Discrimination of sepsis and systemic inflammatory response syndrome by determination of circulating plasma concentrations of procalcitonin, protein complement 3a, and interleukin-6

Critical Care Medicine

Volumn 28, Issue 8, 2000, Pages 2793-2798

  Selberg, Oliver ^a   Hecker, Hartmut ^a   Martin, Michael ^a   Klos, Andreas ^a   Bautsch, Wilfried ^a   Köhl, Jörg ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

C reactive protein; Complement 3a; Complement proteins; Elastase; Interleukin 6; Procalcitonin; Sepsis; Systemic inflammatory response syndrome

Indexed keywords

C REACTIVE PROTEIN; COMPLEMENT COMPONENT C3A; CYTOKINE; ELASTASE; INTERLEUKIN 6; PROCALCITONIN;

ADULT; AGED; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; COMPLEMENT ACTIVATION; DISEASE SEVERITY; FEMALE; HUMAN; IMMUNE SYSTEM; INFLAMMATION; INTENSIVE CARE UNIT; MALE; PRIORITY JOURNAL; PROGNOSIS; SEPSIS;

EID: 0033847145     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-200008000-00019     Document Type: Article

References (31)

1. Current understanding of sepsis
2. The complex pattern of cytokines in serum from patients with meningococcal septic shock Association between interleukin 6, interleukin 1, and fatal outcome
3. Association between tumour necrosis factor in serum and fatal outcome in patients with meningococcal disease
4. Increased plasma concentrations of interleukin-6 in sepsis
5. Interleukin-8 in sepsis: Relation to shock and inflammatory mediators
6. Plasma concentrations of the chemokines monocyte chemotactic proteins-1 and -2 are elevated in human sepsis
7. Characterization of complement anaphylatoxins and their biological responses
8. Complement activation in patients with sepsis is in part mediated by C-reactive protein
9. The major acute phase reactants: C-reactive protein, serum amyloid P component and serum amyloid A protein
10. Inflammatory mediators in relation to the development of multiple organ failure in patients after severe blunt trauma
11. Mice lacking neutrophil elastase reveal impaired host defense against Gram negative bacterial sepsis
12. Procalcitonin. A new diagnostic parameter for severe infections and sepsis
13. Procalcitonin - A new indicator for bacterial infections
14. Mortality is increased by procalcitonin and decreased by an antiserum reactive to procalcitonin in experimental sepsis
15. ACCP/ SCCM consensus conference: Definition for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis
16. Re-evaluation of the storage conditions for blood samples which are used for determination of complement activation
17. Rapid quantification of C3a and C5a using a combination of chromatographic and immunoassay procedures
18. Gram-negative sepsis
19. High serum procalcitonin concentrations in patients with sepsis and infection
20. The potential role of procalcitonin and interleukin 8 in the prediction of infected necrosis in acute pancreatitis
21. Pneumonitis-associated hyperprocalcitoninemia
22. Hyperprocalcitonemia in patients with noninfectious SIRS and pulmonary dysfunction associated with cardiopulmonary bypass
23. Plasma cytokine and endotoxin concentrations correlate with survival in patients with the sepsis syndrome
24. Plasma proinflammatory cytokine concentrations, Acute Physiology and Chronic Health Evaluation (APACHE) III scores and survival in patients in an intensive care unit
25. Cytokine profile and correlation to the APACHE III and MPM II scores in patients with sepsis
26. Anaphylatoxins
27. Anaphylatoxin generation in multisystem organ failure
28. Elevated plasma concentrations of the anaphylatoxins C3a and C4a are associated with a fatal outcome in sepsis
29. Complement activation and polymorphonuclear neutrophil leukocyte elastase in sepsis, Correlation with severity of disease
30. Circulating complement proteins in patients with sepsis or systemic inflammatory response syndrome
31. Circulating complement proteins in multiple trauma patients - Correlation with injury severity, development of sepsis, and outcome