An unusual human IgM antibody with a protruding HCDR3 and high avidity for its peptide ligands

Molecular Immunology

Volumn 37, Issue 6, 2000, Pages 295-310

  Ramsland, Paul A ^a   Shan, Lin ^a   Moomaw, Carolyn R ^b   Slaughter, Clive A ^b   Fan, Zhao Chang ^a   Guddat, Luke W ^c   Edmundson, Allen B ^a  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Antibody structure; Cryoglobulin; Human IgM; Waldenstrom's macroglobulinemia; X ray diffraction

Indexed keywords

CRYOGLOBULIN; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; IMMUNOGLOBULIN M ANTIBODY; LIGAND;

AMINO ACID SEQUENCE; ANTIBODY AFFINITY; ANTIBODY STRUCTURE; ANTIGEN BINDING; ARTICLE; COMPLEMENTARITY DETERMINING REGION; CRYSTAL STRUCTURE; HUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANTIBODY AFFINITY; COMPLEMENTARITY DETERMINING REGIONS; CRYSTALLOGRAPHY, X-RAY; ELECTROSTATICS; HUMANS; IMMUNOGLOBULIN M; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN CONFORMATION; SEQUENCE DELETION; SEQUENCE HOMOLOGY, AMINO ACID; WATER;

EID: 0033832918     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-5890(00)00049-3     Document Type: Article

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