Negative ion electrospray high-performance liquid chromatography-mass spectrometry method development for determination of a highly polar phosphonic acid/sulfonic acid compound in plasma. Optimization of ammonium acetate concentration and in-source collision-induced dissociation

Journal of Chromatography B: Biomedical Applications

Volumn 703, Issue 1-2, 1997, Pages 167-175

  Jemal, Mohammed ^a   Almond, Robert ^a   Ouyang, Zheng ^a   Teitz, Deborah ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

BMS 187745; Enzyme inhibitors

Indexed keywords

AMMONIUM ACETATE; BMS 182549; BMS 187745; ENZYME INHIBITOR; PHOSPHONIC ACID DERIVATIVE; SQUALENE SYNTHASE INHIBITOR; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CHOLESTEROL METABOLISM; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HYPERCHOLESTEROLEMIA; MASS SPECTROMETRY; PLASMA; PRIORITY JOURNAL; QUALITY CONTROL; STANDARD;

ACETATES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENZYME INHIBITORS; FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE; HUMANS; MASS SPECTROMETRY; OSMOLAR CONCENTRATION; REGRESSION ANALYSIS; REPRODUCIBILITY OF RESULTS; SULFONIC ACIDS;

EID: 0031451693     PISSN: 15726495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4347(97)00427-1     Document Type: Article

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