Islet xenograft destruction in the hu-PBL-severe combined immunodeficient (SCID) mouse necessitates anti-CD3 preactivation of human immune cells

Clinical and Experimental Immunology

Volumn 121, Issue 3, 2000, Pages 557-565

  Gysemans, C ^a   Waer, M ^a   Laureys, J ^a   Depovere, J ^a   Pipeleers, D ^a,b   Bouillon, R ^a   Mathieu, C ^a,c  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b DIABETES RESEARCH CENTER   (Belgium)

^c LEGENDO   (Belgium)

Author keywords

Anti CD3 activation; Destruction; Hu PBL SCID; Mouse; Pancreatic islets; Xenograft

Indexed keywords

ANTIBODY; C PEPTIDE; CD3 ANTIGEN; GLUCOSE; INSULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GLUCOSE TOLERANCE; GRAFT REJECTION; HYPERGLYCEMIA; IMMUNE SYSTEM; IMMUNOCOMPETENT CELL; IMMUNOREGULATION; IMMUNOSTIMULATION; LYMPHOCYTIC INFILTRATION; MOUSE; NONHUMAN; PANCREAS INJURY; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; SCID MOUSE;

ANIMALS; ANTIGENS, CD3; CHIMERA; DIABETES MELLITUS, EXPERIMENTAL; GRAFT REJECTION; HUMANS; ISLETS OF LANGERHANS TRANSPLANTATION; LYMPHOCYTE ACTIVATION; LYMPHOCYTE TRANSFUSION; MALE; MICE; MICE, SCID; RATS; RATS, INBRED BB; SEVERE COMBINED IMMUNODEFICIENCY; TRANSPLANTATION, HETEROLOGOUS;

EID: 0033863694     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.2000.01300.x     Document Type: Article

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