Opposite effects of feeding a vitamin A-deficient diet and retinoic acid treatment on brown adipose tissue uncoupling protein 1 (UCP1), UCP2 and leptin expression

Journal of Endocrinology

Volumn 166, Issue 3, 2000, Pages 511-517

  Bonet, M L ^a   Oliver, J ^a   Pico, C ^a   Felipe, F ^a   Ribot, J ^a   Cinti, S ^a   Palou, A ^a  

^a Nutricio I Biotecnologia D   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN; UNCOUPLING PROTEIN 1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; MALE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; RETINOL DEFICIENCY; THERMOGENESIS; VITAMIN SUPPLEMENTATION;

EID: 0033826264     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.0.1660511     Document Type: Article

References (33)

1. A novel regulatory pathway of brown fat thermogenesis. Retinoic acid is a transcriptional activator of the mitochondrial uncoupling protein gene
2. Retinoic acid modulates retinoid X receptor alpha and retinoic acid receptor alpha levels of cultured brown adipocytes
3. Uncoupling protein-3: A new member of the mitochondrial carrier family with tissue-specific expression
4. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
5. Signal transduction in brown adipose tissue recruitment: Noradrenaline and beyond
6. 9-cis retinoic acid induces the expression of the uncoupling protein-2 gene in brown adipocytes
7. In vitro interactions between nuclear proteins and uncoupling protein gene promoter reveal several putative transactivating factors including Ets1, retinoic X receptor, thyroid hormone receptor, and a CACCC box-binding protein
8. Induction of uncoupling protein expression in brown and white adipose tissue by leptin
9. Chronic central leptin infusion enhances insulin-stimulated glucose metabolism and favors the expression of uncoupling proteins
10. Uncoupling protein-2: A novel gene linked to obesity and hyperinsulinemia
11. Leptin and the regulation of body weight in mammals
12. Cloning and characterization of an uncoupling protein homolog: A potential molecular mediator of human thermogenesis
13. Uncoupling protein-3 is a mediator of thermogenesis regulated by thyroid hormone, β3-adrenergic agonists, and leptin
14. Brown adipose tissue thermogenesis: Interdisciplinary studies
15. Mitochondrial uncoupling protein from mouse brown fat
16. In vivo isomerization of retinoic acids. Rapid isomer exchange and gene expression
17. Differential effects of retinoic acid on uncoupling protein-1 and leptin gene expression
18. Dietary vitamin A supplementation in rats: Suppression of leptin and induction of UCP1 mRNA
19. Essential cis-acting elements in rat uncoupling protein gene are in an enhancer containing a complex retinoic acid response domain
20. Molecules in focus: The uncoupling protein thermogenin
21. Evidence for masking of brown adipose tissue mitochondrial GDP-binding sites in response to fasting in rats made obese by dietary manipulation
22. In vitro and in vivo induction of the brown adipocyte uncoupling protein thermogenin by retinoic acid
23. A complex retinoic acid response element in the uncoupling protein gene defines a novel role for retinoids in thermogenesis
24. Retinoids activate proton transport by the uncoupling proteins UCP1 and UCP2
25. Brown adipose tissue response to cafeteria diet-feeding involves induction of the UCP2 gene and is impaired in female rats compared with males
26. Effects of intravenously infused leptin on insulin sensitivity and on the expression of uncoupling proteins in brown adipose tisssue
27. Leptin increases uncoupling protein expression and energy expenditure
28. UCP2, UCP3 and leptin gene expression: Modulation by food restriction and leptin
29. Modulation of uncoupling protein 2 and uncoupling protein 3: Regulation by denervation, leptin and retinoic acid treatment
30. Brown adipose tissue and the regulation of body fat stores
31. Acute cold-induced supression of ob (obese) gene expression in white adipose tissue of mice: Mediation by the sympathetic system
32. UCP3: An uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and adipose tissue
33. Induction by leptin of uncoupling protein-2 and enzymes of fatty acid oxidation