Radiolabeled estradiol derivatives to predict response to hormonal treatment in breast cancer: A review

European Journal of Nuclear Medicine

Volumn 27, Issue 9, 2000, Pages 1421-1433

  Van de Wiele, Christophe ^a   De Vos, Filip ^b   Slegers, Guido ^b   Van Belle, Simon ^a   Dierckx, Rudi Andre ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

Author keywords

Prediction; Radiolabeled estradiol; Response

Indexed keywords

ESTRADIOL DERIVATIVE; ESTRADIOL RECEPTOR; HORMONE; RADIOISOTOPE;

BREAST CANCER; CANCER HORMONE THERAPY; DRUG RECEPTOR BINDING; DRUG UPTAKE; HORMONE RECEPTOR INTERACTION; HUMAN; ISOTOPE LABELING; RECEPTOR AFFINITY; REVIEW; TREATMENT OUTCOME;

BINDING SITES; BREAST NEOPLASMS; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR MODULATORS; FEMALE; HUMANS; RADIOLIGAND ASSAY; RECEPTORS, ESTROGEN; TAMOXIFEN;

EID: 0033864602     PISSN: 03406997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002590000305     Document Type: Review

References (129)

1. Cancer statistics
2. Epidemiology of breast cancer
3. The effects of estrogens and antiestrogens on hormone responsive human breast cancer in long term tissue culture
4. Estrogen responsive proliferation of clonal human breast carcinoma in athymic mice
5. Effect of estrogens and antiestrogens on growth of human breast cancer cells in athymic mice
6. Breast cancer in mothers prescribed diethylstilbestrol in pregnancy
7. Estrogens and the risk of breast cancer
8. Characterization and therapeutic use of hormone dependency of breast cancer
9. Endocrine aspects of the clinical management of breast cancer - Current issues
10. Hormonal therapy of breast cancer
11. Effects of tamoxifen on cell cycle progression of synchronous MCF-7 human mammary carcinoma cells
12. Steroids, steroid antagonists and cell cycle progression
13. Adjuvant endocrine therapy for operable breast cancer
14. Tamoxifen for early breast cancer: An overview of the randomised trials
15. Estrogen receptors and breast cancer response to adrenalectomy
16. Oestrogen receptors and breast cancer: Current status
17. Hormone receptors: Their role in predicting prognosis and response to endocrine therapy
18. Progestin action and progesterone receptor structure in human breast cancer: A review
19. Estrogen receptors and hormone dependency in human breast cancer
20. Establishment of uniformity in steroid receptor determinations for protocol B-09 of the National Surgical Adjuvant Breast Project
21. Revision of the standards for the assessment of hormone receptors in human breast cancer
22. Estrogen receptor as an independent prognostic factor for early recurrence in breast cancer
23. Monoclonal antibodies localize estrogen receptor in the nuclei of the target cells
24. The use of monoclonal antibodies to estrogen receptors for immunoperoxidase detection of ER in paraffin sections of human breast cancer
25. Estrogen receptor analysis on biopsies and fine needle aspirates from human breast carcinoma. Correlation of biochemical and immunohistochemical methods using monoclonal antireceptor antibodies
26. Immunohistochemical determination of estrogen and progesterone receptor status in breast cancer
27. Prognostic and predictive factors
28. Prognostic and predictive factors in breast cancer by immunohistochemical analysis
29. NIH consensus development conference on steroid receptors in breast cancer
30. Antiestrogens: Mechanisms of action and resistance in breast cancer
31. Mechanisms of hormone resistance in breast cancer
32. Assessment of response to therapy in advanced breast cancer
33. The bone scan and breast cancer
34. Iodohexestrols. II. Characterization of the binding and estrogenic activity of iodinated hexestrol derivatives in vitro and in vivo
35. 18F)-fluoroestradiols: Selective receptor based PET imaging agents
36. Preparation of four fluorine-18-labeled estrogens and their selective uptake in target tissues of immature rats
37. 18F)fluo ronorhexestrol): A positron emitting estrogen that shows highly selective, receptor-mediated uptake by target tissues in vivo
38. 11β-Methoxy-, 11β-ethyl and 17α-ethynyl-substituted 16α-fluoroestradiols: Receptor based imaging agents with enhanced uptake efficiency and selectivity
39. 18F)Fluoro)estrogens: Systematic investigation of a new series of fluorine-18-1abeled estrogens as potential imaging agents for estrogen-receptor-positive breast tumors
40. 18F)Fluoromoxestrol: A potent, metabolically stable positron emission tomography imaging agent for estrogen receptor positive human breast tumors
41. 125I)-16-iodoestradiol: Effect on estrogen receptor-mediated target tissue uptake
42. 125I)Iodo-11β-methoxy-17β-estradiol: A radiochemical probe for estrogen-sensitive tissue
43. 125I)iodo19-norpregna-1,3,5(10),20tetraene-3,17 β-diol
44. 125I)iodovinyl estradiol: An estrogen-receptor seeking radiopharmaceutical
45. 125I)-11β-methoxy-19-norpregna-1,3,5(10)20-tet raene-3,17β-diol(17α-(iodovinyl) estradiol derivatives as high specific activity potential radiopharmaceuticals
46. Synthesis, receptor binding and biodistribution of the gem-21-chloro-21-iodovinylestradiol derivatives
47. 125I)iodovinylestradiols: Effect on receptor binding and receptor-mediated target tissue uptake
48. 123I) NIVE)
49. Novel high-affinity steroidal estrogenic ligands: Synthesis and receptor binding of 11β-vinyl-17α-E/Z-phenylselenovinyl estradiols
50. 18F)fluorodoisynolic acids
51. Carbon-11-labeled estrogens as potential imaging agents for breast tumors
52. 123I)-labeled Z-17α-iodovinyl-11β-chloromethyl-estradiol
53. 3H)estradiol-17β: A very high affinity, reversible ligand for the estrogen receptor
54. Improvement of the tissular distribution of Z-CMIV, a high specific estrogen receptor seeking steroid by means of molecular encapsulation
55. The testing of putative receptor binding radiotracers in vivo
56. Identifiability analysis of an in vivo receptor-binding radiopharmacokinetic system
57. Endogenous concentration and subcellular distribution of estrogens in normal and malignant breast tissue
58. Aromatase 17β hydroxy-steroid dehydrogenase and intratissular sex hormone concentration in cancerous and normal glandular breast tissue in postmenopausal women
59. Human mammary cancer as a site of sex steroid metabolism
60. Role of human adipose tissue in the production and metabolism of steroid hormones
61. Estrogen in tissues: Uptake from the peripheral circulation or local production
62. Comparisons of radioiodoestradiol blood-tissue exchange after intravenous or intra-arterial injection
63. 3H-oestradiol by normal breast and breast tumor tissue in postmenopausal women
64. Oestrogen uptake and metabolism in vivo
65. Comparison of levels of cytosol estrogen receptors with arterial and venous concentrations of gonadal steroids in mammary tumors
66. Estrogen receptors in hormone-responsive tissue and tumors
67. Oestrogen receptors and breast cancer: Current status
68. Hormone receptor assays: Clinical usefulness in the management of carcinoma of the breast
69. Sex hormone-binding globulin: Not only a transport protein. What news is around the corner?
70. Sex steroid binding protein (SBP) receptors in estrogen sensitive tissues
71. Biological relevance of the interaction between sex steroid binding protein and its specific receptor of MCF-7 cells: Effect on the estradiol-induced cell proliferation
72. Intracellular sex hormone-binding globulin (SHBG) in normal and neoplastic breast tissue: An additional marker for hormone dependency?
73. Characterization of membrane estrogen binding proteins from rabbit uterus
74. Characterization of estrogen and antiestrogen binding to the cytosol and microsomes of breast tumors
75. ERβ: Identification and characterisation of a novel human estrogen receptor
76. Human estrogen receptor β-gene structure, chromosomal localisation and expression pattern
77. Estrogen receptor β - A new dimension in estrogen mechanism of action
78. Expression of estrogen receptor-beta in human breast tumors
79. Cloning of a novel receptor expressed in rat prostate and ovary
80. Identification of estrogen receptor beta2, a functional variant of estrogen receptor beta expressed in normal rat tissues
81. Expression of estrogen receptor beta messenger RNA variant in breast cancer
82. Mechanism for maintenance of high breast tumor estradiol concentrations in the absence of ovarian function: Role of very high affinity tissue uptake
83. Receptor binding studies
84. Expression of hydroxysteroid sulphotransferase is related to estrogen receptor status in human mammary cancer
85. Estradiol esters can replace 17-beta-estradiol in the stimulation of DNA and esterase synthesis by MCF-7 cells: A possible role for the estrogen-sensitive MCF-7 cell esterase
86. Relationship between tumour aromatase activity, tumour characteristics and response to therapy
87. Steroid metabolism in breast cancer
88. Oestradiol synthesis from C19 steroids by human breast cancer
89. Aromatase activity in normal breast and breast tumour tissues: In vivo and in vitro studies
90. The conversion of androstenedione to estrone, estradiol and testosterone in breast tissue
91. Comparison of the in vitro conversion of estradiol to estrone in normal and neoplastic human breast tissue
92. Metabolic fate of estradiol in human mammary cancer cells in culture: Estrogen sulfate formation and cooperativity exhibited by estrogen sulfotransferase
93. Metabolism of lipoidal derivatives of estradiol-17-beta in human mammary cancer tissue and cell lines
94. Estrone sulfatase activity and effect of antiestrogens on transformation of estrone sulfate in hormone-dependent vs. independent human breast cancer cell lines
95. Control and expression of oestrone sulphatase activities in human breast cancer
96. Concentrations of oestrone and 4-hydroxyandrostenedione in malignant and normal breast tissue
97. The relevance of local oestrogen metabolism within the breast
98. The relationship between 17-hydroxysteroid dehydrogenase activity and oestrogen concentration in human breast tumours and in normal breast
99. Recent data on estrogen sulfatases and sulfotransferases activities in human breast cancer
100. Regulation of estrogen sulfotransferase by estrogen in MCF-7 human mammary cancer cells
101. Determinants of tissue estradiol levels and biologic responsiveness in breast tumors
102. 77Br)Bromoestradiol-17β: A high specific-activity, gamma-emitting tracer with uptake in rat uterus and induced mammary tumors
103. 77Br)Bromoestradiol-17β: Dosimetry and preliminary clinical studies
104. 125I)iodoestradiol-17β
105. 2)
106. Breast cancer imaging with radioiodinated oestradiol
107. 123J-markiertem Ostradiol beim Mammakarzinom-rezeptorszintigraphie
108. Images of estrogen-receptor-positive breast tumors produced by estradiol labeled with iodine I 123 at 16α
109. Radiochemistry and radiopharmaceuticals
110. 18F)fluoro 17β-estradiol in DMBA-induced mammary tumors
111. Breast cancer: PET imaging of estrogen receptors
112. 18F)fluoro 17β-estradiol uptake in metastatic breast carcinoma
113. Positron tomographic assessment of estrogen receptors in breast cancer: Comparison with FDG-PET and in vitro receptor assays
114. Clinical correlation of FDG and FES-PET imaging with estrogen receptors in breast cancer and response to systemic therapy
115. 123I)iodovinylestradiol: An estrogen-receptor-seeking radiopharmaceutical
116. 125I)-iodovinyl-11β-methoxyestradiol, an estrogen receptor-binding radiopharmaceutical in human breast cancer cells (MCF-7)
117. 2). Part I. Radiotracer preparation and characterization
118. 123I)iodovinylestradiol is a promising radioligand for estrogen receptor imaging in human breast cancer
119. Imaging of estrogen receptors in primary and metastatic breast cancer patients with iodine-123-labeled Z-MIVE
120. 123I)iodovinylestradiol in healthy women and breast cancer patients
121. Behaviour of vaginal epithelial maturation and sex hormone binding globulin in post-menopausal breast cancer patients during the first year of tamoxifen therapy
122. Effects of tamoxifen adjuvant therapy and a low-fat diet on serum binding proteins and estradiol bioavailability in postmenopausal breast cancer patients
123. Influence of tamoxifen on sex hormones, gonadotrophins and sex hormone binding globulin in postmenopausal breast cancer patients
124. Recent data on estrogen sulfatases and sulfotransferases activities in human breast cancer
125. Estrone sulfatase versus estrone sulfotransferase in human breast cancer: Potential clinical applications
126. Effect of Org OD14 (LIVIAL) and its metabolites on human estrogen sulphotransferase activity in the hormone-dependent MCF-7 and T-47D, and the hormone-independent MDA-MB-231, breast cancer cell lines
127. Positron emission tomographic assessment of 'metabolic flare' to predict response of metastatic breast cancer to antiestrogen therapy
128. Can Z-MIVE scintigraphy predict response to antiestrogen treatment in metastasized ER-positive breast cancer [abstract]?