메뉴 건너뛰기




Volumn 10, Issue 4, 2000, Pages 498-503

Olfaction in Drosophila

Author keywords

[No Author keywords available]

Indexed keywords

DROSOPHILA; GENOME; MOLECULAR GENETICS; MULTIGENE FAMILY; NONHUMAN; OLFACTORY DISCRIMINATION; OLFACTORY RECEPTOR; OLFACTORY SYSTEM; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

EID: 0033867716     PISSN: 09594388     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-4388(00)00111-2     Document Type: Review
Times cited : (121)

References (65)
  • 1
    • 0028967278 scopus 로고
    • Analysis of chemical signals by nervous systems
    • Hildebrand J.G. Analysis of chemical signals by nervous systems. Proc Natl Acad Sci USA. 92:1995;67-74.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 67-74
    • Hildebrand, J.G.1
  • 4
    • 0025825726 scopus 로고
    • A novel multigene family may encode odorant receptors: A molecular basis for odor recognition
    • Buck L., Axel R. A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. Cell. 65:1991;175-187.
    • (1991) Cell , vol.65 , pp. 175-187
    • Buck, L.1    Axel, R.2
  • 7
    • 0344200118 scopus 로고    scopus 로고
    • Identification of candidate Drosophila olfactory receptors from genomic DNA sequence
    • Gao Q., Chess A. Identification of candidate Drosophila olfactory receptors from genomic DNA sequence. Genomics. 60:1999;31-39.
    • (1999) Genomics , vol.60 , pp. 31-39
    • Gao, Q.1    Chess, A.2
  • 8
    • 0032509484 scopus 로고    scopus 로고
    • Neurobiology of the Caenorhabditis elegans genome
    • Bargmann C.I. Neurobiology of the Caenorhabditis elegans genome. Science. 282:1998;2028-2033.
    • (1998) Science , vol.282 , pp. 2028-2033
    • Bargmann, C.I.1
  • 9
    • 0033595696 scopus 로고    scopus 로고
    • Seven-transmembrane proteins as odorant and chemosensory receptors
    • Mombaerts P. Seven-transmembrane proteins as odorant and chemosensory receptors. Science. 286:1999;707-711.
    • (1999) Science , vol.286 , pp. 707-711
    • Mombaerts, P.1
  • 10
    • 0029887597 scopus 로고    scopus 로고
    • Odr-10 encodes a seven transmembrane domain olfactory receptor required for responses to the odorant diacetyl
    • Sengupta P., Chou J.H., Bargmann C.I. odr-10 encodes a seven transmembrane domain olfactory receptor required for responses to the odorant diacetyl. Cell. 84:1996;899-909.
    • (1996) Cell , vol.84 , pp. 899-909
    • Sengupta, P.1    Chou, J.H.2    Bargmann, C.I.3
  • 13
    • 0030717502 scopus 로고    scopus 로고
    • The Caenorhabditis elegans seven-transmembrane protein ODR-10 functions as an odorant receptor in mammalian cells
    • Zhang Y., Chou J.H., Bradley J., Bargmann C.I., Zinn K. The Caenorhabditis elegans seven-transmembrane protein ODR-10 functions as an odorant receptor in mammalian cells. Proc Natl Acad Sci USA. 94:1997;12162-12167.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 12162-12167
    • Zhang, Y.1    Chou, J.H.2    Bradley, J.3    Bargmann, C.I.4    Zinn, K.5
  • 14
    • 0032417641 scopus 로고    scopus 로고
    • Identification of ligands for olfactory receptors by functional expression of a receptor library
    • Krautwurst D., Yau K.W., Reed R.R. Identification of ligands for olfactory receptors by functional expression of a receptor library. Cell. 95:1998;917-926.
    • (1998) Cell , vol.95 , pp. 917-926
    • Krautwurst, D.1    Yau, K.W.2    Reed, R.R.3
  • 15
    • 0033525727 scopus 로고    scopus 로고
    • Combinatorial receptor codes for odors
    • A technical tour-de-force that follows calcium imaging of dissociated olfactory neurons with single-cell PCR to isolate the neuron's OR. Not only do the results provide formal proof of the theory that a given ORN expresses only a single OR, but they also allow the association of an OR sequence with the odorants that interact functionally with that receptor. Multiple odorants are found to activate a single OR, and a given odorant activates multiple ORs.
    • Malnic B., Hirono J., Sato T., Buck L.B. Combinatorial receptor codes for odors. Cell. 96:1999;713-723. A technical tour-de-force that follows calcium imaging of dissociated olfactory neurons with single-cell PCR to isolate the neuron's OR. Not only do the results provide formal proof of the theory that a given ORN expresses only a single OR, but they also allow the association of an OR sequence with the odorants that interact functionally with that receptor. Multiple odorants are found to activate a single OR, and a given odorant activates multiple ORs.
    • (1999) Cell , vol.96 , pp. 713-723
    • Malnic, B.1    Hirono, J.2    Sato, T.3    Buck, L.B.4
  • 17
    • 0028084578 scopus 로고
    • The organization of the chemosensory system in Drosophila melanogaster: A review
    • Stocker R.F. The organization of the chemosensory system in Drosophila melanogaster: a review. Cell Tissue Res. 275:1994;3-26.
    • (1994) Cell Tissue Res , vol.275 , pp. 3-26
    • Stocker, R.F.1
  • 18
    • 0034629479 scopus 로고    scopus 로고
    • Candidate taste receptors in Drosophila
    • Clyne P.J., Warr C.G., Carlson J.R. Candidate taste receptors in Drosophila. Science. 287:2000;1830-1834.
    • (2000) Science , vol.287 , pp. 1830-1834
    • Clyne, P.J.1    Warr, C.G.2    Carlson, J.R.3
  • 19
    • 0342506464 scopus 로고    scopus 로고
    • Coexpression of two odorant-binding protein homologs in Drosophila: Implications for olfactory coding
    • Hekmat-Scafe D.S., Steinbrecht R.A., Carlson J.R. Coexpression of two odorant-binding protein homologs in Drosophila: implications for olfactory coding. J Neurosci. 17:1997;1616-1624.
    • (1997) J Neurosci , vol.17 , pp. 1616-1624
    • Hekmat-Scafe, D.S.1    Steinbrecht, R.A.2    Carlson, J.R.3
  • 20
    • 0034076880 scopus 로고    scopus 로고
    • Expression patterns of two putative odorant-binding proteins in the olfactory organs of Drosophila have different implications for their functions
    • Park S-K., Shanbhag S.R., Wang Q., Hasan G., Steinbrecht R.A., Pikielny C.W. Expression patterns of two putative odorant-binding proteins in the olfactory organs of Drosophila have different implications for their functions. Cell Tissue Res. 300:2000;181-192.
    • (2000) Cell Tissue Res , vol.300 , pp. 181-192
    • Park, S.-K.1    Shanbhag, S.R.2    Wang, Q.3    Hasan, G.4    Steinbrecht, R.A.5    Pikielny, C.W.6
  • 21
    • 0031691884 scopus 로고    scopus 로고
    • LUSH odorant-binding protein mediates chemosensory responses to alcohols in Drosophila melanogaster
    • Kim M.S., Repp A., Smith D.P. LUSH odorant-binding protein mediates chemosensory responses to alcohols in Drosophila melanogaster. Genetics. 150:1998;711-721.
    • (1998) Genetics , vol.150 , pp. 711-721
    • Kim, M.S.1    Repp, A.2    Smith, D.P.3
  • 22
    • 0028178393 scopus 로고
    • Putative Drosophila pheromone-binding proteins expressed in a subregion of the olfactory system
    • McKenna M.P., Hekmat-Scafe D.S., Gaines P., Carlson J.R. Putative Drosophila pheromone-binding proteins expressed in a subregion of the olfactory system. J Biol Chem. 269:1994;16340-16347.
    • (1994) J Biol Chem , vol.269 , pp. 16340-16347
    • McKenna, M.P.1    Hekmat-Scafe, D.S.2    Gaines, P.3    Carlson, J.R.4
  • 23
    • 0028123735 scopus 로고
    • Members of a family of Drosophila putative odorant-binding proteins are expressed in different subsets of olfactory hairs
    • Pikielny C.W., Hasan G., Rouyer F., Rosbash M. Members of a family of Drosophila putative odorant-binding proteins are expressed in different subsets of olfactory hairs. Neuron. 12:1994;35-49.
    • (1994) Neuron , vol.12 , pp. 35-49
    • Pikielny, C.W.1    Hasan, G.2    Rouyer, F.3    Rosbash, M.4
  • 24
    • 0033230041 scopus 로고    scopus 로고
    • Diversity of odourant binding proteins revealed by an expressed sequence tag project on male Manduca Sexta moth antennae
    • Robertson H.M., Martos R., Sears C.R., Todres E.Z., Walden K.K., Nardi J.B. Diversity of odourant binding proteins revealed by an expressed sequence tag project on male Manduca Sexta moth antennae. Insect Mol Biol. 8:1999;501-518.
    • (1999) Insect Mol Biol , vol.8 , pp. 501-518
    • Robertson, H.M.1    Martos, R.2    Sears, C.R.3    Todres, E.Z.4    Walden, K.K.5    Nardi, J.B.6
  • 25
    • 0032820561 scopus 로고    scopus 로고
    • Odorant binding protein diversity and distribution among the insect orders, as indicated by LAP, an OBP-related protein of the true bug Lygus lineolaris (Hemiptera, Heteroptera)
    • Vogt R.G., Callahan F.E., Rogers M.E., Dickens J.C. Odorant binding protein diversity and distribution among the insect orders, as indicated by LAP, an OBP-related protein of the true bug Lygus lineolaris (Hemiptera, Heteroptera). Chem Senses. 24:1999;481-495.
    • (1999) Chem Senses , vol.24 , pp. 481-495
    • Vogt, R.G.1    Callahan, F.E.2    Rogers, M.E.3    Dickens, J.C.4
  • 26
    • 0034013791 scopus 로고    scopus 로고
    • Molecular evolution of odorant-binding protein genes OS-E and OS-F in Drosophila
    • Hekmat-Scafe D.S., Dorit R.L., Carlson J.R. Molecular evolution of odorant-binding protein genes OS-E and OS-F in Drosophila. Genetics. 155:2000;117-127.
    • (2000) Genetics , vol.155 , pp. 117-127
    • Hekmat-Scafe, D.S.1    Dorit, R.L.2    Carlson, J.R.3
  • 27
    • 0028373298 scopus 로고
    • Towards a common strategy for transducing olfactory information
    • Ache B.W. Towards a common strategy for transducing olfactory information. Semin Cell Biol. 5:1994;55-63.
    • (1994) Semin Cell Biol , vol.5 , pp. 55-63
    • Ache, B.W.1
  • 28
    • 0031043834 scopus 로고    scopus 로고
    • Mechanisms of olfactory discrimination: Converging evidence for common principles across phyla
    • Hildebrand J.G., Shepherd G.M. Mechanisms of olfactory discrimination: converging evidence for common principles across phyla. Annu Rev Neurosci. 20:1997;595-631.
    • (1997) Annu Rev Neurosci , vol.20 , pp. 595-631
    • Hildebrand, J.G.1    Shepherd, G.M.2
  • 29
  • 30
    • 0030273253 scopus 로고    scopus 로고
    • General anosmia caused by a targeted disruption of the mouse olfactory cyclic nucleotide-gated cation channel
    • Brunet L.J., Gold G.H., Ngai J. General anosmia caused by a targeted disruption of the mouse olfactory cyclic nucleotide-gated cation channel. Neuron. 17:1996;681-693.
    • (1996) Neuron , vol.17 , pp. 681-693
    • Brunet, L.J.1    Gold, G.H.2    Ngai, J.3
  • 31
    • 0032904017 scopus 로고    scopus 로고
    • The complete family of genes encoding G proteins of Caenorhabditis elegans
    • In an impressive example of the power of genomics, these authors have scanned the completed C. elegans genome and assembled a complete list of all G proteins. They proceed to analyze the expression of 13 of these using reporter-fusion constructs, and find that many are expressed in sensory neurons. Mutations of four Gα subunits produce chemosensory defects, extending the work described in [32].
    • Jansen G., Thijssen K.L., Werner P., van der Horst M., Hazendonk E., Plasterk R.H. The complete family of genes encoding G proteins of Caenorhabditis elegans. Nat Genet. 21:1999;414-419. In an impressive example of the power of genomics, these authors have scanned the completed C. elegans genome and assembled a complete list of all G proteins. They proceed to analyze the expression of 13 of these using reporter-fusion constructs, and find that many are expressed in sensory neurons. Mutations of four Gα subunits produce chemosensory defects, extending the work described in [32].
    • (1999) Nat Genet , vol.21 , pp. 414-419
    • Jansen, G.1    Thijssen, K.L.2    Werner, P.3    Van Der Horst, M.4    Hazendonk, E.5    Plasterk, R.H.6
  • 32
    • 0031934849 scopus 로고    scopus 로고
    • The G alpha protein ODR-3 mediates olfactory and nociceptive function and controls cilium morphogenesis in C. elegans olfactory neurons
    • Roayaie K., Crump J.G., Sagasti A., Bargmann C.I. The G alpha protein ODR-3 mediates olfactory and nociceptive function and controls cilium morphogenesis in C. elegans olfactory neurons. Neuron. 20:1998;55-67.
    • (1998) Neuron , vol.20 , pp. 55-67
    • Roayaie, K.1    Crump, J.G.2    Sagasti, A.3    Bargmann, C.I.4
  • 33
    • 0030273625 scopus 로고    scopus 로고
    • A putative cyclic nucleotide-gated channel is required for sensory development and function in C. elegans
    • Coburn C.M., Bargmann C.I. A putative cyclic nucleotide-gated channel is required for sensory development and function in C. elegans. Neuron. 17:1996;695-706.
    • (1996) Neuron , vol.17 , pp. 695-706
    • Coburn, C.M.1    Bargmann, C.I.2
  • 34
    • 0030273005 scopus 로고    scopus 로고
    • Mutations in a cyclic nucleotide-gated channel lead to abnormal thermosensation and chemosensation in C. elegans
    • Komatsu H., Mori I., Rhee J.S., Akaike N., Ohshima Y. Mutations in a cyclic nucleotide-gated channel lead to abnormal thermosensation and chemosensation in C. elegans. Neuron. 17:1996;707-718.
    • (1996) Neuron , vol.17 , pp. 707-718
    • Komatsu, H.1    Mori, I.2    Rhee, J.S.3    Akaike, N.4    Ohshima, Y.5
  • 35
    • 0030776196 scopus 로고    scopus 로고
    • OSM-9, a novel protein with structural similarity to channels, is required for olfaction, mechanosensation, and olfactory adaptation in Caenorhabditis elegans
    • Colbert H.A., Smith T.L., Bargmann C.I. OSM-9, a novel protein with structural similarity to channels, is required for olfaction, mechanosensation, and olfactory adaptation in Caenorhabditis elegans. J Neurosci. 17:1997;8259-8269.
    • (1997) J Neurosci , vol.17 , pp. 8259-8269
    • Colbert, H.A.1    Smith, T.L.2    Bargmann, C.I.3
  • 36
    • 0032146259 scopus 로고    scopus 로고
    • + channel gene ether a go-go is required for the transduction of a subset of odorants in adult Drosophila melanogaster
    • + channel gene ether a go-go is required for the transduction of a subset of odorants in adult Drosophila melanogaster. J Neurosci. 18:1998;5603-5613.
    • (1998) J Neurosci , vol.18 , pp. 5603-5613
    • Dubin, A.E.1    Liles, M.M.2    Harris, G.L.3
  • 37
    • 0027994863 scopus 로고
    • Primary structure and functional expression of a Drosophila cyclic nucleotide-gated channel present in eyes and antennae
    • Baumann A., Frings S., Godde M., Seifert R., Kaupp U.B. Primary structure and functional expression of a Drosophila cyclic nucleotide-gated channel present in eyes and antennae. EMBO J. 13:1994;5040-5050.
    • (1994) EMBO J , vol.13 , pp. 5040-5050
    • Baumann, A.1    Frings, S.2    Godde, M.3    Seifert, R.4    Kaupp, U.B.5
  • 38
    • 0029584040 scopus 로고
    • Identification of a Drosophila G protein alpha subunit (dGq alpha-3) expressed in chemosensory cells and central neurons
    • Talluri S., Bhatt A., Smith D.P. Identification of a Drosophila G protein alpha subunit (dGq alpha-3) expressed in chemosensory cells and central neurons. Proc Natl Acad Sci USA. 92:1995;11475-11479.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 11475-11479
    • Talluri, S.1    Bhatt, A.2    Smith, D.P.3
  • 40
    • 0033385877 scopus 로고    scopus 로고
    • Molecular cloning of a putative voltage- And cyclic nucleotide-gated ion channel present in the antennae and eyes of Drosophila melanogaster
    • Marx T., Gisselmann G., Störtkuhl K.F., Hovemann B.T., Hatt H. Molecular cloning of a putative voltage- and cyclic nucleotide-gated ion channel present in the antennae and eyes of Drosophila melanogaster. Invert Neurosci. 4:1999;55-63.
    • (1999) Invert Neurosci , vol.4 , pp. 55-63
    • Marx, T.1    Gisselmann, G.2    Störtkuhl, K.F.3    Hovemann, B.T.4    Hatt, H.5
  • 41
    • 0028987239 scopus 로고
    • Requirement for a phospholipase C in odor response: Overlap between olfaction and vision in Drosophila
    • Riesgo-Escovar J., Raha D., Carlson J.R. Requirement for a phospholipase C in odor response: overlap between olfaction and vision in Drosophila. Proc Natl Acad Sci USA. 92:1995;2864-2868.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 2864-2868
    • Riesgo-Escovar, J.1    Raha, D.2    Carlson, J.R.3
  • 42
    • 0028639915 scopus 로고
    • Olfactory physiology in the Drosophila maxillary palp requires the visual system gene rdgB
    • Riesgo-Escovar J.R., Woodard C., Carlson J.R. Olfactory physiology in the Drosophila maxillary palp requires the visual system gene rdgB. J Comp Physiol [A]. 175:1994;687-693.
    • (1994) J Comp Physiol [A] , vol.175 , pp. 687-693
    • Riesgo-Escovar, J.R.1    Woodard, C.2    Carlson, J.R.3
  • 43
    • 0034608476 scopus 로고    scopus 로고
    • The inositol 1,4,5-trisphosphate receptor is required for maintenance of olfactory adaptation in Drosophila antennae
    • Deshpande M., Venkatesh K., Rodrigues V., Hasan G. The inositol 1,4,5-trisphosphate receptor is required for maintenance of olfactory adaptation in Drosophila antennae. J Neurobiol. 43:2000;282-288.
    • (2000) J Neurobiol , vol.43 , pp. 282-288
    • Deshpande, M.1    Venkatesh, K.2    Rodrigues, V.3    Hasan, G.4
  • 44
    • 0031014411 scopus 로고    scopus 로고
    • Voltage-activated and odor-modulated conductances in olfactory neurons of Drosophila melanogaster
    • Dubin A.E., Harris G.L. Voltage-activated and odor-modulated conductances in olfactory neurons of Drosophila melanogaster. J Neurobiol. 32:1997;123-137.
    • (1997) J Neurobiol , vol.32 , pp. 123-137
    • Dubin, A.E.1    Harris, G.L.2
  • 45
    • 0001715938 scopus 로고
    • Neurogenetics of olfaction in Drosophila melanogaster
    • Siddiqi O. Neurogenetics of olfaction in Drosophila melanogaster. Trends Genet. 3:1987;137-142.
    • (1987) Trends Genet , vol.3 , pp. 137-142
    • Siddiqi, O.1
  • 46
    • 0033083762 scopus 로고    scopus 로고
    • The odor specificities of a subset of olfactory receptor neurons are governed by Acj6, a POU-domain transcription factor
    • The authors describe the molecular characterization of the acj6 Drosophila mutant, first isolated because of its abnormal response in an assay that couples odorant application to a stereotyped startle response. acj6 is mapped to a previously described gene called I-POU, which encodes a POU-type homeodomain protein. Although the Acj6 protein is expressed in all ORNs, it is required for the expression of only a subset of DOR genes.
    • Clyne P.J., Certel S.J., de Bruyne M., Zaslavsky L., Johnson W.A., Carlson J.R. The odor specificities of a subset of olfactory receptor neurons are governed by Acj6, a POU-domain transcription factor. Neuron. 22:1999;339-347. The authors describe the molecular characterization of the acj6 Drosophila mutant, first isolated because of its abnormal response in an assay that couples odorant application to a stereotyped startle response. acj6 is mapped to a previously described gene called I-POU, which encodes a POU-type homeodomain protein. Although the Acj6 protein is expressed in all ORNs, it is required for the expression of only a subset of DOR genes.
    • (1999) Neuron , vol.22 , pp. 339-347
    • Clyne, P.J.1    Certel, S.J.2    De Bruyne, M.3    Zaslavsky, L.4    Johnson, W.A.5    Carlson, J.R.6
  • 47
    • 0031389727 scopus 로고    scopus 로고
    • Odorant response of individual sensilla on the Drosophila antenna
    • Clyne P., Grant A., O'Connell R., Carlson J.R. Odorant response of individual sensilla on the Drosophila antenna. Invert Neurosci. 3:1997;127-135.
    • (1997) Invert Neurosci , vol.3 , pp. 127-135
    • Clyne, P.1    Grant, A.2    O'Connell, R.3    Carlson, J.R.4
  • 48
    • 0033152269 scopus 로고    scopus 로고
    • Odor coding in a model olfactory organ: The Drosophila maxillary palp
    • This paper uses single-unit extracellular recordings of single maxillary palp sensilla to define a total of six functional types of neuron in this olfactory organ. A diversity of electrophysiological responses is encountered that includes excitatory and inhibitory responses, with slow or fast recovery profiles, depending on the odorant applied.
    • de Bruyne M., Clyne P.J., Carlson J.R. Odor coding in a model olfactory organ: the Drosophila maxillary palp. J Neurosci. 19:1999;4520-4532. This paper uses single-unit extracellular recordings of single maxillary palp sensilla to define a total of six functional types of neuron in this olfactory organ. A diversity of electrophysiological responses is encountered that includes excitatory and inhibitory responses, with slow or fast recovery profiles, depending on the odorant applied.
    • (1999) J Neurosci , vol.19 , pp. 4520-4532
    • De Bruyne, M.1    Clyne, P.J.2    Carlson, J.R.3
  • 49
    • 0028825369 scopus 로고
    • Divergent seven transmembrane receptors are candidate chemosensory receptors in C. elegans
    • Troemel E.R., Chou J.H., Dwyer N.D., Colbert H.A., Bargmann C.I. Divergent seven transmembrane receptors are candidate chemosensory receptors in C. elegans. Cell. 83:1995;207-218.
    • (1995) Cell , vol.83 , pp. 207-218
    • Troemel, E.R.1    Chou, J.H.2    Dwyer, N.D.3    Colbert, H.A.4    Bargmann, C.I.5
  • 50
    • 0030669834 scopus 로고    scopus 로고
    • Reprogramming chemotaxis responses: Sensory neurons define olfactory preferences in C. elegans
    • Troemel E.R., Kimmel B.E., Bargmann C.I. Reprogramming chemotaxis responses: sensory neurons define olfactory preferences in C. elegans. Cell. 91:1997;161-169.
    • (1997) Cell , vol.91 , pp. 161-169
    • Troemel, E.R.1    Kimmel, B.E.2    Bargmann, C.I.3
  • 51
    • 0028953087 scopus 로고
    • Cellular events during development of the olfactory sense organs in Drosophila melanogaster
    • Ray K., Rodrigues V. Cellular events during development of the olfactory sense organs in Drosophila melanogaster. Dev Biol. 167:1995;426-438.
    • (1995) Dev Biol , vol.167 , pp. 426-438
    • Ray, K.1    Rodrigues, V.2
  • 52
    • 0031049214 scopus 로고    scopus 로고
    • Development of the Drosophila olfactory sense organs utilizes cell-cell interactions as well as lineage
    • Reddy G.V., Gupta B., Ray K., Rodrigues V. Development of the Drosophila olfactory sense organs utilizes cell-cell interactions as well as lineage. Development. 124:1997;703-712.
    • (1997) Development , vol.124 , pp. 703-712
    • Reddy, G.V.1    Gupta, B.2    Ray, K.3    Rodrigues, V.4
  • 53
    • 0031089581 scopus 로고    scopus 로고
    • Atonal is a proneural gene for a subset of olfactory sense organs in Drosophila
    • Gupta B.P., Rodrigues V. Atonal is a proneural gene for a subset of olfactory sense organs in Drosophila. Genes Cells. 2:1997;225-233.
    • (1997) Genes Cells , vol.2 , pp. 225-233
    • Gupta, B.P.1    Rodrigues, V.2
  • 55
    • 0034026869 scopus 로고    scopus 로고
    • The proneural gene amos promotes multiple dendritic neuron formation in the Drosophila peripheral nervous system
    • •] describe a novel bHLH protein related to atonal that probably participates in patterning the olfactory sensory organs. Although an amos mutant is not available, misexpression studies demonstrate that amos has neurogenic activity in both the embryonic peripheral nervous system and adult olfactory organs.
    • •] describe a novel bHLH protein related to atonal that probably participates in patterning the olfactory sensory organs. Although an amos mutant is not available, misexpression studies demonstrate that amos has neurogenic activity in both the embryonic peripheral nervous system and adult olfactory organs.
    • (2000) Neuron , vol.25 , pp. 57-67
    • Huang, M.-L.1    Hsu, C.-H.2    Chien, C.-T.3
  • 56
    • 0032533675 scopus 로고    scopus 로고
    • Patterning an epidermal field: Drosophila lozenge, a member of the AML-1/Runt family of transcription factors, specifies olfactory sense organ type in a dose-dependent manner
    • Gupta B.P., Flores G.V., Banerjee U., Rodrigues V. Patterning an epidermal field: Drosophila lozenge, a member of the AML-1/Runt family of transcription factors, specifies olfactory sense organ type in a dose-dependent manner. Dev Biol. 203:1998;400-411.
    • (1998) Dev Biol , vol.203 , pp. 400-411
    • Gupta, B.P.1    Flores, G.V.2    Banerjee, U.3    Rodrigues, V.4
  • 57
    • 0032478533 scopus 로고    scopus 로고
    • Odorant receptors govern the formation of a precise topographic map
    • Wang F., Nemes A., Mendelsohn M., Axel R. Odorant receptors govern the formation of a precise topographic map. Cell. 93:1998;47-60.
    • (1998) Cell , vol.93 , pp. 47-60
    • Wang, F.1    Nemes, A.2    Mendelsohn, M.3    Axel, R.4
  • 58
    • 0033594145 scopus 로고    scopus 로고
    • Three-dimensional reconstruction of the antennal lobe in Drosophila melanogaster
    • The authors of this paper present a beautiful atlas of the antennal lobe in three dimensions that catalogues a total of 43 glomeruli. Laissue et al. use a new monoclonal antibody, nc82, to permit the visualization of all central neuropil in the fly brain and apply sophisticated software to render confocal microscope image-stacks into three-dimensional models.
    • Laissue P.P., Reiter C., Hiesinger P.R., Halter S., Fischbach K.F., Stocker R.F. Three-dimensional reconstruction of the antennal lobe in Drosophila melanogaster. J Comp Neurol. 405:1999;543-552. The authors of this paper present a beautiful atlas of the antennal lobe in three dimensions that catalogues a total of 43 glomeruli. Laissue et al. use a new monoclonal antibody, nc82, to permit the visualization of all central neuropil in the fly brain and apply sophisticated software to render confocal microscope image-stacks into three-dimensional models.
    • (1999) J Comp Neurol , vol.405 , pp. 543-552
    • Laissue, P.P.1    Reiter, C.2    Hiesinger, P.R.3    Halter, S.4    Fischbach, K.F.5    Stocker, R.F.6
  • 59
    • 0033166536 scopus 로고    scopus 로고
    • Optical imaging of odorant representations in the mammalian olfactory bulb
    • This paper uses intrinsic signal imaging to visualize glomerular activation in response to a variety of odorants in the rat. Small numbers of bilaterally symmetric glomeruli are activated in response to a given odorant. As the concentration of applied odorant is increased, additional glomeruli are activated.
    • Rubin B.D., Katz L.C. Optical imaging of odorant representations in the mammalian olfactory bulb. Neuron. 23:1999;499-511. This paper uses intrinsic signal imaging to visualize glomerular activation in response to a variety of odorants in the rat. Small numbers of bilaterally symmetric glomeruli are activated in response to a given odorant. As the concentration of applied odorant is increased, additional glomeruli are activated.
    • (1999) Neuron , vol.23 , pp. 499-511
    • Rubin, B.D.1    Katz, L.C.2
  • 60
    • 1842328641 scopus 로고    scopus 로고
    • Representation of odours and odour mixtures visualized in the honeybee brain
    • Joerges J., Küttner A., Galizia C.G., Menzel R. Representation of odours and odour mixtures visualized in the honeybee brain. Nature. 387:1997;285-288.
    • (1997) Nature , vol.387 , pp. 285-288
    • Joerges, J.1    Küttner, A.2    Galizia, C.G.3    Menzel, R.4
  • 61
    • 0033595793 scopus 로고    scopus 로고
    • A systems perspective on early olfactory coding
    • Laurent G. A systems perspective on early olfactory coding. Science. 286:1999;723-728.
    • (1999) Science , vol.286 , pp. 723-728
    • Laurent, G.1
  • 62
    • 0030219766 scopus 로고    scopus 로고
    • Olfactory mechanisms in Drosophila melanogaster
    • Smith D.P. Olfactory mechanisms in Drosophila melanogaster. Curr Opin Neurobiol. 6:1996;500-505.
    • (1996) Curr Opin Neurobiol , vol.6 , pp. 500-505
    • Smith, D.P.1
  • 63
    • 0033595225 scopus 로고    scopus 로고
    • Circadian rhythms in olfactory responses of Drosophila melanogaster
    • The authors demonstrate that olfactory sensitivity is increased during periods of subjective night. These rhythms of olfactory function persist in constant darkness and are sensitive to mutations that disrupt circadian rhythms of locomotor activity.
    • Krishnan B., Dryer S.E., Hardin P.E. Circadian rhythms in olfactory responses of Drosophila melanogaster. Nature. 400:1999;375-378. The authors demonstrate that olfactory sensitivity is increased during periods of subjective night. These rhythms of olfactory function persist in constant darkness and are sensitive to mutations that disrupt circadian rhythms of locomotor activity.
    • (1999) Nature , vol.400 , pp. 375-378
    • Krishnan, B.1    Dryer, S.E.2    Hardin, P.E.3
  • 65
    • 0034629130 scopus 로고    scopus 로고
    • Correlates of sleep and waking in Drosophila melanogaster
    • Shaw P.J., Cirelli C., Greenspan R.J., Tononi G. Correlates of sleep and waking in Drosophila melanogaster. Science. 287:2000;1834-1837.
    • (2000) Science , vol.287 , pp. 1834-1837
    • Shaw, P.J.1    Cirelli, C.2    Greenspan, R.J.3    Tononi, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.