factor in adhesion of mononuclear phagocytes to and trafficking through endothelium in vitro
31. Prevention of the cardiovascular and renal effects of angiotensin II by endothelin blockade
32. Effect of endothelin antagonism on blood pressure and vascular structure in renovascular hypertensive rats
33. Macrophages in renal injury
34. Cell-mediated immunity in glomerular disease
35. Tissue factor controls the balance of angiogenic and anti-angiogenic properties of tumor cells in mice
36. In vivo transfection of cis element 'decoy' against nuclear factor-kappaB binding site prevents myocardial infarction
37. Pathophysiology of progressive nephropathies
38. Antiproteinuric therapy while preventing the abnormal protein traffic in proximal tubule abrogates protein- and complement-dependent interstitial inflammation in experimental renal disease
39. In situ detection of tissue factor within the coronary intima in rat cardiac allograft vasculopathy
40. 2+ mobilization and protein kinase C activation
41. Linkage between inflammation and coagulation: An update on the molecular basis of the cross-talk
42. VLA-4 integrin cross-linking on human monocytic THP-1 cells induces tissue factor expression by a mechanism involving mitogen-activated protein kinase
43. Integrin regulation of an inflammatory effector gene: Direct induction of the tissue factor promoter by engagement of beta 1 or alpha 4 integrin chains