A heterotrimeric G protein-phospholipase A2 signaling cascade is involved in the regulation of peroxisomal motility in CHO cells

Journal of Cell Science

Volumn 110, Issue 23, 1997, Pages 2955-2968

  Huber, Christoph M ^a   Saffrich, Rainer ^b   Anton, Markus ^a   Paßreiter, Michael ^a   Ansorge, Wilhelm ^b   Gorgas, Karin ^a   Just, Wilhelm W ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

G protein; Green fluorescent protein; Microtubule; Peroxisomal motility; Phospholipase A2

Indexed keywords

ALUMINUM FLUORIDE; GREEN FLUORESCENT PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); MASTOPARAN; PERTUSSIS TOXIN; PHOSPHOLIPASE A2;

ANIMAL CELL; ARTICLE; CHO CELL; MICROTUBULE; NONHUMAN; PEROXISOME; PRIORITY JOURNAL;

ANIMALS; CALCIUM; CHO CELLS; CRICETINAE; GREEN FLUORESCENT PROTEINS; GTP-BINDING PROTEINS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); KINETICS; LUMINESCENT PROTEINS; MICROBODIES; PHOSPHOLIPASES A; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; TRANSFECTION;

ANIMALIA;

EID: 0031441343     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. 2 activation probably through uncoupling of a GTP-binding protein from the enzyme in rat peritoneal mast cells. Biochem. Pharmacol. 44, 45-50.
2. Allen, R. D., Weiss, D. G., Hayden, J. H., Brown, D. T., Fujiwake, H. and Simpson, M. (1985). Gliding movement of and bidirectional transport along single native microtubules from squid axoplasm: evidence for an active role of microtubules in cytoplasmic transport. J. Cell Biol. 100, 1736-1752.
3. Aniento, F., Emans, N., Griffiths, G. and Gruenberg, J. (1993). Cytoplasmic dynein-dependent vesicular transport from early to late endosomes. J. Cell Biol. 123, 1373-1387.
4. Ercolani, L., Stow, J. L., Boyle, J. F., Holtzman, E. J., Lin, H., Grove, J. R. and Ausiello, D. A. (1990). Membrane localization of the pertussis toxin-sensitive G-protein subunits alpha i-2 and alpha i-3 and expression of a metallothionein-alpha i-2 fusion gene in LLC-PK1 cells. Proc. Nat. Acad. Sci. USA 87, 4635-4639.
5. Fath, K. R. and Lasek, R. J. (1988). Two classes of actin microfilaments are associated with the inner cytoskeleton of axons. J. Cell Biol. 107, 613-621.
6. Fath, K. R., Trimbur, G. M. and Burgess, D. R. (1994). Molecular motors are differentially distributed on Golgi membranes from polarized epithelial cells. J. Cell Biol. 126, 661-675.
7. Forman, D. S., Lynch, K. J. and Smith, R. S. (1987). Organelle dynamics in lobster axons: anterograde, retrograde and stationary mitochondria. Brain Res. 412, 96-106.
8. Gorgas, K. (1984). Peroxisomes in sebaceous glands. V. Complex peroxisomes in the mouse preputial gland: serial sectioning and three-dimensional reconstruction studies. Anat. Embryol. Berl. 169, 261-270.
9. Zaar, K., Hartig, F., Fahimi, H. D. and Gorgas, K. (1984). Peroxisomal aggregates forming large stacks in the lipid segment of the canine kidney. Acta Histochem. Suppl. 29, 165-168.