A comparison of transient outward currents in canine cardiac Purkinje cells and ventricular myocytes

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 279, Issue 2 48-2, 2000, Pages

  Han, Wei ^a,c   Wang, Zhiguo ^a,b   Nattel, Stanley ^a,b,c  

^a MONTREAL HEART INSTITUTE   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

Action potentials; Antiarrhythmic drugs; Cardiac arrhythmias; Molecular biology of cardiac ion channels; Potassium channel blockers; Potassium channels

Indexed keywords

4 AMINOPYRIDINE; ANTIARRHYTHMIC AGENT; HYDROGEN PEROXIDE; POTASSIUM; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; TETRYLAMMONIUM;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOG; HEART ARRHYTHMIA; HEART MUSCLE POTENTIAL; HEART REPOLARIZATION; HEART VENTRICLE WALL; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; PURKINJE CELL; PURKINJE FIBER MEMBRANE POTENTIAL;

EID: 0033857640     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.2000.279.2.h466     Document Type: Article

References (42)

1. Myocardial potassium channels: Electrophysiological and molecular diversity
2. Functional knockout of the transient outward current, long-QT syndrome, and cardiac remodeling in mice expressing a dominant-negative Kv4 α-subunit
3. Why patients with congestive heart failure die: Arrhythmias and sudden cardiac death
4. Effect of rate-dependent changes in the transient outward current on the action potential in sheep Purkinje fibers
5. Distinct transient outward potassium current (I(to)) phenotypes and distribution of fast-inactivating potassium channel α-subunits in ferret left ventricular myocytes
6. + channel mRNA in isolated ferret cardiac myocytes
7. + currents in rabbit heart Purkinje cells
8. Ionic currents in cardiac excitation
9. Sea anemone peptides with a specific blocking activity against the fast inactivation potassium channel Kv3.4
10. + channel in ventricular muscle: A molecular correlate for the transient outward current
11. The electrophysiological mechanism of ventricular arrhythmias in the long QT syndrome. Tridimensional mapping of activation and recovery patterns
12. + current in rat ventricle
13. The positive dynamic current and its inactivation properties in cardiac Purkinje fibres
14. Kv3.3b: A novel Shaw-type potassium channel expressed in terminally differentiated cerebellar Purkinje cells and deep cerebellar nuclei
15. + channels, types cf Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines
16. Transient outward currents in subendocardial Purkinje myocytes surviving in the infarcted heart
17. Suppression of neuronal and cardiac transient outward currents by viral gene transfer of dominant-negative Kv4.2 constructs
18. Ionic mechanisms of action potential prolongation in ventricular myocytes from dogs with pacing-induced heart failure
19. Influence of chloride, potassium, and tetraethylammonium on the early outward current of sheep cardiac Purkinje fibers
20. 4-Aminopyridine and the early outward current of sheep cardiac Purkinje fibers
21. Sex difference in risk of torsade de pointes with dlsotalol
22. + current in human ventricular myocytes
23. Ionic bases for electrophysiological distinctions among epicardial, midmyocardial, and endocardial myocytes from the free wall of the canine left ventricle
24. A quantitative comparison of the relation between the shape of the action potential and the pattern of stimulation in canine ventricular muscle and Purkinje fibers
25. Pharmacological response of quinidine-induced early afterdepolarizations in canine cardiac Purkinje fibres: Insights into underlying ionic mechanisms
26. Repolarization abnormalities, arrhythmia and sudden death in canine tachycardia-induced cardiomyopathy
27. Functional expression of an inactivating potassium channel cloned from human heart
28. Characterization of a Shaw-related potassium channel family in rat brain
29. Molecular biology of the voltage-gated potassium channels of the cardiovascular system
30. Cloning and tissue-specific expression of five voltage-gated potassium channel cDNAs expressed in rat heart
31. Action potential prolongation and induction of abnormal automaticity by low quinidine concentrations in canine Purkinje fibers: Relationship to potassium and cycle length
32. Cloning and functional expression of a TEA-sensitive A-type potassium channel from rat brain
33. Contributions of a transient outward current to repolarization in human atrium
34. A subpopulation of cells with unique electrophysiological properties in the deep subepicardium of the canine ventricle: The M cell
35. Molecular basis of functional diversity of voltage-gated potassium channels in mammalian brain
36. Molecular cloning and functional expression of a potassium channel cDNA isolated from a rat cardiac library
37. + current in rabbit and human atrial myocytes
38. Effects of fiecainide, quinidine, and 4-aminopyridine on transient outward and ultrarapid delayed rectifier currents in human atrial myocytes
39. + currents in adult mouse ventricular myocytes
40. Electrophysiological and pharmacological correspondence between Kv4.2 current and rat cardiac transient outward current
41. Characterization of an ultrarapid delayed rectifier potassium channel involved in canine atrial repolarization
42. Transient outward and delayed rectifier currents in canine atrium: Properties and role of isolation methods