Monocyte infiltration and adhesion molecules in a rat model of high human renin hypertension

Hypertension

Volumn 33, Issue 1 II, 1999, Pages 389-395

  Mervaala, Eero M A ^c   Müller, Dominik N ^c   Park, Joon Keun ^a   Schmidt, Folke ^c   Löhn, Matthias ^a   Breu, Volker ^b   Dragun, Duska ^c   Ganten, Detlev ^a   Haller, Herman ^c   Luft, Friedrich C ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

^c NONE

Author keywords

Angiotensin II; Fibronectin; Intercellular adhesion molecule 1; Plasminogen activator inhibitor 1; Renin; Vascular cell adhesion molecule 1

Indexed keywords

CELL ADHESION MOLECULE; CILAZAPRIL; FIBRONECTIN; INTERCELLULAR ADHESION MOLECULE 1; PLASMINOGEN ACTIVATOR INHIBITOR 1; VALSARTAN; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIUM CELL; ENZYME INHIBITION; EXTRACELLULAR MATRIX; HYPERTENSION; LEUKOCYTE ADHERENCE; MONOCYTE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

EID: 0345059270     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.hyp.33.1.389     Document Type: Article

References (15)

1. Mai M, Geiger H, Hilgers KF, Veelken R, Mann JFE, Dämmrich J, Luft FC. Early interstitial changes in hypertension-induced renal injury. Hypertension. 1993;22:754-765.
2. Mai M, Hilgers KF, Geiger H. Experimental studies on the role of intercellular adhesion molecule-1 and lymphocyte function-associated antigen-1 in hypertensive nephrosclerosis. Hypertension. 1996;28:973-979.
3. Ingelfinger JR, Dzau VJ. Molecular biology of renal injury: emphasis of the role of the renin-angiotensin system. J Am Soc Nephrol. 1991;2: S9-S20.
4. Lindpaintner K, Ganten D. The cardiac renin-angiotensin system: an appraisal of present experimental and clinical evidence. Circ Res. 1991; 68:905-921.
5. Bech Laursen J, Rajagopalan S, Galis Z, Tarpey M, Freeman BA, Harrison DG. Role of superoxide in angiotensin Il-induced but not catecholamine-induced hypertension. Circulation. 1997;95:588-593.
6. Gräfe M, Auch-Schwelk W, Zakrzewicz A, Regitz-Zagrosek V, Bartsch P, Graf K, Loebe M, Gaehtgens P, Fleck E. Angiotensin II-induced leukocyte adhesion on human coronary endothelial cells in mediated by E-selectin. Circ Res. 1997;81:804-811.
7. Bohlender J, Fukamizu A, Lippoldt A, Nomura T, Dietz R, Ménard J, Murakami K, Luft FC, Ganten D. High human renin hypertension in transgenic rats. Hypertension. 1997;29:428-434.
8. Dehmel B, Mervaala E, Lippoldt A, Gross V, Bohlender J, Ganten D, Luft FC. Pressure-natriuresis and -diuresis in transgenic rats harboring both human renin and human angiotensinogen genes. J Am Soc Nephrol. In press.
9. Dragun D, Tullius SG, Park JK, Maasch C, Lukitsch I, Lippoldt A, Gross V, Luft FC, Haller H. ICAM-1 antisense oligodesoxynucleotides prevent reperfusion injury and enhance immediate graft function in renal transplantation. Kidney Int. 1998;54:590-602.
10. Johnson RJ, Alpers CE, Yoshimura A, Lombards D, Pritzl P, Floege J, Schwartz SM. Renal injury form angiotensin II-mediated hypertension. Hypertension. 1992;19:464-474.
11. McCarron RM, Wang L, Siren AL, Spatz M, Hallenbeck JM. Adhesion molecules on normotensive and hypertensive rat brain endothelial cells. Proc Soc Exp Biol Med. 1994;205:257-262.
12. McCarron RM, Wang L, Siren AL, Spatz M, Hallenbeck JM. Monocyte adhesion to cerebrovascular endothelial cells derived from hypertensive and normotensive rats. Am J Physiol. 1994;267:H2491-H2497.
13. Komatsu S, Panes J, Russell JM, Anderson DC, Muzykantov VR, Miyasaka M, Granger DN. Effects of chronic arterial hypertension on constitutive and induced intercellular adhesion molecule-1 expression in vivo. Hypertension. 1997;29:683-689.
14. Oikawa T, Freeman M, Lo W, Vaughan DE, Fogo A. Modulation of plasminogen activator inhibitor-1 in vivo: a new mechanism for the anti-fibrotic effect of renin-angiotensin inhibition. Kidney Int. 1997;51: 164-172.
15. Coassolo P, Fischli W, Clozel JP, Chou RC. Pharmacokinetics of remikiren, a potent orally active inhibitor of human renin, in rat, dog and primates. Xenobiotica. 1996;26:333-345.