Aspirin triggered lipid mediators: Novel inhibitors of leucocyte trafficking

Thorax

Volumn 55, Issue SUPPL. 2, 2000, Pages

  Serhan, Charles N ^a   Clish, Clary B ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ARACHIDONIC ACID; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; INTERLEUKIN 1BETA; INTERLEUKIN 4; LIPOXIN A; MACROPHAGE INFLAMMATORY PROTEIN 2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; CELL INFILTRATION; CONFERENCE PAPER; CYTOKINE RELEASE; INFLAMMATION; LEUKOCYTE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; CELL MOVEMENT; CYCLOOXYGENASE INHIBITORS; CYTOKINES; EXUDATES AND TRANSUDATES; HYDROXYEICOSATETRAENOIC ACIDS; LIPID METABOLISM; LIPOXINS; MALE; MICE; MICE, INBRED BALB C; NEUTROPHILS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0033806750     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (17)

1. 1 Vane JR, Bakhle YS, Botting RM. Cyclooxygenases 1 and 2. Annu Rev Pharmacol Toxicol 1998;38:97-120.
2. 2 Marcus AJ. Aspirin as prophylaxis against colorectal cancer. N Engl J Med 1995;333:656-8.
3. 3 Cronstein BN, Montesinos MC, Weissmann G. Salicylates and sulfasalazine, but not glucocorticoids, inhibit leukocyte accumulation by an adenosine-dependent mechanism that is independent of inhibition of prostaglandin synthesis and p105 of NFκB. Proc Natl Acad Sci USA 1999;96:6377-81.
4. 4 Ridker PM, Cushman M, Stampfer MJ,est al. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. N Engl J Med 1997;336:973-9.
5. 5 Levy GN. Prostaglandin H synthases, nonsteroidal antiinflammatory drugs, and colon cancer. FASEB J 1997;11: 234-7.
6. 6 Herschman HR. Recent progress in the cellular and molecular biology of prostaglandin synthesis. Trends Cardiovasc Med 1998;8:145-50.
7. 7 Serhan CN, Haeggström JZ, Leslie CC. Lipid mediator networks in cell signaling: update and impact of cytokines. FASEB J 1996;10:1147-58.
8. 4 stable analogs are potent inhibitors of acute inflammation: evidence for antiinflammatory receptors. J Exp Med 1997;185:1693-704.
9. 9 Clària J, Serhan CN. Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions. Proc Natl Acad Sci USA 1995;92: 9475-9.
10. 4 modulates transmigration of human neutrophils across intestinal epithelial monolayers. J Clin Invest 1993;92:75-82.
11. 11 Serhan CN, Takano T, Gronert K, et al. Lipoxin and aspirin-triggered 15-epi-lipoxin cellular interactions: antiinflammatory lipid mediators. Clin Chem Lab Med 1999;37: 299-309.
12. 12 Serhan CN. Lipoxins and aspirin-triggered 15-epi-lipoxins. In: Gallin JI, Snyderman R, eds. Inflammarion: basic principles and clinical correlates. Philadelphia: Lippincott Williams & Wilkins, 1999: 373-85.
13. 4 inhibit tumor necrosis factor 1α-initiated neutrophil responses and trafficking: regulators of a cytokine-chemokine axis. J Exp Med 1999;189:1923-9.
14. 14 Clish CB, O'Brien JA, Gronert K, et al. Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitment in vivo. Proc Natl Acad Sci USA 1999;96:8247-52.
15. 15 Tessier PA, Naccache PH, Clark-Lewis I, et al. Chemokine networks in vivo: involvement of C-X-C and C-C chemokines in neutrophil extravasation in vivo in response to TNF-α. J Immunol 1997;159:3595-602.
16. 16 Marucha PT, Zeff RA, Kreutzer DL. Cytokine-induced IL-1β gene expression in the human polymorphonuclear leukocyte: transcriptional and post-transcriptional regulation by tumor necrosis factor and IL-1. J Immunol 1991;147:2603-8.
17. 2 production and antileishmanial capacity of human cultured monocytes mediated by IFN-γ. J Immunol 1989;143:3020-4.