Improved efficiency of gene transfer to the transplanted lung by retrograde vascular gene delivery

Transplant International

Volumn 13, Issue 4, 2000, Pages 241-246

  Jeppsson, Anders ^a   Pellegrini, Carlo ^a   Lee, Ronald ^a   O'Brien, Timothy ^a   Miller, Virginia M ^a   Tazelaar, Henry D ^a   McGregor, C G A ^a  

^a MAYO CLINIC   (United States)

Author keywords

galactosidase; Gene transfer; Lung transplantation

Indexed keywords

BETA GALACTOSIDASE; VIRUS VECTOR;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSDUCTION; GENETIC TRANSFECTION; INFLAMMATION; LUNG ALVEOLUS CELL; LUNG TRANSPLANTATION; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; PULMONARY VEIN; RAT; TRANSGENE;

ADENOVIRIDAE; ANIMALS; BETA-GALACTOSIDASE; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HISTOCYTOCHEMISTRY; INJECTIONS, INTRA-ARTERIAL; INJECTIONS, INTRAVENOUS; LUNG; LUNG TRANSPLANTATION; ORGAN SPECIFICITY; PULMONARY ARTERY; PULMONARY VEINS; RATS; RATS, INBRED LEW; TRANSGENES;

EID: 0033832659     PISSN: 09340874     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001470050697     Document Type: Article

References (18)

1. Distribution of lung preservation solutions in parenchyma and airways: Influence of atelectasis and route of delivery
2. Ex vivo adenoviral-mediated gene transfer to lung isografts during cold preservation
3. Gene therapy in lung transplantation: Feasibility of ex vivo adenovirus-mediated gene transfer to the graft
4. Gene therapy approaches for inherited and acquired lung diseases
5. The Registry of the International Society for Heart and Lung Transplantation: Fourteenth Official Report-1997
6. Gene therapy in lung transplantation: Effective gene transfer via the airways
7. Transbronchial gene transfer of endothelial nitric oxide synthase to transplanted lungs
8. Lung preservation: A review of current practice and future directions
9. In vivo adenovirus-mediated gene transfer to lungs via pulmonary artery
10. Catheter-mediated pulmonary vascular gene transfer and expression
11. In vivo gene delivery to the pulmonary circulation in rats: Transgene distribution and vascular inflammatory response
12. In vivo adenovirus-mediated gene transfer via the pulmonary artery of rats
13. Immune response to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors
14. Early lung allograft function after retrograde and antegrade preservation
15. An approach for treating the hepatobiliary disease of cystic fibrosis by somatic gene transfer
16. Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses
17. Immune response to viral antigens versus transgene product in the elimination of recombinant adenovirus-infected hepatocytes in vivo
18. Immunosuppression prolongs adenoviral mediated transgene expression in cardiac allograft transplantation