Alteration of cell fate by ectopic expression of Drosophila glial cells missing in non-neural cells

Development Genes and Evolution

Volumn 208, Issue 10, 1998, Pages 578-585

  Akiyama Oda, Yasuko ^a,b   Hosoya, Toshihiko ^a,c   Hotta, Yoshiki ^a,c  

^a UNIVERSITY OF TOKYO   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF GENETICS   (Japan)

Author keywords

Cell fate determination; Drosophila melanogaster; Ectopic expression; GAL4 UAS system; Glial cells missing

Indexed keywords

CELL ADHESION MOLECULE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; EPIDERMIS CELL; GENE EXPRESSION; GLIA CELL; MESENCHYME CELL; NERVE CELL; NERVOUS SYSTEM; NONHUMAN; PRIORITY JOURNAL; STEM CELL;

ANIMALS; DNA-BINDING PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ECTODERM; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, INSECT; HOMEODOMAIN PROTEINS; HU PARANEOPLASTIC ENCEPHALOMYELITIS ANTIGENS; IMMUNOHISTOCHEMISTRY; INSECT PROTEINS; MESODERM; NEUROGLIA; NEUROPEPTIDES; RIBONUCLEOPROTEINS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 0031797584     PISSN: 0949944X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004270050217     Document Type: Article

References (35)

1. Akiyama Y, Hosoya T, Poole AM, Hotta Y (1996) The gcm-motif: a novel DNA-binding motif conserved in Drosophila and mammals. Proc Natl Acad Sci USA 93: 14912-14916
2. Anderson DJ (1989) The neural crest cell lineage problem: Neuropoiesis? Neuron 3: 1-12
3. Anderson DJ (1995) A molecular switch for the neuron-glia developmental decision. Neuron 15: 1219-1222
4. Bellen HJ, Kooyer S, D'Evelyn D, Pearlman J (1992) The Drosophila couch potato protein is expressed in nuclei of peripheral neuronal precursors and shows homology to RNA-binding proteins. Genes Dev 6: 2125-2136
5. Bernardoni R, Vivancos V, Giangrande A (1997) glide/gcm is expressed and required in the scavenger cell lineage. Dev Biol 191: 118-130
6. Brand AH, Perrimon N (1993) Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118: 401-415
7. Campbell G, Göring H, Lin T, Spana E, Andersson S, Doe CQ, Tomlinson A (1994) RK2, a glial-specific homeodomain protein required for embryonic nerve cord condensation and viability in Drosophila. Development 120: 2957-2966
8. Condron BG, Zinn K (1994) The grasshopper median neuroblast is a multipotent progenitor cell that generate glia and neurons in distinct temporal phases. J Neurosci 14: 5766-5777
9. Doe CQ, Chu-LaGraff Q, Wright DM, Scott MP (1991) The prospero gene specifies cell fates in the Drosophila central nervous system. Cell 65: 451-464
10. Giesen K, Hummel T, Stollewerk A, Harrison S, Travers A, Klämbt C (1997) Glial development in the Drosophila CNS requires concomitant activation of glial and repression of neuronal differentiation genes. Development 124: 2307-2316
11. Greenwald I, Rubin GM (1992) Making a difference: the role of cell-cell interactions in establishing separate identities for equivalent cells. Cell 68: 271-281
12. Greig S, Akam M (1993) Homeotic genes autonomously specify one aspect of pattern in the Drosophila mesoderm. Nature 362: 630-632
13. Gurdon JB (1992) The generation of diversity and pattern in animal development. Cell 68: 185-199
14. Halder G, Callaerts P, Gehring WJ (1995) Induction of ectopic eyes by targeted expression of the eveless gene in Drosophila. Science 267: 1788-1792
15. Halter DA, Urban J, Rickert C, Ner SS, Ito K, Travers AA, Technau GM (1995) The homeobox gene repo is required for the differentiation and maintenance of glia function in the embryonic nervous system of Drosophila melanogaster. Development 121: 317-332
16. Hosoya T, Takizawa K, Nitta K, Hotta Y (1995) glial cells missing: a binary switch between neuronal and glial determination in Drosophila. Cell 82: 1025-1036
17. Ito K, Urban J, Technau GM (1995) Distribution, classification, and development of Drosophila glial cells in the late embryonic and early larval ventral nerve cord. Roux's Arch Dev Biol 204: 284-307
18. Jan YN, Jan LY (1995) Maggot's hair and bug's eye: role of cell interactions and intrinsic factors in cell fate specification. Neuron 14: 1-5
19. Jones BW, Fetter RD, Tear G, Goodman CS (1995) glial cells missing: a genetic switch that controls glial versus neuronal fate. Cell 82: 1013-1023
20. Kiehart DP, Feghali R (1986) Cytoplasmic myosin from Drosophila melanogaster. J Cell Biol 103: 1517-1525
21. Klaes A, Menne T, Stollewerk A, Scholz H, Klämbt C (1994) The Ets transcription factors encoded by the Drosophila gene pointed direct glial cell differentiation in the embryonic CNS. Cell 78: 149-160
22. Klämbt C (1993) The Drosophila gene pointed encodes two ets like proteins, which are involved in the development of the midline glial cells. Development 117: 163-176
23. McConnell SK (1991) The generation of neuronal diversity in the central nervous system. Annu Rev Neurosci 14: 269-300
24. O'Neill EM, Rebay I, Tjian R, Rubin GM (1994) The activities of two Ets-related transcription factors required for Drosophila eye development are modulated by the Ras/MAPK pathway. Cell 78: 137-147
25. Patel NH, Snow PM, Goodman CS (1987) Characterization and cloning of fasciclin III: a glycoprotein expressed on a subset of neurons and axon pathways in Drosophila. Cell 48: 975-988
26. Pfrieger FW, Barres BA (1995) What the fly's glia tell the fly's brain. Cell 83: 671-674
27. Robinow S, Campos AR, Yao KM, White K (1988) The elav gene product of Drosophila, required in neurons, has three RNP consensus motifs. Science 242: 1570-1572
28. Schreiber J, Sock E, Wegner M (1997) The regulator of early gliogenesis glial cells missing is a transcription factor with a novel type of DNA-binding domain. Proc Natl Acad Sci USA 94: 4739-4744
29. Skeath JB, Carroll SB (1992) Regulation of proneural gene expression and cell fate during neuroblast segregation in the Drosophila embryo. Development 114: 939-946
30. Udolph G, Prokop A, Bossing T, Technau GM (1993) A common precursor for glia and neurons in the embryonic CNS of Drosophila gives rise to segment-specific lineage variants. Development 118: 765-775
31. Vincent S, Vonesch JL, Giangrande A (1996) glide directs glial fate commitment and cell fate switch between neurones and glia. Development 122: 131-139
32. Weintraub H, Tapscott SJ, Davis RL, Thayer MJ, Adam MA, Lassar AB, Miller AD (1989) Activation of muscle-specific genes in pigment, nerve, fat, liver, and fibroblast cell lines by forced expression of MyoD. Proc Natl Acad Sci USA 86: 5434-5438
33. Woods DF, Bryant PJ (1993) Apical junctions and cell signalling in epithelia. J Cell Sci [Suppl] 17: 171-181
34. Xiong WC, Okano H, Patel NH, Blendy JA, Montell C (1994) repo encodes a glial-specific homeo domain protein required in the Drosophila nervous system. Genes Dev 8: 981-994
35. Yao KM, White K (1994) Neural specificity of elav expression: defining a Drosophila promoter for directing expression to the nervous system. J Neurochem 63: 41-51