Molecular Cloning of Leukotactin-1: A Novel Human β-Chemokine, a Chemoattractant for Neutrophils, Monocytes, and Lymphocytes, and a Potent Agonist at CC Chemokine Receptors 1 and 3

Journal of Immunology

Volumn 159, Issue 11, 1997, Pages 5201-5205

  Youn, Byung S ^a   Zhang, Shang M ^a   Lee, Eun K ^b   Park, Doo H ^b   Broxmeyer, Hal E ^a   Murphy, Philip M ^c   Locati, Massimo ^c   Pease, James E ^d   Kim, Kack K ^a   Antol, Kathleen ^e   Kwon, Byoung S ^a  

^a INDIANA UNIVERSITY   (United States)

^b Mogam Biotechnology Research Institute   (South Korea)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^d UNIVERSITY OF SHEFFIELD   (United Kingdom)

^e SAINT MARY'S COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CHEMOKINE; CALCIUM; CHEMOKINE RECEPTOR; RECOMBINANT PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CHEMOTAXIS; CHROMOSOME 17; CHROMOSOME MAP; DRUG ANTAGONISM; GENETICS; HUMAN; IMMUNOLOGY; LEUKOCYTE; LYMPHOCYTE; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; MONOCYTE; NEUTROPHIL; NUCLEOTIDE SEQUENCE; TIME;

AMINO ACID SEQUENCE; BASE SEQUENCE; CALCIUM; CHEMOKINES, CC; CHEMOTAXIS; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 17; CLONING, MOLECULAR; HUMANS; LEUKOCYTES; LYMPHOCYTES; MOLECULAR SEQUENCE DATA; MONOCYTES; NEUTROPHILS; RECEPTORS, CHEMOKINE; RECOMBINANT PROTEINS; TIME FACTORS;

EID: 0031297432     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. + T cells. Science 270:1811.
2. Wolpe, S. D., G. Davatelis, B. Sherry, B. Beutler, D. G. Hesse, H. T. Nguyen, L. L. Moldawer, C. F. Nathan, S. F. Lowry, and A. Cerami. 1988. Macrophages secrete a novel heparin-binding protein with inflammatory and neutrophil chemokinetic properties. J. Exp. Med. 167:570.
3. Graham, G. J., E. G. Wright, R. Hewick, S. D. Wolpe, N. M. Wilke, D. Donaldson, S. Lorimore, and I. B. Pragnell, 1990. Identification and characterization of an inhibitor of haemopoietic stem cell proliferation. Nature 344:442.
4. Broxmeyer, H. E., B. Sherry, L. Lu, S. Cooper, K.-O. Oh, P. Tekamp-Olson, B. S. Kwon, and A. Cerami. 1990. Enhancing and suppressing effects of recombinant murine macrophage inflammatory proteins on colony formation in vitro by bone marrow myeloid progenitor cells. Blood 76:1110.
5. Oh, K.-O., Z. Zhou, K.-K. Kim, H. Samanta, M. Fraser, Y.-J. Kim, H. E. Broxmeyer, and B. S. Kwon. 1991. Identification of cell surface receptors for murine macrophage inflammatory protein-1α. J. Immunol. 147:2978.
6. Deng, H., R. Liu, W. Ellmeier, S. Choe, D. Unutmaz, M. Burkhart, P. DiMarzio, S. Marmon, R. E. Sutton, C. M., Hill, C. B. Davis, S. C. Peiper, T. J. Schall, D. R. Littman, and N. R. Landau. 1996. Identification of a major co-receptor for primary isolates of HIV-1. Nature 381:647.
7. Alkhatib, G., C. Combadiere, C. C. Broder, Y. Feng, P. E. Kennedy, P. M. Murphy, and E. A. Berger. 1996. CC CKR5: a RANTES, MIP-1α, MIP-1β receptor as a fusion cofactor for macrophage-tropic HIV-1. Science 272:1955.
8. Wilson, S. D., P. R. Billings, P. D'Eustachio, R. E. Fournier, E. Geissler, P. A. Lalley, P. R. Burd, D. E. Housman, B. A. Taylor, and M. E. Dorf. 1990. Clustering of cytokine genes on mouse chromosome 11. J. Exp. Med 171:1301.
9. Baggiolini, M., and C. A. Dahinden. 1994. CC chemokines in allergic inflammation. Immunol. Today 15:127.
10. Orlofsky, A., M. S. Berger, and M. B. Prystowsky. 1991. Novel expression pattern of a new member of the MIP-1 family of cytokine-like genes. Cell Regul. 2:403.
11. Youn, B.-S., I. K. Jang, H. E. Broxmeyer, S. Cooper, N. A. Jenkins, D. J. Gilbert, N. G. Copeland, T. A. Elick, M. J. Fraser, Jr., and B. S. Kwon. 1995. A novel chemokine, macrophage inflammatory protein-related protein-2, inhibits colony formation of bone marrow myeloid progenitors. J. Immunol. 155:2661.
12. Coligan, J., A. Kruisbeek, D. Margulies, E. Shevach, and W. Strober, eds. 1991. Immunologic studies in humans. In Current Protocols in Immunology. Green Publishing Associates and Wiley Interscience, New York, pp. 7.1.1-7.24.4.
13. Sarefi, M., E. Garcia-Zepeda, J. MacLean, I. F. Charo, and A. D. Luster. 1997. Murine monocyte chemoattractant protein (MCP)-5: a novel CC chemokine that is a structural and functional homologue of human MCP-1. J. Exp. Med. 185:99.
14. Murphy, P. M. 1994. The molecular biology of leukocyte chemoattractant receptors. Annu. Rev. Immunol. 12:593.
15. Von Heijne, G. 1983. Patterns of amino acids near signal-sequence cleavage sites. Eur. J. Biochem. 133:17.
16. Bause, E. 1983. Structural requirements of N-glycosylation of proteins: studies with proline peptides as conformational probes. Biochem. J. 209:331.
17. Forssmann, U., M. B. Delgado, M. Uguccioni, P. Loetscher, G. Garotta, and M. Baggiolini. 1997. CKβ8, a novel CC chemokine that predominantly acts on monocytes. FEBS Lett. 408:211.
18. Nagira, M., T. Imai, K. Hieshima, J. Kusuda, M. Ridanpaa, S. Takagi, M. Nishimura, M. Kakizaki, H. Nomiyama, and O. Yoshie. 1997. Molecular cloning of a novel human CC chemokine secondary lymphoid-tissue chemokine that is a potent chemoattractant for lymphocytes and mapped to chromosome 9p13. J. Biol. Chem. 272:19518.
19. Hendrick, J. A., and A. Zlotnik. 1997. Identification and characterization of a novel β-chemokine containing six conserved cysteines. J. Immunol. 159:1589.
20. Heng, H. H., and L.-C. Tsui. 1994. FISH detection on DAPI banded chromosomes. Methods Mol. Biol. 33:35.
21. Miller, M. D., S. D. Wilson, M. E. Dorf, H. N. Seuanez, S. J. O'Brien, and M. S. Krangel. 1990. Sequence and chromosomal location of the I-309 gene: relationship to genes encoding a family of inflammatory cytokines. J. Immunol. 145:2737.
22. Opdenakker, G., P. Fiten, G. Nys, G. Froyen, N. Van Roy, F. Speleman, G. Laureys, and J. Van Damme. 1994. The human MCP-3 gene (scya 7): cloning, sequence analysis, and assignment to the C-C chemokine gene cluster on chromosome 17q11.2-q12. Genomics 21:403.
23. Combadière, C., S. K. Ahuja, and P. M. Murphy. 1995. Cloning and functional expression of a human eosinophil CC chemokine receptor. J. Biol. Chem. 270: 16491.
24. Clark-Lewis, I., K.-S. Kim, K. Rajarathnam, J.-H. Gong, B. Dewald, B. Moser, M. Baggiolini, and B. D. Sykes. 1995. Structure-activity relationships of chemokines. J. Leukocyte Biol. 57:703.