Organelle motility regulated by the cell's environment: Dissection of signaling pathways regulating movements of peroxisomes

Protoplasma

Volumn 213, Issue 1-2, 2000, Pages 18-27

  Huber, C M ^a   Saffrich, R ^a   Gorgas, K ^a   Just, W W ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

G proteins; Organelle motility; Peroxisomes; Phospholipase A2; Regulation

Indexed keywords

ARACHIDONIC ACID; BIOCHEMICAL PATHWAY; CELL MOTILITY; CELL ORGANELLE; CHO CELL; CYTOSOL; ENZYME ACTIVATION; GUANINE NUCLEOTIDE BINDING PROTEIN; LYSOPHOSPHATIDIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; PEROXISOME; PHOSPHOLIPASE A; PROTEIN KINASE C; SIGNAL TRANSDUCTION;

EID: 0033848880     PISSN: 0033183X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01280501     Document Type: Article

References (81)

1. Eyes viewed from the skin
2. 2 via GTP-binding proteins: Arachidonic acid and its metabolites as second messengers
3. Golgi membrane skeleton: Identification, localization and oligomerization of a 195 kDa ankyrin isoform associated with the Golgi complex
4. Signal transduction differences between 5-hydroxytryptamine type 2A and type 2C receptor systems
5. Phosphorylation of p34(cdc2) regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo
6. Evidence of microfilament-associated mitochondrial movement
7. Neuronal polarity: Vectorial flow precedes axon formation
8. Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution
9. G-protein-coupled receptors: Turn-ons and turn-offs
10. The simultaneous symbiotic origin of mitochondria, chloroplasts, and microbodies
11. 2+ sparks
12. 2+-dependent translocation domain with homology to PKC and GAP
13. 2
14. Golgi dispersal during microtubule disruption: Regeneration of Golgi stacks at peripheral endoplasmic reticulum exit sites
15. Identification of a small cytoplasmic ankyrin (AnkG119) in the kidney and muscle that binds βI σ-spectrin and associates with the Golgi apparatus
16. +-ATPase transport from endoplasmic reticulum to Golgi requires the Golgi spectrin-ankyrin G119 skeleton in Madin-Darby canine kidney cells
17. CLIP-115, a novel brain-specific cytoplasmic linker protein, mediates the localization of dendritic lamellar bodies
18. 2-purinergic receptors for extracellular ATP and other nucleotides
19. Molecular characterization of the 50 kD-subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis
20. The bioactive phospholipid lysophosphatidic acid is released from activated platelets
21. Overexpression of Pex15p, a phosphorylated peroxisomal integral membrane protein required for peroxisome assembly in S. cerevisiae, causes proliferation of the endoplasmic reticulum membrane
22. 2 by inducing both calcium influx and activation of protein kinase C
23. A transduction pathway associated with receptors coupled to the inhibitory guanine nucleotide binding protein G(i) that amplifies ATP-mediated arachidonic acid release
24. Organelle dynamics in lobster axons: Anterograde, retrograde and stationary mitochondria
25. 1 adenosine receptors expressed in CHO cells couple to adenylyl cyclase and to phospholipase C
26. Functional coupling of the δ-, μ- and κ-opioid receptors to mitogen-activated protein kinase and arachidonate release in Chinese hamster ovary cells
27. Characterization of a 5-HT(1B) receptor on CHO cells: Functional responses in the absence of radioligand binding
28. Peroxisomes in sebaceous glands V: Complex peroxisomes in the mouse preputial gland: Serial sectioning and three-dimensional reconstruction studies
29. Diversity and selectivity of receptor-G protein interaction
30. Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor: Study of Lck- and FynT-dependent T cell activation
31. Mechanisms controlling gene expression by nuclear calcium signals
32. Chloroplast movement
33. Distinct pathways of G(i)- and G(q)-mediated mitogen-activated protein kinase activation
34. Centractin (ARP1) associates with spectrin revealing a potential mechanism to link dynactin to intracellular organelles
35. 2 signaling cascade is involved in the regulation of peroxisomal motility in CHO cells
36. 2-purinoceptor in cultured CHO-K1 cells
37. Growth factor-like effects of lysophosphatidic acid, a novel lipid mediator
38. 2+ mobilization in human A431 cells: Structure-activity analysis
39. Peroxisomal degradation of leukotrienes by beta-oxidation from the omega-end
40. Intracellular motility: How can we all work together?
41. Intracellular calcium and cAMP regulate directional pigment movements in teleost erythrophores
42. Tools for investigating functional interactions between ligands and G protein-coupled receptors
43. 2 is coupled to hormonally, regulated release of arachidonic acid
44. 2 is phosphorylated and activated by MAP kinase
45. Regulation of the intracellular distribution of cytoplasmic dynein by serum factors and calcium
46. Calmodulin binding to and cAMP-dependent phosphorylation of kinesin light chains modulate kinesin ATPase activity
47. Mitosis
48. Dispersal of Golgi apparatus in nocodazole-treated fibroblasts is a kinesin-driven process
49. Lysophosphatidic acid: G-protein signalling and cellular responses
50. The regulation of bidirectional mitochondrial transport is coordinated with axonal outgrowth
51. Endosome dynamics regulated by a rho protein
52. Myosin II is involved in the production of constitutive transport vesicles from the TGN
53. 2 by p42 microtubule-associated protein 2 kinase and protein kinase C
54. The role of calcium in apoptosis
55. Evidence for several roles of dynein in pigment transport in melanophores
56. CLIP-170 links endocytic vesicles to microtubules
57. ER-to-Golgi transport visualized in living cells
58. Microtubule-based peroxisomal movement
59. Regulation of organelle movement in melanophores by a protein kinase A (PKA), protein kinase C (PKC), and protein phosphatase 2A (PP2A)
60. Functional coordination of microtubule and actin based motility in melanophores
61. Visualization of ER: To-Golgi transport in living cells reveals a sequential mode of action for COP II and COP I
62. A dominant-negative mutant of raf blocks mitogen-activated protein kinase activation by growth factors and oncogenic p21ras
63. 2 to the nuclear envelope and endoplasmic reticulum
64. Golgi tubule traffic and the effects of brefeldin A visualized in living cells
65. Microtubule motor complexes moving membraneous organelles
66. Actin-based organelle movement
67. Import of firefly luciferase into mammalian peroxisomes in vivo requires nucleoside triphosphates
68. Activation of the c-raf protein kinase by protein kinase C phosphorylation
69. Microtubules and microtubule motors: Mechanisms of regulation
70. Mutants of the yeast Yarrowia lipolytica defective in protein exit from the endoplasmic reticulum are also defective in peroxisome biogenesis
71. Expression of a cloned rat histamine H2 receptor mediating inhibition of arachidonic acid release and activation of cAMP accumulation
72. Protein kinase C activates the MEK-ERK pathway in a manner independent of ras and dependent on raf
73. G(o)-protein α subunits activate mitogen-activated protein kinase via a novel protein kinase C-dependent mechanism
74. Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organelles
75. Microtubule-dependent transport of secretory vesicles visualized in real time with a GFP-tagged secretory protein
76. The interaction between cytoplasmic dynein and dynactin is required for fast axonal transport
77. Visualization of the peroxisomal compartment in living mammalian cells: Dynamic behaviour and association with microtubules
78. 2+ and mitogen-activated protein kinase regulation
79. The phytochrome photoreceptor in the green alga Mesotaenium caldariorium: Implication for a conserved mechanism of phytochrome action
80. The protein kinase C isoforms leading to MAP-kinase activation in CHO cells