Mechanism of glia-neuron cell-fate switch in the Drosophila thoracic neuroblast 6-4 lineage

Development

Volumn 127, Issue 16, 2000, Pages 3513-3522

  Akiyama Oda, Y ^a   Hotta, Y ^a   Tsukita, S ^a   Oda, H ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Asymmetric cell division; Drosophila; Glia; Glial cells missing (gcm); Inscuteable; Miranda; Neuroblast; Neuron; Prospero

Indexed keywords

HOMEODOMAIN PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIVISION; CELL FATE; CELL LINEAGE; CELL NUCLEUS; CONTROLLED STUDY; DROSOPHILA; EMBRYO; GLIA CELL; MUTATION; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NEUROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; STEM CELL; THORAX;

ANIMALS; CELL DIFFERENTIATION; CELL DIVISION; CELL LINEAGE; CYTOSKELETAL PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GREEN FLUORESCENT PROTEINS; LUMINESCENT PROTEINS; MITOSIS; MUTAGENESIS; NERVE TISSUE PROTEINS; NEUROGLIA; NEURONS; NEUROPEPTIDES; NUCLEAR PROTEINS; STEM CELLS; THORACIC NERVES; TRANSCRIPTION FACTORS;

ANIMALIA; HEXAPODA; PROSPERO;

EID: 0033834205     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (58)

1. The gcm-motif: A novel DNA-binding motif conserved in Drosophila and mammals
2. Alteration of cell fate by ectopic expression of Drosophila gilal cells missing in non-neural cells
3. Asymmetric cell division of thoracic neuroblast 6-4 to bifurcate glial and neuronal lineage in Drosophila
4. Distinct mechanisms triggering glial differentiation in Drosophila thoracic and abdominal neuroblasts 6-4
5. Gliogenesis depends on glide/gcm through asymmetric division of neuroglioblasts
6. The embryonic central nervous system lineages of Drosophila melanogaster. I. Neuroblast lineages derived from the ventral half of the neuroectoderm
7. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
8. New neuroblast markers and the origin of the aCC/pCC neurons in the Drosophila central nervous system
9. Staufen-dependent localization of prospero mRNA contributes to neuroblast daughter-cell fate
10. RK2, a glial-specific homeodomain protein required for embryonic nerve cord condensation and viability in Drosophila
11. The prospero gene encodes a divergent homeodomain protein that controls neuronal identity in Drosophila
12. The differentiation of the serotonergic neurons in the Drosophila ventral nerve cord depends on the combined function of the zinc finger proteins Eagle and Huckebein
13. Molecular markers for identified neuroblasts and ganglion mother cells in the Drosophila central nervous system
14. The prospero gene specifies cell fates in the Drosophila central nervous system
15. The Drosophila sanpodo gene controls sibling cell fate and encodes a tropomodulin homolog, an actin/tropomyosin-associated protein
16. Embryonic development of the Drosophila central nervous system
17. The homeobox gene repo is required for the differentiation and maintenance of glia function in the embryonic nervous system of Drosophila melanogaster
18. Eagle, a member of the steroid receptor gene superfamily, is expressed in a subset of neuroblasts and regulates the fate of their putative progeny in the Drosophila CNS
19. Asymmetric segregation of the homeodomain protein Prospero during Drosophila development
20. Glial cells missing: A binary switch between neuronal and glial determination in Drosophila
21. Miranda directs Prospero to a daughter cell during Drosophila asymmetric divisions
22. Distribution, classification, and development of Drosophila glial cells in the late embryonic and early larval ventral nerve cord
23. Lineage, migration, and morphogenesis of longitudinal glia in the Drosophila CNS as revealed by a molecular lineage marker
24. Asymmetric cell division
25. Glial cells missing: A genetic switch that controls glial versus neuronal fate
26. Mechanisms of asymmetric cell division during animal development
27. Asymmetric segregation of Numb and Prospero during cell division
28. Deletion analysis of the Drosophila Inscuteable protein reveals domains for cortical localization and asymmetric localization
29. Inscuteable, a neural precursor gene of Drosophila, encodes a candidate for a cytoskelton adaptor protein
30. Role of inscuteable in orienting asymmetric cell division in Drosophila
31. Inscuteable and Staufen mediate asymmetric localization and segregation of prospero RNA during Drosophila neuroblast cell divisions
32. Cloning of the Drosophila prospero gene and its expression in ganglion mother cells
33. Miranda localizes staufen and prospero asymmetrically in mitotic neuroblasts and epithelial cells in early Drosophila embryogenesis
34. Positive autoregulation of the glial promoting factor glide/gcm
35. Armadillo, bazooka, and stardust are critical for early stages in formation of the zonula adherens and maintenance of the polarized blastoderm epithelium in Drosophila
36. Nonchordate classic cadherins have a structurally and functionally unique domain that is absent from chordate classic cadherins
37. Expression of engrailed proteins in Arthropods, Annelids, and Chordates
38. Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells
39. A stable genomic source of P-element transposase in Drosophila melanogaster
40. Uncoupling cadherin-based adhesion from wingless signalling in Drosophila
41. The embryonic central nervous system linages of Drosophila melanogaster. II. Neuroblast linages derived from the dorsal part of the neuroectoderm
42. Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts
43. The regulator of early gliogenesis glial cells missing is a transcription factor with a novel type of DNA-binding domain
44. Miranda mediates asymmetric protein and RNA localization in the developing nervous system
45. Miranda is required for the asymmetric localization of Prospero during mitosis in Drosophila
46. Miranda as a multidomain adapter linking apically localized Inscuteable and basally localized Staufen and Prospero during asymmetric cell division in Drosophila
47. Sanpodo and Notch act in opposition to Numb to distinguish sibling cell neuron fate in the Drosophila CNS
48. The prospero transcription factor is asymmetrically localized to the cell cortex during neuroblast mitosis in Drosophila
49. Biochemical analysis of Prospero protein during asymmetric cell division: Cortical Prospero is highly phosphorylated relative to nuclear Prospero
50. Staufen, a gene required to localize maternal RNAs in the Drosophila egg
51. A functional analysis of inscuteable and its roles during Drosophila asymmetric cell divisions
52. A common precursor for glia and neurons in the embryonic CNS of Drosophila gives rise to segment-specific lineage variants
53. Numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos
54. Prospero is expressed in neuronal precursors and encodes a nuclear protein that is involved in the control of axonal outgrowth in Drosophila
55. Glide directs glial fate commitment and cell fate switch between neurones and glia
56. Bazooka provides an apical cue for Inscuteable localization in Drosophila neuroblasts
57. Repo encodes a glial-specific homeo domain protein required in the Drosophila nervous system
58. Analysis of partner of inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in Inscuteable apical localization