Effect of Org OD14 (LIVIAL®) and its metabolites on human estrogen sulphotransferase activity in the hormone-dependent MCF-7 and T-47D, and the hormone-independent MDA-MB-231, breast cancer cell lines

Anticancer Research

Volumn 19, Issue 1 A, 1999, Pages 269-275

  Chetrite, Gerard Samuel ^a   Kloosterboer, Helenius Jan ^b   Philippe, Jean Claude ^a   Pasqualini, Jorge Raul ^a  

^a Institut de Puericulture   (France)

^b AKZO NOBEL CENTRAL RESEARCH   (Netherlands)

Author keywords

Breast cancer; Org OD14; Sulphotransferase

Indexed keywords

DRUG METABOLITE; ESTRADIOL; ESTROGEN; ESTRONE; SULFATE; SULFOTRANSFERASE; TIBOLONE; TRITIUM;

ARTICLE; BIOSYNTHESIS; BREAST CANCER; CELL STRAIN MCF 7; CULTURE MEDIUM; HORMONE SUBSTITUTION; HORMONE SYNTHESIS; HUMAN; HUMAN CELL; INCUBATION TIME; POSTMENOPAUSE; PRIORITY JOURNAL; TEMPERATURE;

ANTINEOPLASTIC AGENTS, HORMONAL; BREAST NEOPLASMS; ESTROGENS; ESTRONE; FEMALE; HUMANS; NEOPLASMS, HORMONE-DEPENDENT; NORPREGNENES; SULFOTRANSFERASES; TUMOR CELLS, CULTURED;

EID: 0032921646     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Pasqualini JR, Chetrite G, and Le Nestour E: Control and expression of oestrone sulphatase activities in human breast cancer. J Endocr 150: S99-S105, 1996a.
2. Pasqualini JR, Chetrite G, Blacker C, Feinstein M-C, Delalonde L, Talbi M, and Maloche C: Concentrations of estrone, estradiol, and estrone sulfate and evaluation of sulfatase and aromatase activities in pre-and postmenopausal breast cancer. J Clin Endocr Metab 81: 1460-1464, 1996b.
3. Pasqualini JR, and Chetrite G: Activity, regulation and expression of sulfatase, sulfotransferase and 17ß-hydroxysteroid dehydrogenase in breast cancer, In: Hormone-dependent Cancer (Pasqualini JR, and Katzenellenbogen BS, eds). New York, Marcel Dekker Inc., 1996, pp 25-80.
4. Godefroi VC, Locke ER, Singh DV, and Brooks SC: The steroid alcohol and estrogen sulfotransferases in rodent and human mammary tumors. Cancer Res 35: 1791-1798, 1975.
5. Raju U, Blaustein A, and Levitz M: Conjugation of androgens and estrogens by human breast tumors in vitro. Steroids 35: 685-695, 1980.
6. Pasqualini JR: Steroid sulphotransferase activity in human hormone-independent MDA-MB-468 mammary cancer cells. Eur J Cancer 28A: 758-762, 1992.
7. Adams JB, Philips NS, and Hall R: Metabolic fate of estradiol in human mammary cancer cells in culture: estrogen sulfate formation and cooperativity exhibited by estrogen sulfotransferase. Molec Cell Endocr 58: 231-242, 1988.
8. Falany JL, and Falany CN: Expression of cytosolic sulfotransferases in normal mammary epithelial cells and breast cancer cell lines. Cancer Res 56: 1551-1555, 1996a.
9. Anderson E, and Howell A: Oestrogen sulphotransferases in malignant and normal human breast tissue. Endocrine-Related Cancer 2: 227-233, 1995.
10. Bernier F, Leblanc G, Labrie F, and Luu-The V: Structure of human estrogen and aryl sulfotransferase gene. J Biol Chem 269: 28200-28205, 1994.
11. Luu-The V, Bernier F, and Dufort I: Steroid sulfotransferases. J Endocr 150: S87-S97, 1996.
12. Falany CN, Wheeler J, Oh TS, and Falany JL: Steroid sulfation by expressed human cytosolic sulfotransferases. J Steroid Biochem Molec Biol 48: 369-375, 1994.
13. Kicovic PM, Cortes-Prieto J, Luisi M, and Franchi F: Placebo-controlled cross-over study of the effects of Org OD 14 in menopausal women. Reproduction 6: 81-91, 1982.
14. Bjarnason N, Bjarnason K, Haarbo J, and Christiansen C: Tibolone: prevention of bone loss in late postmenopausal women. J Clin Endocr Metab 81: 2419-2422, 1996.
15. Chetrite G, Kloosterboer HJ, and Pasqualini JR: Effect of tibolone (Org OD14) and its metabolites on estrone sulphatase activity in MCF-7 and T-47D mammary cancer cells. Anticancer Res 77: 135-140, 1997.
16. Chetrite GS, Kloosterboer HJ. Philippe J-C, and Pasqualini JR: Effect of Org OD14 (Livial®) and its metabolites on 17ß-hydroxysteroid dehydrogenase activity in the hormone-dependent MCF-7 and T-47D breast cancer cells. Submitted, 1998.
17. Burton K: A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. Biochem J 62: 315-323, 1956.
18. Chetrite G, and Pasqualini JR: Steroid sulphotransferase and 17ß-hydroxysteroid dehydrogenase activities in Ishikawa human endometrial adenocarcinoma cells. J Steroid Biochem Molec Biol 61: 27-34, 1997.
19. Urabe M, Chetrite G, and Pasqualini JR: Transformation of estrone, estradiol, and estrone sulfate in uterine and vaginal isolated cells of fetal guinea pig. Effect of various antiestrogens in the conversion of estrone sulfate to estradiol. Steroids 58: 209-214, 1993.
20. Santner SJ, Feil PD, and Santen RJ: In situ estrogen production via the estrone sulfatase pathway in breast tumors: relative importance versus the aromatase pathway. J Clin Endocr Metab 59: 29-33, 1984.
21. Pasqualini JR, Gelly C, and Lecerf F: Biological effects and morphological responses to estriol, estriol-3-sulfate, estriol-17-sulfate and tamoxifen in a tamoxifen-resistant cell line (R-27) derived from MCF-7 human breast cancer cells. Eur J Cancer Clin Oncol 22: 1495-1501, 1986.
22. MacIndoe JH, with the technical assistance of G Woods, L Jeffries, and M Hinkhouse: The hydrolysis of estrone sulfate and dehydroepiandrosterone sulfate by MCF-7 human breast cancer cells. Endocrinology 123:1281-1287, 1988.
23. Pasqualini JR, Gelly C, Nguyen B-L, and Vella C: Importance of estrogen sulfates in breast cancer. J Steroid Biochem 34: 155-163, 1989.
24. Pasqualini JR, Chetrite G, Nguyen B-L, Blacker C, Feinstein M-C, Maloche C, Talbi M, and Delalonde L: Control of estrone sulfatase activity and its expression in human breast cancer. In: Sex hormones and antihormones in endocrine dependent pathology: basic and clinical aspects (Motta M and Serio M, eds). Excerpta Medica Int Congr Ser 1064: 257-265, 1994.
25. Falany CN, Krasnykh V, and Falany JL: Bacterial expression and characterization of a cDNA for human liver estrogen sulfotransferase. J Steroid Biochem Molec Biol 52: 529-539, 1995.
26. Chetrite G, Le Nestour E, and Pasqualini JR: Human estrogen sulfotransferase (hEST1) activities and its mRNA in various breast cancer cell lines. Effect of the progestin, promegestone (R-5020). J Steroid Biochem Molec Biol 66: 295-302, 1998.
27. Hobkirk R: Steroid sulfation - current concepts. Trends Endocr Metab 4: 69-74, 1993.
28. Saunders DE, Lozon MM, Corombos JD and Brooks SC: Role of porcine endometrial estrogen sulfotransferase in progesterone mediated down-regulation of estrogen receptor. J Steroid Biochem 32: 749-757, 1989.
29. Roy AK: Regulation of steroid hormone action in target cells by specific hormone-inactivating enzymes. Proc Soc Experim Biol Med 199: 265-272, 1992.
30. Nash AR, Glenn WK, Moore SS, Kerr J, Thompson AR, and Thompson EOP: Oestrogen sulfotransferase: molecular cloning and sequencing of cDNA for the bovine placental enzyme. Aust J Biol Sci 41: 507-516, 1988.
31. Kuhnz W: Pharmacokinetics of the contraceptive steroids levonorgestrel and gestodene after single and multiple oral administration to women. Am J Obstet Gynecol 163: 2120-2126, 1990.
32. Reddel RR, and Sutherland RL: Tamoxifen stimulation of human breast cancer cell proliferation in vitro: a possible model for tamoxifen tumour flare. Eur J Cancer Clin Oncol 20: 1419-1424, 1984.
33. Adams JB, Phillips NS, and Pewnim T: Expression of hydroxysteroid sulphotransferase is related to estrogen receptor status in human mammary cancer. J Steroid Biochem Molec Biol 33: 637-642, 1989.
34. Pewnim T, Adams JB, and Ho KP: Estrogen sulfurylation as an alternative indicator of hormone dependence in human breast cancer. Steroids 39: 47-52, 1982.
35. Falany JL, Lawing L, and Falany CN: Identification and characterization of cytosolic sulfotransferase activities in MCF-7 human breast carcinoma cells. J Steroid Biochem Molec Biol 46: 481-487, 1993.
36. Sharp S, Anderson JM, and Coughtrie MWH: Immunohistochemical localisation of hydroxysteroid sulphotransferase in human breast carcinoma tissue: a preliminary study. Eur J Cancer, 30A: 1654-1659, 1994.
37. Tseng L, Mazella J, Lee LY, and Stone ML: Estrogen sulfatase and estrogen sulfotransferase in human primary mammary carcinoma. J Steroid Biochem 19: 1413-1417, 1983.
38. Adams JB and Phillips NS: Properties of estrogen and hydroxysteroid sulphotransferases in human mammary cancer. J Steroid Biochem 36: 695-701, 1990.
39. Dooley TP: Cloning of the human phenol sulfotransferase gene family: three genes implicated in the metabolism of catecholamines, thyroid hormones and drugs. Chemico-Biological Interactions 109: 29-41, 1998.
40. Pasqualini JR, and Chetrite G: Control of estrone sulfatase activity in human breast cancer cells: effect of tibolone and its metabolites. Gynecol Endocrinol 11: (Suppl. 1) 69-75, 1997.
41. Chetrite G, Paris J, Botella J, and Pasqualini JR: Effect of nomegestrol acetate on estrone-sulfatase and 17ß-hydroxysteroid dehydrogenase activities in human breast cancer cells. J Steroid Biochem Molec Biol 58: 525-531, 1996.
42. Pasqualini JR, Chetrite G, Nguyen B-L, Maloche C, Delalonde L, Talbi M, Feinstein M-C, Blacker C, Botella J, and Paris J: Estrone sulfate-sulfatase and 17ß-hydroxysteroid dehydrogenase activities: a hypothesis for their role in the evolution of human breast cancer from hormone-dependence to hormone-independence. J Steroid Biochem Molec Biol 53: 407-412, 1995.
43. Pasqualini JR, Maloche C, Maroni M, and Chetrite G: Effect of the progestagen Promegestone (R-5020) on mRNA of the oestrone sulphatase in the MCF-7 human mammary cancer cells. Anticancer Res 14: 1589-1594, 1994.
44. Pack BA, Booth TE, and Brooks SC: The cyclic relationship of estrogen sulfurylation to the nuclear receptor level in human endometrial curettings. J Clin Endocr Metab 48: 420-424, 1979.
45. Buirchell BJ, and Hähnel R: Metabolism of estradiol-17ß in human endometrium during the menstrual cycle. J Steroid Biochem 6: 1489-1494, 1975.
46. Clarke CL, Adams JB, and Wren BG: Induction of cestrogen sulfotransferase activity in the human endometrium by progesterone in organ culture. J Clin Endocr Metab 55: 70-75, 1982.
47. Tseng L, and Liu HC: Stimulation of arylsulfotransferase activity by progestins in human endometrium in vitro. J Clin Endocr Metab 53: 418-421, 1981.
48. Falany JL, and Falany CN: Regulation of estrogen sulfotransferase in human endometrial adenocarcinoma cells by progesterone. Endocrinology 137: 1395-1401, 1996.
49. Adams JB, Vrahimis R, and Phillips N: Regulation of estrogen sulfotransferase by estrogen in MCF-7 human mammary cancer cells. Breast Cancer Res Treat 22: 157-161, 1992.