DNA vaccines

Japanese Journal of Pharmacology

Volumn 83, Issue 3, 2000, Pages 167-174

  Koide, Y ^a   Nagata, T ^a   Yoshida, A ^a   Uchijima, M ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

CpG motif; Cytotoxic T lymphocyte; DNA vaccine; Plasmid

Indexed keywords

BACTERIAL PROTEIN; DNA VACCINE; GAMMA INTERFERON; GLYCOPROTEIN GP 160; HEPATITIS B SURFACE ANTIGEN; INTERLEUKIN 12; PLASMID DNA; PROTOZOAL PROTEIN; REACTIVE OXYGEN METABOLITE; VIRUS NUCLEOPROTEIN;

B CELL LYMPHOMA; BACTERIAL INFECTION; CLINICAL TRIAL; CYTOTOXIC T LYMPHOCYTE; DRUG DELIVERY SYSTEM; ESCHERICHIA COLI; GENE GUN; HEPATITIS B VIRUS; HISTOCOMPATIBILITY COMPLEX; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE RESPONSE; IMMUNIZATION; INFLUENZA VIRUS A; LEUKOCYTE ACTIVATION; LISTERIA MONOCYTOGENES; MALARIA FALCIPARUM; MELANOMA; NONHUMAN; REVIEW; TUBERCULOSIS; VIRUS INFECTION;

ANIMALS; CLINICAL TRIALS; MODELS, ANIMAL; PLASMIDS; VACCINES, DNA;

EID: 0033868659     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.83.167     Document Type: Review

References (32)

1. DNA-mediated immunization in mice induces a potent MHC class I-restricted cytotoxic T lymphocyte response to the hepatitis B envelope protein
2. Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization
3. Cancer therapy using a self-replicating RNA vaccine
4. DNA-based immunization induces continuous secretion of hepatitis B surface antigen and high levels of circulating antibody
5. Pharmacological enhancement of in vivo foreign gene expression in muscle
6. Influenza virus nucleoprotein specific immunoglobulin G subclass and cytokine responses elicited by DNA vaccination are dependent on the route of vector DNA delivery
7. Gene vaccination with naked plasmid DNA: Mechanism of CTL priming
8. DNA vaccines
9. Differential dependence on target site tissue for gene gun and intramuscular DNA immunizations
10. Different T helper cell types and antibody isotypes generated by saline and gene gun DNA immunization
11. CpG motifs in bacterial DNA trigger direct B cell activation
12. CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma
13. CpG motifs in bacterial DNA activate leukocytes through the pH- dependent generation of reactive oxygen species
14. Advantage of gene gun-mediated over intramuscular inoculation of plasmid DNA vaccine in reproducible induction of specific immune responses
15. Protective immunity by intramuscular injection of low doses of influenza virus DNA vaccines
16. Enhancement of cell-mediated immunity against HIV-1 induced by coinnoculation of plasmid-encoded HIV-1 antigen with plasmid expressing IL-12
17. DNA vaccines for infections with intracellular bacteria
18. Optimization of codon usage of plasmid DNA vaccine is required for the effective MHC class I restricted T cell responses against an intracellular bacterium
19. Codon optimization effect on translational efficiency of DNA vaccine in mammalian cells: Analysis of plasmid DNA encoding a CTL epitope derived from microorganisms
20. Vaccination against tuberculosis by DNA injection
21. Immunogenicity and protective efficacy of a tuberculosis DNA vaccine
22. Immunogenicity and efficacy of a tuberculosis DNA vaccine encoding the components of the secreted antigen 85 complex
23. Induction of humoral and cellular immune responses by vaccination with M. tuberculosis antigen 85 DNA
24. Therapy of tuberculosis in mice by DNA vaccination
25. Induction of antigen-specific tumor immunity by genetic and cellular vaccines against MAGE: Enhanced tumor protection by coexpression of granulocyte-macrophage colony-stimulating factor and B7-1
26. Injection of complementary DNA encoding interleukin-12 inhibits tumor establishment at a distant site in a murine renal carcinoma model
27. Gene gun-mediated skin transfection with interleukin 12 gene results in regression of established primary and metastatic murine tumors
28. DNA vaccination with HIV-1 expressing constructs elicits immune responses in humans
29. Phase 1 safety and immune response studies of a DNA vaccine encoding hepatitis B surface antigen delivered by a gene delivery device
30. The development of malaria vaccines: SPf66- what next?
31. Colorectal cancer vaccines
32. Phase I/IB study of immunization with autologous tumor cells transfected with the GM-CSF gene by particle mediated transfer in patients with melanoma or sarcoma