Lack of endothelial nitric oxide synthase aggravates murine accelerated anti-glomerular basement membrane glomerulonephritis

American Journal of Pathology

Volumn 156, Issue 3, 2000, Pages 879-888

  Heeringa, Peter ^a   Van Goor, Harry ^b   Itoh Lindstrom, Yoshie ^a   Maeda, Nobuyo ^a   Falk, Ronald J ^a   Assmann, Karel J M ^c   Kallenberg, Cees G M ^b   Jennette, J Charles ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD VESSEL TONE; CONTROLLED STUDY; DISEASE EXACERBATION; ENDOTHELIUM; GENE CONTROL; GENE DISRUPTION; GLOMERULONEPHRITIS; GLOMERULUS BASEMENT MEMBRANE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; RENAL ARTERY THROMBOSIS;

EID: 0033871518     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)64957-7     Document Type: Article

References (24)

1. Genetic analysis of nitric oxide synthase isoforms: Targeted mutation in mice
2. Topography of nitric oxide synthesis by localizing constitutive NO synthases in mammalian kidney
3. Nitric oxide as antiinflammatory agent
4. Nitric oxide synthases: Which, where, how, and why?
5. Inducible nitric oxide synthase: What difference does it make?
6. Nitric oxide and glomerulonephritis
7. The nitric oxide pathway in glomerulonephritis
8. Role of nitric oxide in rat nephrotoxic nephritis: Comparison between inducible and constitutive nitric oxide synthase
9. Nitric oxide mediates immunologic injury to kidney mesangium in experimental glomerulonephritis
10. L-arginine depletion inhibits glomerular nitric oxide synthesis and exacerbates rat nephrotoxic nephritis
11. Exogenous nitric oxide prevents endotoxin-induced glomerular thrombosis in rats
12. Expression of iNOS, eNOS, and peroxynitrite-modified proteins in experimental anti-myeloperoxidase associated crescentic glomerulonephritis
13. Anti-GBM glomerulonephritis in mice lacking nitric oxide synthase type 2
14. Elevated blood pressures in mice lacking endothelial nitric oxide synthase
15. Anti-GBM nephritis in the mouse: Severe proteinuria in the heterologous phase
16. Peroxynitrite: Reactive, invasive and enigmatic
17. Consequences of acute nitric oxide synthesis inhibition in experimental glomerulonephritis
18. Hypertension in mice lacking the gene for endothelial nitric oxide synthase
19. Chronic blockade of nitric oxide synthesis in the rat produces systemic hypertension and glomerular damage
20. Losartan-sensitive renal damage caused by chronic NOS inhibition does not involve increased renal angiotensin II concentrations
21. Aggravation of experimental glomerulonephritis by superimposed clip nypertension
22. Differential effects of nonselective nitric oxide synthase (NOS) and selective inducible NOS inhibition on hepatic necrosis, apoptosis, ICAM-1 expression, and neutrophil accumulation during endotoxemia
23. NO modulates P-selectin and ICAM-1 mRNA expression and hemodynamic alterations in hepatic I/R
24. Chronic blockade of NO synthase activity induces a proinflammatory phenotype in the arterial wall: Prevention by angiotensin II antagonism