Transcriptional regulation of the human FTZ-F1 gene encoding Ad4BP/SF-1

Journal of Biochemistry

Volumn 128, Issue 3, 2000, Pages 517-528

  Oba, K ^a   Yanase, T ^a   Ichino, I ^a   Goto, K ^a   Takayanagi, R ^a   Nawata, H ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Ad4BP SF 1; FTZ F1; Gene regulation

Indexed keywords

STEROIDOGENIC FACTOR 1;

ADRENAL CORTEX CELL; ADRENAL GLAND; ARTICLE; AUTOREGULATION; DNA FLANKING REGION; GENE DELETION; GENE EXPRESSION; GENETIC TRANSCRIPTION; GONAD DEVELOPMENT; HUMAN; PROTEIN EXPRESSION; SITE DIRECTED MUTAGENESIS; STEROIDOGENESIS; TRANSCRIPTION REGULATION;

MAMMALIA;

EID: 0033814698     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a022782     Document Type: Article

References (54)

1. Regulation of the acute production of steroids in steroidogenic cells
2. Molecular biology of steroid hormone synthesis
3. Biochemical diversity of cAMP-dependent transcription of steroid hydroxylase genes in the adrenal cortex
4. FTZ-F1, a steroid hormone receptor-like protein implicated in the activation of Fushi tarazu
5. A common trans-acting factor, Ad4-binding protein, to be the promoters of steroidogenic 450s
6. Steroidogenic factor 1, a key regulator of steroidogenic enzyme expression, is the mouse homolog of fushi tarazu-factor 1
7. Ad4BP regulating steroidogenic P450 gene is a member of steroid hormone receptor superfamily
8. Characterization of the mouse Ftz-F1 gene, which encodes a key regulator of steroid hydroxylase gene expression
9. Steroidogenic factor 1: A key determinant of endocrine development and function
10. Ad4BP/SF-1 regulates cyclic AMP-induced transcription from the proximal promoter (PII) of the human aromatase P450 (CYP19) gene in the ovary
11. Nuclear receptor steroidogenic factor 1 regulates the Mullerian inhibiting substance gene: A link to the sex determination cascade
12. A cell-specific nuclear receptor is essential for adrenal, and gonadal development and sexual differentiation
13. Ad4BP/SF-1, a transcriptional factor essential for the transcription of steroidogenic cytochrome P450 genes and for the establishment of the reproductive function
14. The nuclear receptor steroidogenic factor I acts at multiple levels of the reproductive axis
15. Developmental defectes of the ventromedial hypothalamic nucleus and pituitary gonadotroph in the Ftz-F1 disrupted mice
16. DAX-1 inhibits SF-1 mediated transactivation via a carboxy-terminal domain that is deleted in adrenal hypoplasia congeita
17. DNA binding and transcriptional repression by DAX-1 blocks steroidogenesis
18. Wilms' tumor I and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression
19. An usual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita
20. Mutations in the DAX-1 gene give rise to both X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism
21. Structural characterization of human ad4bp (SF-1) gene
22. Cloning and sequence analysis of the human gene encoding steroidogenic factor 1
23. Embryonal long terminal repeat-binding protein is a murine homolog of FTZ-F1, a member of the steroid receptor superfamily
24. Genomic organization and isoforms of the mouse ELP gene
25. An E box element is required for the expression of the ad4bp gene, a mammalian homologue of ftz-f1 gene, which is essential for adrenal and gonadal development
26. Characterization of the promoter of SF-1, an orphan nuclear receptor required for adrenal and gonadal development
27. Autoregulatory loop in the regulation of the mammalian ftz-f1 gene
28. Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase
29. DNA sequencing with chain-terminating inhibitors
30. pSV00CAT: Low background CAT plasmid
31. Heavy chain variable region contribution to the NPb family of antibodies: Somatic mutation evident in a g2 variable region
32. Activation of CYP11A and CYP11B gene promoters by the steroidogenic cell-specific transcription factor, Ad4BP
33. A one-hour minipreparation technique for extraction of DNA binding proteins for animal tissues
34. Mutations that disrupt DNA binding and dimer formation in the E47 helix-loop-helix protein map to distinct domains
35. The basic helix-loop-helix, leucine zipper transcription factor, USF (upstream stimulatory factor), is a key regulator of SF-1 (steroidogenic factor-1) gene expression in pituitary gonadotrope and steroidogenic cells
36. Molecular cloning and expression of the SF-1/Ad4BP gene in the frog, Rana rugosa
37. Introns in the 3'-untranslated region can inhibit chimeric CAT and beta-galactosidase gene expression
38. The simian virus 40 small-t intron, present in many common expression vectors, leads to aberrant splicing
39. Adrenocortical and gonadal expression of the mammalian Ftz-F1 gene encoding Ad4BP/SF-1 is independent of pituitary control
40. A dosage sensitive locus at chromosome Xp21 is involved in male to female sex reversal
41. Dax-1 antagonizes Sry action in mammalian sex determination
42. Role of Ahch in gonadal development and gametogenesis
43. Identification of a putative steroidogenic factor-1 response element in the DAX-1 promoter
44. Steroidogenic factor-1 and DAX-1 colocalize in multiple cell lineages: Potential links in endocrine development
45. Dax-1 as one of the target genes of Ad4BP/SF-1
46. DAX-1 gene expression upregulated by steroidogenic factor 1 in a adrenocortical carcinoma cell line
47. The murine Dax-1 promoter is stimulated by SF-1 (steroidogenic factor-1) and inhibited by COUP-TP (chicken ovalbumin upstream promoter-transcription factor) via a composite nuclear receptor-regulatory element
48. DAX-1 blocks steroid production at multiple levels
49. Nuclear receptor DAX-1 recruits nuclear receptor corepressor N-CoR to steroidogenic factor 1
50. Interaction of the corepressor Alien with DAX-1 is abrogated by mutations of DAX-1 involved in adrenal hypoplasia congenita
51. Analysis of DNase 1 hypersensitive site of the ELP gene
52. A unified nomenclature system for the nuclear receptor super-family