Gastrin-releasing peptide is a mitogen and a morphogen in murine colon cancer

Cell Growth and Differentiation

Volumn 11, Issue 7, 2000, Pages 385-393

  Carroll, Robert E ^a,b   Matkowskyj, Kristina A ^a,b   Tretiakova, Maria S ^a,b   Battey, James F ^a,c   Benya, Richard V ^a,b  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b JESSE BROWN VA MEDICAL CENTER   (United States)

^c NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZOXYMETHANE; FOCAL ADHESION KINASE; GASTRIN; GASTRIN RELEASING PEPTIDE; MITOGENIC AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; COLON CANCER; COLON MUCOSA; CONTROLLED STUDY; EPITHELIUM CELL; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SOLID TUMOR;

ADENOCARCINOMA; ANIMALS; APOPTOSIS; AZOXYMETHANE; CARCINOGENS; CELL DIFFERENTIATION; CELL DIVISION; COLONIC NEOPLASMS; EPITHELIAL CELLS; FOCAL ADHESION KINASE 1; FOCAL ADHESION PROTEIN-TYROSINE KINASES; GASTRIN-RELEASING PEPTIDE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOGENS; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS PP60(C-SRC); RECEPTORS, BOMBESIN;

EID: 0033859617     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (53)

1. Kinzler, K. W., and Vogelstein, B. Lesions from hereditary colorectal cancer. Cell, 87: 159-170, 1996.
2. White, R. L. Tumor suppressing pathways. Cell, 92: 591-592, 1998.
3. c-src protein kinase is an early event in colonic carcinogenesis. Proc. Natl. Acad. Sci. USA, 87: 558-562, 1990.
4. Rosai, J. Principles of oncologic pathology. In: V. T. DeVita, Jr., S. Hellman, and S. A. Rosenberg (eds.), Cancers: Principles and Practice of Oncology, pp. 228-237. Philadelphia: J. B. Lippincott Co., 1993.
5. Shepherd, N. A., Saraga, E-P., Love, S. B., and Jass, J. R. Prognostic factors in colonic cancer. Histopathology, 14: 613-620, 1989.
6. Steinberg, S. M., Barwick, K. W., and Stablein, D. M. Importance of tumor pathology and morphology in patients with surgically resected colon cancer. Cancer (Phila.), 58: 1340-1345, 1986.
7. Carroll, R. E., Matkowskyj, K. A., Chakrabarti, S., McDonald, T. J., and Benya, R. V. Aberrant expression of gastrin-releasing peptide and its receptor by well differentiated colon cancers in humans. Am. J. Physiol., 276: G655-G665, 1999.
8. King, K. A., Torday, J. S., and Sunday, M. E. Bombesin and [Leu8]phyllolitorin promote fetal mouse lung branching morphogenesis via a receptor-mediated mechanism. Proc. Natl. Acad. Sci. USA, 92: 4357-4361, 1995.
9. Wang, D., Yeger, H., and Cutz, E. Expression of gastrin-releasing peptide receptor gene in developing lung. Am. J. Respir. Cell Mol. Biol., 14: 409-416, 1996.
10. Cuttitta, F., Carney, D. N., Mulshine, J., Moody, T. W., Fedorko, J., Fishier, A., and Minna, J. D. Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer cells. Nature (Lond), 316: 823-826, 1985.
11. Vigna, S. R., Mantyh, C. R., Giraud, A. S., Soll, A. H., Walsh, J. H., and Mantyh, P. W. Localization of specific binding sites for bombesin in the canine gastrointestinal tract. Gastroenterology, 93: 1287-1295, 1987.
12. Kato, M., Yamada, H., Kawata, M., Takeyama, M., Hitomi, S., Yajima, H., and Sano, Y. Immunohistochemical study of gastrin-releasing peptide-containing peripheral nerve fibers in rat, macaque and human. J. Auton. Nerv. Syst., 35: 161-168, 1991.
13. Bitar, K. N., and Zhu, X. X. Expression of bombesin-receptor subtypes and their differential regulation of colonic smooth muscle contraction. Gastroenterology, 105: 1672-1680, 1993.
14. Battey, J. F., Way, J. M., Corjay, M. H., Shapira, H., Kusano, K., Harkins, R., Wu, J. M., Slattery, T., Mann, E., and Feldman, R. I. Molecular cloning of the bombesin/gastrin-releasing peptide receptor from Swiss 3T3 cells. Proc. Natl. Acad. Sci. USA, 88: 395-399, 1991.
15. Ferris, H. A., Carroll, R. E., Lorimer, D. L., and Benya, R. V. Location and characterization of the human GRP receptor expressed by gastrointestinal epithelial cells. Peptides, 18: 663-672, 1997.
16. Radulovic, S., Miller, G., and Schally, A. V. Inhibition of growth of HT-29 human colon cancer xenografts in nude mice by treatment with bombesin/gastrin releasing peptide antagonist (RC-3095). Cancer Res., 51: 6006-6009, 1991.
17. Frucht, H., Gazdar, A., and Jensen, R. T. human colon cancer cell line NCI-H716 expresses functional bombesin receptors. Proc. Am. Assoc. Cancer Res., 32: 47-52, 1991.
18. Narayan, S., Guo, J. S., Townsend, C. M., and Singh, P. Specific binding and growth effects of bombesin-related peptides on mouse colon cancer cells in vitro. Cancer Res., 50: 6772-6778, 1990.
19. Frucht, H., Gazdar, A. F., Park, J. A., Oie, H., and Jensen, R. T. Characterization of functional receptors for gastrointestinal hormones on human colon cancer cells. Cancer Res., 52; 1114-1122, 1992.
20. Radulovic, S., Schally, A. V., Reile, H., Halmos, G., Szepeshazi, K., Groot, K., Milovanovic, S., Miller, G., and Yano, T. Inhibitory effects of antagonists of bombesin/gastrin releasing peptide (GRP) and somatostatin analog (RC-160) on growth of HT-29 human coton cancers in nude mice. Acta Oncol., 33: 693-701, 1994.
21. Hampton, L. L., Ladenheim, E. E., Akeson, M., Way, J. M., Weber, H. C., Sutliff, V. E., Jensen, R. T., Wine, L. J., Arnheiter, H., and Battey, J. F. Loss of bombesin-induced feeding suppression in gastrin-releasing peptide receptor-deficient mice. Proc. Natl. Acad. Sci. USA, 95: 3188-3192, 1998.
22. Rogers, A. E., and Nauss, K. M. Rodent models for carcinoma of the colon. Dig. Dis. Sci., 30: 87S-102S, 1985.
23. Matkowskyj, K. A., Marrero, J. A., Carroll, R. E., Danilkovich, A. V., Green, R. M., and Benya, R. V. Azoxymethane-induced fulminant hepatic failure in C57BL/6J mice: characterization of a new animal model. Am. J. Physiol., 277: G455-G462, 1999.
24. Izumi, K., Otsuka, H., Furuya, K., and Akagi, A. Carcinogenicity of 1,2-dimethylhydrazine dihydrochloride in BALB/c mice. Virchows Archiv. A Pathol. Anat. Histol., 384: 263-267, 1979.
25. Haase, P., Cowen, D. M., Knowles, J. C., and Cooper, E. H. Evaluation of dimethylhydrazine induced tumours in mice as a model system for colorectal cancer. Br. J. Cancer, 28: 530-543, 1973.
26. c- SCR activity in well and poorly differentiated human colon carcinomas and cell lines. J. Clin. Investig., 90: 815-821, 1992.
27. Willey, J. C., Lechner, J. F., and Harris, C. C., Bombesin and the C-terrninal tetradecapeptide of gastrin-releasing peptide are growth factors for normal human bronchial epithelial cells. Exp. Cell Res., 153: 245-258, 1984.
28. Hajri, A., Balboni, G., Koenig, M., Garaud, J-G., and Damge, C. Gastrin-releasing peptide: in vivo and in vitro growth effects on an acinar pancreatic carcinoma. Cancer Res., 52: 3726-3732, 1992.
29. Yano, T., Pinski, J., Groot, K., and Schally, A. V. Stimulation by bombesin and inhibition by bombesin/gastrin-releasing peptide antagonist RC-3095 of growth of human breast cancer cell lines. Cancer Res., 52: 4545-4547, 1992.
30. Giacchetti, S., Gauville, C., De Cremoux, P., Bertin, L., Berthon, P., Abita, J-P., Cuttitta, F., and Calvo, F. Characterization, in some human breast cancer cell lines, of gastrin-releasing peptide-like receptors which are absent in normal breast epithelial cells. Int. J. Cancer, 46: 293-298, 1990.
31. Halmos, G., Wittliff, J. L., and Schally, A. V. Characterization of bombesin/gastrin-releasing peptide receptors in human breast cancer and their relationship to steroid receptor expression. Cancer Res., 55: 280-287, 1995.
32. Moody, T. W., Carney, D. N., Cuttitta, F., Quattrocchi, K., and Minna, J. D. High affinity receptors for bombesin/GRP-like peptides on human small cell lung cancer. Life Sci., 37: 105-113, 1985.
33. Moody, T. W., and Korman, L. Y. The release of bombesin-like peptides from small cell lung cancer cells. In: Y. Tache, P. Melchiorri, and L. Negri (eds.), Bombesin-like Peptides in Health and Disease, pp. 351-359. New York: Academy of Sciences, 1988.
34. Nakajima, T., Shimosato, Y., Morinaga, S., Terasaki, T., Tsumuraya, M., Yamaguchi, K., Ichinose, H., Nagatsu, T., Kato, K., and Nakazato, Y. Immunohistochemical study of small cell lung carcinoma: with special reference to the neuroendocrine markers aromatic L-amino acid decarboxylase and gastrin-releasing peptide. Jpn. J. Clin. Oncol., 16: 223-233, 1986.
35. Carney, D. N., Gazdar, A. F., Bepler, G., Guccion, J. G., Marangos, P. J., Moody, T. W., Zweig, M. H., and Minna, J. D. Establishment and identification of small cell lung cancer cell lines having classic and variant features. Cancer Res., 45: 2913-2923, 1985.
36. Kado-Fong, H., and Malfroy, B. Effects of bombesin on human small cell lung cancer cells: evidence for a subset of bombesin non-responsive cell lines. J. Cell Biochem., 40: 431-437, 1989.
37. Bartholdi, M. F., Wu, J. M., Pu, H., Troncoso, P., Eden, P. A., and Feldman, R. I. In situ hybridization for gastrin-releasing peptide receptor (GRP receptor) expression in prostatic carcinoma. Int. J. Cancer, 79: 82s-90s, 1998.
38. Markwalder, R., and Reubi, J. C. Gastrin-releasing peptide receptors in the human prostate: relation to neoplastic transformation. Cancer Res., 59: 1152-1159, 1999.
39. Symonds, D. A., and Vickery, A. L. Mucinous carcinoma of the colon and rectum. Cancer (Phila.), 37: 1891-1900, 1976.
40. Bresalier, R. S., Niv, Y., Byrd, J. C., Dun, Q-Y., Toribara, N. W., Rockwell, R. W., Dahiya, R., and Kim, Y. S. Mucin production by human colonic carcinoma cells correlates with their metastatic potential in animal models of colon cancer metastasis. J. Clin. Investig. 87: 1037-1045, 1991.
41. Nakagawa, K., Sogo, S., Hioki, K., Tokunaga, R., and Taketani, S. Acquisition of cell adhesion and induction of focal adhesion kinase of human colon cancer Colo 201 cells by retinoic acid-differentiation. Differentiation, 62: 249-257, 1989.
42. Levy, P., Robin, H., Kornprobst, M., Capeau, J., and Cherqui, G. Enterocytic differentiation of the human Caco-2 cell line correlates with alterations in integrin signaling. J. Cell Physiol., 177: 618-627, 1998.
43. Tami, T., von Koskul, H., and Virtanen, I. Focal adhesion kinase pp125FAK is associated with both intercellular junctions and matrix adhesion sites in vivo. Histochem. Cell Biol., 105: 17-25, 1996.
44. FAK): a point of convergence in the action of neuropeptides, integrins, and oncogenes. Cell, 71: 891-894, 1992.
45. Leeb-Lundberg, L. M., and Song, X-H. Identification of p125, a component of a group of 120-kDa proteins that are phosphorylated on tyrosine residues in response to bradykinin and bombesin stimulation, in anti-ras-GTPase-activating protein immunoprecipitates of Swiss 3T3 cells. J. Biol. Chem., 268: 8151-8157, 1993.
46. 2+ mobilization, and the actin cytoskeleton. J. Biol. Chem., 268: 14261-14268, 1993.
47. Yang, H. K., Scott, F. M., Trepel, J. B., Battey, J. F., Johnson, B. E., and Kelley, M. J. Correlation of expression of bombesin-like peptides and receptors with growth inhibition by an anti-bombesin antibody in small-cell lung cancer cell lines. Lung Cancer, 21: 165-175, 1998.
48. Frie, E., Whang, J., Scoggins, R. B., Van Scott, E. J., Rall, D. P., and Ben, M. The stathmokinetic effect of vincristine. Cancer Res., 24: 1918-1925, 1964.
49. Goodlad, R. A., Levi, S., Lee, C. Y., Mandir, N., Hodgson, H., and Wright, N. A. Morphometry and cell proliferation in endoscopic biopsies: evaluation of a technique. Gastroenterology, 101: 1235-1241, 1991.
50. Baak, J. P. A. Mitosis counting in tumors. Hum. Pathol., 21: 683-685, 1990.
51. Large bowel polyps and tumors. In: K. J. Lewin, R. H. Riddell, and W. M. Weinstein (eds.), Gastrointestinal Pathology and Its Clinical Implications, pp. 1198-1317. New York: Igaku-Shoin, 1992.
52. Matkowskyj, K. A., Schonfeld, D., and Benya, R. V. Quantitative immunohistochemistry by measuring cumulative signal strength using commercially available software Photoshop and Matlab. J. Histochem. Cytochem., 48: 303-311, 2000.
53. Southgate, H. W. Note on preparing Mucicarmine. J. Pathol. Bacteriol., 30: 729, 1927.