Modification of biophysical properties of lung epithelial Na+ channels by dexamethasone

American Journal of Physiology - Cell Physiology

Volumn 279, Issue 3 48-3, 2000, Pages

  Lazrak, A ^a   Samanta, A ^a   Venetsanou, K ^c   Barbry, P ^d   Matalon, S ^a,b  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c Athens Trauma Hospital   (Greece)

^d CNRS   (France)

Author keywords

A549 cells; Amiloride; ENaC; Lung; Reverse transcription polymerase chain reaction; Single channels; Western blots; Whole cell currents

Indexed keywords

AMILORIDE; DACTINOMYCIN; DEXAMETHASONE; MESSENGER RNA; SODIUM; SODIUM CHANNEL;

ARTICLE; CELL LINE; CONDUCTANCE; CONTROLLED STUDY; GENE EXPRESSION; HOUSEKEEPING GENE; HUMAN; HUMAN CELL; ION TRANSPORT; LUNG ALVEOLUS EPITHELIUM; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SODIUM CURRENT; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

TRIXIS;

EID: 0033825615     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.2000.279.3.c762     Document Type: Article

References (43)

1. + absorption
2. Dexamethasone upregulates the Na-K-ATPase in rat alveolar epithelial cells
3. Epithelial sodium channel related to proteins involved in neurodegeneration
4. + channel is made of three homologous subunits
5. +-ATPase gene regulation by glucocorticoids in a fetal lung epithelial cell line
6. + channel by steroid hormones
7. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
8. The effects of hyperoxia, mechanical ventilation, and dexamethasone on pulmonary antioxidant enzyme activity in the newborn piglet
9. Prophylactic effects of dexamethasone in lung injury caused by hyperoxia and hyperventilation
10. + channel along rat respiratory tract
11. The heterotetrameric architecture of the epithelial sodium channel (ENaC)
12. Early expression of β- and γ-subunits of epithelial sodium channel during human airway development
13. Epithelial sodium channels: Function, structure, and regulation
14. Quantitative RT-PCR assay detecting the transcriptional induction of vascular endothelial growth factor under hypoxia
15. 2+
16. Differential expression of RNA and protein of the three pore-forming subunits of the amiloride-sensitive epithelial sodium channel in taste buds of the rat
17. Gap junction gating sensitivity to physiological internal calcium regardless of pH in Novikoff hepatoma cells
18. Biophysical properties and molecular characterization of amiloride-sensitive sodium channels in A549 cells
19. A continuous tumor-cell line from a human lung carcinoma with properties of type II alveolar epithelial cells
20. Molecular cloning and functional expression of different molecular forms of rat amiloride-binding proteins
21. + channel. A new channel type with homologies to Caenorhabditis elegans degenerins
22. Construction of internal cDNA competitors for measuring IL-10 and IL-12 cytokine gene expression in swine
23. Sodium channels in alveolar epithelial cells: Molecular characterization, biophysical properties, and physiological significance
24. Localization of epithelial sodium channel subunit mRNAs in adult rat lung by in situ hybridization
25. Salt and water transport across alveolar and distal airway epithelia in the adult lung
26. Intact epithelial barrier function is critical for the resolution of alveolar edema in humans
27. Diversity of channels generated by different combinations of epithelial sodium channel subunits
28. Detection of in vivo expression of interleukin-10 using a semi-quantitative polymerase chain reaction method in Schistosoma mansoni infected mice
29. + channel
30. + channel in colon, lung and kidney
31. Epithelial sodium channels
32. Glucocorticoid induction of epithelial sodium channel expression in lung and renal epithelia occurs via trans-activation of a hormone response element in the 5'-flanking region of the human epithelial sodium channel alpha subunit gene
33. Identification of amino acid residues in the alpha, beta, and gamma subunits of the epithelial sodium channel (ENaC) involved in amiloride block and ion permeation
34. Expression and localization of epithelial sodium channel in mammalian urinary bladder
35. Electrophysiological and biochemical evidence that DEG/ENaC cation channels are composed of nine subunits
36. Lung epithelial Na channel subunits are differentially regulated during development and by steroids
37. Differential glucocorticoid regulation of the pulmonary hydrophobic surfactant proteins SP-B and SP-C
38. Glucocorticoid regulation of epithelial sodium channel genes in human fetal lung
39. + channel: From primary structure to function
40. + channel: Biophysical properties, pharmacology, ontogenesis, and molecular cloning
41. Mechanisms and sequelae of increased alveolar fluid clearance in hyperoxic rats
42. Increased expression and activity of sodium channels in alveolar type II cells of hyperoxic rats
43. The amiloride-sensitive epithelial sodium channel alpha-subunit is transcriptionally down-regulated in rat parotid cells by the extracellular signal-regulated protein kinase pathway