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Volumn 29, Issue 3-4, 2000, Pages 295-305

Anti-atherogenic effect of coenzyme Q10 in apolipoprotein E gene knockout mice

Author keywords

Antioxidants; Apolipoprotein E gene knockout mouse; Atherosclerosis; Free radicals; Lipoprotein lipid peroxidation; Ubiquinol; Ubiquinone

Indexed keywords

APOLIPOPROTEIN E; UBIDECARENONE;

EID: 0033805295     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(00)00311-7     Document Type: Article
Times cited : (102)

References (73)
  • 1
    • 0024407363 scopus 로고
    • Beyond cholesterol: Modifications of low-density lipoprotein that increase its atherogenicity
    • Steinberg D., Parthasarathy S., Carew T.E., Khoo J.C., Witztum J.L. Beyond cholesterol modifications of low-density lipoprotein that increase its atherogenicity . N. Engl. J. Med. 320:1989;915-924.
    • (1989) N. Engl. J. Med. , vol.320 , pp. 915-924
    • Steinberg, D.1    Parthasarathy, S.2    Carew, T.E.3    Khoo, J.C.4    Witztum, J.L.5
  • 3
    • 0025106508 scopus 로고
    • Macrophage uptake of cholesterol-containing particles derived from LDL and isolated from atherosclerotic lesions
    • Hoff H.F., O'Neil J., Pepin J.M., Cole T.B. Macrophage uptake of cholesterol-containing particles derived from LDL and isolated from atherosclerotic lesions. Eur. Heart J. 11:(Suppl. E):1990;105-115.
    • (1990) Eur. Heart J. , vol.11 , pp. 105-115
    • Hoff, H.F.1    O'Neil, J.2    Pepin, J.M.3    Cole, T.B.4
  • 4
    • 0026631482 scopus 로고
    • Scavenger receptor-independent stimulation of cholesterol esterification in macrophages by low-density lipoprotein extracted from human aortic intima
    • Steinbrecher U.P., Lougheed M. Scavenger receptor-independent stimulation of cholesterol esterification in macrophages by low-density lipoprotein extracted from human aortic intima. Arterioscler. Thromb. 12:1992;608-625.
    • (1992) Arterioscler. Thromb. , vol.12 , pp. 608-625
    • Steinbrecher, U.P.1    Lougheed, M.2
  • 6
    • 0030979720 scopus 로고    scopus 로고
    • 3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low-density lipoprotein isolated from human atherosclerotic intima
    • Hazen S.L., Heinecke J.W. 3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low-density lipoprotein isolated from human atherosclerotic intima. J. Clin. Invest. 99:1997;2075-2081.
    • (1997) J. Clin. Invest. , vol.99 , pp. 2075-2081
    • Hazen, S.L.1    Heinecke, J.W.2
  • 7
    • 0014788565 scopus 로고
    • The chemical and immunological assay of low-density lipoprotein extracted from human aortic intima
    • Smith E.B., Slater R.S. The chemical and immunological assay of low-density lipoprotein extracted from human aortic intima. Atherosclerosis. 11:1970;417-438.
    • (1970) Atherosclerosis , vol.11 , pp. 417-438
    • Smith, E.B.1    Slater, R.S.2
  • 9
    • 0029129908 scopus 로고
    • Human atherosclerotic plaque contains both oxidized lipids and relatively large amounts of α-tocopherol and ascorbate
    • Suarna C., Dean R.T., May J., Stocker R. Human atherosclerotic plaque contains both oxidized lipids and relatively large amounts of α-tocopherol and ascorbate. Arterioscler. Thromb. Vasc. Biol. 15:1995;1616-1624.
    • (1995) Arterioscler. Thromb. Vasc. Biol. , vol.15 , pp. 1616-1624
    • Suarna, C.1    Dean, R.T.2    May, J.3    Stocker, R.4
  • 10
    • 0033031276 scopus 로고    scopus 로고
    • Coexistence of oxidized lipids and α-tocopherol in all lipoprotein fractions isolated from advanced human atherosclerotic plaques
    • Niu X., Zammit V., Upston J.M., Dean R.T., Stocker R. Coexistence of oxidized lipids and α-tocopherol in all lipoprotein fractions isolated from advanced human atherosclerotic plaques. Arterioscl. Thromb. Vasc. Biol. 19:1999;1708-1718.
    • (1999) Arterioscl. Thromb. Vasc. Biol. , vol.19 , pp. 1708-1718
    • Niu, X.1    Zammit, V.2    Upston, J.M.3    Dean, R.T.4    Stocker, R.5
  • 11
    • 0029883764 scopus 로고    scopus 로고
    • The role of oxidized lipoproteins in atherogenesis
    • Berliner J.A., Heinecke J.W. The role of oxidized lipoproteins in atherogenesis. Free Radic. Biol. Med. 20:1996;707-727.
    • (1996) Free Radic. Biol. Med. , vol.20 , pp. 707-727
    • Berliner, J.A.1    Heinecke, J.W.2
  • 12
    • 0024380694 scopus 로고
    • Proteolytic enzymes of mast cell granules degrade low-density lipoproteins and promote their granule-mediated uptake by macrophages in vitro
    • Kokkonen J.O., Kovanen P.T. Proteolytic enzymes of mast cell granules degrade low-density lipoproteins and promote their granule-mediated uptake by macrophages in vitro. J. Biol. Chem. 264:1989;10749-10755.
    • (1989) J. Biol. Chem. , vol.264 , pp. 10749-10755
    • Kokkonen, J.O.1    Kovanen, P.T.2
  • 13
    • 0032579258 scopus 로고    scopus 로고
    • Secretory sphingomyelinase, a product of the acid sphingomyelinase gene, can hydrolyze atherogenic lipoproteins at neutral pH. Implications for atherosclerotic lesion development
    • Schissel S.L., Jiang X., Tweedie-Hardman J., Jeong T., Camejo E.H., Najib J., Rapp J.H., Williams K.J., Tabas I. Secretory sphingomyelinase, a product of the acid sphingomyelinase gene, can hydrolyze atherogenic lipoproteins at neutral pH. Implications for atherosclerotic lesion development. J. Biol. Chem. 273:1998;2738-2746.
    • (1998) J. Biol. Chem. , vol.273 , pp. 2738-2746
    • Schissel, S.L.1    Jiang, X.2    Tweedie-Hardman, J.3    Jeong, T.4    Camejo, E.H.5    Najib, J.6    Rapp, J.H.7    Williams, K.J.8    Tabas, I.9
  • 14
    • 0026632822 scopus 로고
    • Effect of arterial proteoglycans and glycosaminoglycans on low-density lipoprotein oxidation and its uptake by human macrophages and arterial smooth muscle cells
    • Hurt-Camejo E., Camejo G., Rosengren B., Lopez F., Ahlstrom C., Fager G., Bondjers G. Effect of arterial proteoglycans and glycosaminoglycans on low-density lipoprotein oxidation and its uptake by human macrophages and arterial smooth muscle cells. Arterioscler. Thromb. 12:1992;569-583.
    • (1992) Arterioscler. Thromb. , vol.12 , pp. 569-583
    • Hurt-Camejo, E.1    Camejo, G.2    Rosengren, B.3    Lopez, F.4    Ahlstrom, C.5    Fager, G.6    Bondjers, G.7
  • 16
    • 0024465165 scopus 로고
    • Recognition of oxidized low-density lipoprotein by the scavenger receptor of macrophages results from derivatization of apolipoprotein B by products of fatty acid peroxidation
    • Steinbrecher U.P., Lougheed M., Kwan W.-C., Dirks M. Recognition of oxidized low-density lipoprotein by the scavenger receptor of macrophages results from derivatization of apolipoprotein B by products of fatty acid peroxidation. J. Biol. Chem. 264:1989;15216-15223.
    • (1989) J. Biol. Chem. , vol.264 , pp. 15216-15223
    • Steinbrecher, U.P.1    Lougheed, M.2    Kwan, W.-C.3    Dirks, M.4
  • 17
    • 0033006542 scopus 로고    scopus 로고
    • Tocopherol-mediated peroxidation (TMP) of lipoproteins: Implications for vitamin E as a potential antiatherogenic supplement
    • Upston J.M., Terentis A.C., Stocker R. Tocopherol-mediated peroxidation (TMP) of lipoproteins implications for vitamin E as a potential antiatherogenic supplement . FASEB J. 13:1999;977-994.
    • (1999) FASEB J , vol.13 , pp. 977-994
    • Upston, J.M.1    Terentis, A.C.2    Stocker, R.3
  • 20
    • 0026708232 scopus 로고
    • Low-density lipoprotein is protected from oxidation and the progression of atherosclerosis is slowed in cholesterol-fed rabbits by the antioxidant N,N'-diphenyl-phenylenediamine
    • Sparrow C.P., Doebber T.W., Olszewski J., Wu M.S., Ventre J., Stevens K.A., Chao Y.S. Low-density lipoprotein is protected from oxidation and the progression of atherosclerosis is slowed in cholesterol-fed rabbits by the antioxidant N,N'-diphenyl-phenylenediamine. J. Clin. Invest. 89:1992;1885-1891.
    • (1992) J. Clin. Invest. , vol.89 , pp. 1885-1891
    • Sparrow, C.P.1    Doebber, T.W.2    Olszewski, J.3    Wu, M.S.4    Ventre, J.5    Stevens, K.A.6    Chao, Y.S.7
  • 22
    • 0032893420 scopus 로고    scopus 로고
    • Inhibition by a co-antioxidant of aortic lipoprotein lipid peroxidation and atherosclerosis in apolipoprotein E and low-density lipoprotein receptor gene double knockout mice
    • Witting P.K., Pettersson K., Östlund-Lindqvist A.-M., Westerlund C., Westin Eriksson A., Stocker R. Inhibition by a co-antioxidant of aortic lipoprotein lipid peroxidation and atherosclerosis in apolipoprotein E and low-density lipoprotein receptor gene double knockout mice. FASEB J. 13:1999;667-675.
    • (1999) FASEB J , vol.13 , pp. 667-675
    • Witting, P.K.1    Pettersson, K.2    Östlund-Lindqvist, A.-M.3    Westerlund, C.4    Westin Eriksson, A.5    Stocker, R.6
  • 23
    • 0026081482 scopus 로고
    • Antioxidant activity of probucol and its analogues in hypercholesterolemic Watanabe rabbits
    • Mao S.J., Yates M.T., Rechtin A.E., Jackson R.L., Van-Sickle W.A. Antioxidant activity of probucol and its analogues in hypercholesterolemic Watanabe rabbits. J. Med. Chem. 34:1991;298-302.
    • (1991) J. Med. Chem. , vol.34 , pp. 298-302
    • Mao, S.J.1    Yates, M.T.2    Rechtin, A.E.3    Jackson, R.L.4    Van-Sickle, W.A.5
  • 24
    • 0028341332 scopus 로고
    • A comparison of the anti-atherogenic effects of probucol and a structural analogue of probucol in low-density lipoprotein receptor-deficient rabbits
    • Fruebis J., Steinberg D., Dresel H.A., Carew T.A. A comparison of the anti-atherogenic effects of probucol and a structural analogue of probucol in low-density lipoprotein receptor-deficient rabbits. J. Clin. Invest. 94:1994;392-398.
    • (1994) J. Clin. Invest. , vol.94 , pp. 392-398
    • Fruebis, J.1    Steinberg, D.2    Dresel, H.A.3    Carew, T.A.4
  • 25
    • 0032760071 scopus 로고    scopus 로고
    • Dissociation of atherogenesis from aortic accumulation of lipid hydro(pero)xides in Watanabe heritable hyperlipidemic rabbits
    • Witting P.K., Pettersson K., Östlund-Lindqvist A.-M., Westerlund C., Wågberg M., Stocker R. Dissociation of atherogenesis from aortic accumulation of lipid hydro(pero)xides in Watanabe heritable hyperlipidemic rabbits. J. Clin. Invest. 104:1999;213-220.
    • (1999) J. Clin. Invest. , vol.104 , pp. 213-220
    • Witting, P.K.1    Pettersson, K.2    Östlund-Lindqvist, A.-M.3    Westerlund, C.4    Wågberg, M.5    Stocker, R.6
  • 26
    • 0001511548 scopus 로고
    • The function of coenzyme Q in free radical production and as an antioxidant: A review
    • Beyer R.E., Nordenbrand K., Ernster L. The function of coenzyme Q in free radical production and as an antioxidant a review . Chem. Scripta. 27:1987;145-153.
    • (1987) Chem. Scripta , vol.27 , pp. 145-153
    • Beyer, R.E.1    Nordenbrand, K.2    Ernster, L.3
  • 27
    • 0033038638 scopus 로고    scopus 로고
    • A role for reduced coenzyme Q in atherosclerosis?
    • Thomas S.R., Witting P.K., Stocker R. A role for reduced coenzyme Q in atherosclerosis? BioFactors. 9:1999;207-224.
    • (1999) BioFactors , vol.9 , pp. 207-224
    • Thomas, S.R.1    Witting, P.K.2    Stocker, R.3
  • 28
    • 0025979077 scopus 로고
    • Ubiquinol-10 protects human low-density lipoprotein more efficiently against lipid peroxidation than does α-tocopherol
    • Stocker R., Bowry V.W., Frei B. Ubiquinol-10 protects human low-density lipoprotein more efficiently against lipid peroxidation than does α-tocopherol. Proc. Natl. Acad. Sci. USA. 88:1991;1646-1650.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 1646-1650
    • Stocker, R.1    Bowry, V.W.2    Frei, B.3
  • 29
    • 0025327523 scopus 로고
    • Ubiquinol-10 is an effective lipid-soluble antioxidant at physiological concentrations
    • Frei B., Kim M., Ames B.N. Ubiquinol-10 is an effective lipid-soluble antioxidant at physiological concentrations. Proc. Natl. Acad. Sci. USA. 87:1990;4879-4883.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 4879-4883
    • Frei, B.1    Kim, M.2    Ames, B.N.3
  • 31
    • 0025358550 scopus 로고
    • Stopped-flow kinetic study of the regeneration reaction of tocopheroxyl radical by reduced ubiquinone-10 in solution
    • Mukai K., Kikuchi S., Urano S. Stopped-flow kinetic study of the regeneration reaction of tocopheroxyl radical by reduced ubiquinone-10 in solution. Biochim. Biophys. Acta. 1035:1990;77-82.
    • (1990) Biochim. Biophys. Acta , vol.1035 , pp. 77-82
    • Mukai, K.1    Kikuchi, S.2    Urano, S.3
  • 32
    • 0025369150 scopus 로고
    • Antioxidant effects of ubiquinones in microsomes and mitochondria are mediated by tocopherol recycling
    • Kagan V., Serbinova E., Packer L. Antioxidant effects of ubiquinones in microsomes and mitochondria are mediated by tocopherol recycling. Biochem. Biophys. Res. Commun. 169:1990;851-857.
    • (1990) Biochem. Biophys. Res. Commun. , vol.169 , pp. 851-857
    • Kagan, V.1    Serbinova, E.2    Packer, L.3
  • 33
    • 0027213625 scopus 로고
    • Tocopherol-mediated peroxidation. The pro-oxidant effect of vitamin E on the radical-initiated oxidation of human low-density lipoprotein
    • Bowry V.W., Stocker R. Tocopherol-mediated peroxidation. The pro-oxidant effect of vitamin E on the radical-initiated oxidation of human low-density lipoprotein. J. Am. Chem. Soc. 115:1993;6029-6044.
    • (1993) J. Am. Chem. Soc. , vol.115 , pp. 6029-6044
    • Bowry, V.W.1    Stocker, R.2
  • 34
    • 0026734786 scopus 로고
    • Dietary supplementation with coenzyme Q10 results in increased levels of ubiquinol-10 within circulating lipoproteins and increased resistance of human low-density lipoprotein to the initiation of lipid peroxidation
    • Mohr D., Bowry V.W., Stocker R. Dietary supplementation with coenzyme Q10 results in increased levels of ubiquinol-10 within circulating lipoproteins and increased resistance of human low-density lipoprotein to the initiation of lipid peroxidation. Biochim. Biophys. Acta. 1126:1992;247-254.
    • (1992) Biochim. Biophys. Acta , vol.1126 , pp. 247-254
    • Mohr, D.1    Bowry, V.W.2    Stocker, R.3
  • 35
    • 0032770261 scopus 로고    scopus 로고
    • Antioxidant defenses in rat intestine and mesenteric lymph
    • Mohr D., Umeda Y., Redgrave T.G., Stocker R. Antioxidant defenses in rat intestine and mesenteric lymph. Redox Report. 4:1999;79-87.
    • (1999) Redox Report , vol.4 , pp. 79-87
    • Mohr, D.1    Umeda, Y.2    Redgrave, T.G.3    Stocker, R.4
  • 36
    • 0028198105 scopus 로고
    • ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titres of autoantibodies to malondialdehyde-lysine in serum
    • Palinski W., Ord V.A., Plump A.S., Breslow J.L., Steinberg D., Witztum J.L. ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titres of autoantibodies to malondialdehyde-lysine in serum. Arterioscler. Thromb. 14:1994;605-616.
    • (1994) Arterioscler. Thromb. , vol.14 , pp. 605-616
    • Palinski, W.1    Ord, V.A.2    Plump, A.S.3    Breslow, J.L.4    Steinberg, D.5    Witztum, J.L.6
  • 37
    • 0028059454 scopus 로고
    • Increased plasma and lipoprotein lipid peroxidation in apoE-deficient mice
    • Hayek T., Oiknine J., Brook J.G., Aviram M. Increased plasma and lipoprotein lipid peroxidation in apoE-deficient mice. Biochem. Biophys. Res. Commun. 201:1994;1567-1574.
    • (1994) Biochem. Biophys. Res. Commun. , vol.201 , pp. 1567-1574
    • Hayek, T.1    Oiknine, J.2    Brook, J.G.3    Aviram, M.4
  • 40
    • 0023479189 scopus 로고
    • Detection of lipid hydroperoxides and hydrogen peroxide at picomole levels by an HPLC and isoluminol chemiluminescence assay
    • Yamamoto Y., Ames B.N. Detection of lipid hydroperoxides and hydrogen peroxide at picomole levels by an HPLC and isoluminol chemiluminescence assay. Free Radic. Biol. Med. 3:1987;359-361.
    • (1987) Free Radic. Biol. Med. , vol.3 , pp. 359-361
    • Yamamoto, Y.1    Ames, B.N.2
  • 41
    • 0025127627 scopus 로고
    • Use of ascorbate as test for catalytic metals in simple buffers
    • Buettner G.R. Use of ascorbate as test for catalytic metals in simple buffers. Methods Enzymol. 186:1990;125-127.
    • (1990) Methods Enzymol , vol.186 , pp. 125-127
    • Buettner, G.R.1
  • 42
    • 0026536066 scopus 로고
    • Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells
    • Piedrahita J.A., Zhang S.H., Hagaman J.R., Oliver P.M., Maeda N. Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells. Proc. Natl. Acad. Sci. USA. 89:1992;4471-4475.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 4471-4475
    • Piedrahita, J.A.1    Zhang, S.H.2    Hagaman, J.R.3    Oliver, P.M.4    Maeda, N.5
  • 43
    • 0031762781 scopus 로고    scopus 로고
    • Assessment of pro- And antioxidant activity of vitamin E in human low-density lipoprotein and plasma
    • Witting P.K., Mohr D., Stocker R. Assessment of pro- and antioxidant activity of vitamin E in human low-density lipoprotein and plasma. Methods Enzymol. 299:1998;362-375.
    • (1998) Methods Enzymol , vol.299 , pp. 362-375
    • Witting, P.K.1    Mohr, D.2    Stocker, R.3
  • 44
    • 0029878284 scopus 로고    scopus 로고
    • Cosupplementation with coenzyme Q prevents the pro-oxidant effect of α-tocopherol and increases the resistance of low-density lipoprotein towards transition metal-dependent oxidation initiation
    • Thomas S.R., Neuzil J., Stocker R. Cosupplementation with coenzyme Q prevents the pro-oxidant effect of α-tocopherol and increases the resistance of low-density lipoprotein towards transition metal-dependent oxidation initiation. Arterioscl. Thromb. Vasc. Biol. 16:1996;687-696.
    • (1996) Arterioscl. Thromb. Vasc. Biol. , vol.16 , pp. 687-696
    • Thomas, S.R.1    Neuzil, J.2    Stocker, R.3
  • 45
    • 0030641128 scopus 로고    scopus 로고
    • Requirement for, promotion, or inhibition by α-tocopherol of radical-induced initiation of plasma lipoprotein lipid peroxidation
    • Neuzil J., Thomas S.R., Stocker R. Requirement for, promotion, or inhibition by α-tocopherol of radical-induced initiation of plasma lipoprotein lipid peroxidation. Free Radic. Biol. Med. 22:1997;57-71.
    • (1997) Free Radic. Biol. Med. , vol.22 , pp. 57-71
    • Neuzil, J.1    Thomas, S.R.2    Stocker, R.3
  • 46
    • 0028239166 scopus 로고
    • Rapid isolation of lipoproteins and assessment of their peroxidation by HPLC postcolumn chemiluminescence
    • Sattler W., Mohr D., Stocker R. Rapid isolation of lipoproteins and assessment of their peroxidation by HPLC postcolumn chemiluminescence. Methods Enzymol. 233:1994;469-489.
    • (1994) Methods Enzymol , vol.233 , pp. 469-489
    • Sattler, W.1    Mohr, D.2    Stocker, R.3
  • 47
    • 0031887228 scopus 로고    scopus 로고
    • Radical-induced lipoprotein and plasma lipid oxidation in normal and apolipoprotein E gene knockout (apoE-/-) mice. ApoE-/- mouse as a model for testing the role of tocopherol-mediated peroxidation in atherogenesis
    • Neuzil J., Christison J.K., Iheanacho E., Fragonas J.-C., Zammit V., Hunt N.H., Stocker R. Radical-induced lipoprotein and plasma lipid oxidation in normal and apolipoprotein E gene knockout (apoE-/-) mice. ApoE-/- mouse as a model for testing the role of tocopherol-mediated peroxidation in atherogenesis. J. Lipid Res. 39:1998;354-368.
    • (1998) J. Lipid Res. , vol.39 , pp. 354-368
    • Neuzil, J.1    Christison, J.K.2    Iheanacho, E.3    Fragonas, J.-C.4    Zammit, V.5    Hunt, N.H.6    Stocker, R.7
  • 48
    • 0024241234 scopus 로고
    • Evaluation of an isoluminol chemiluminescence assay for the detection of hydroperoxides in human blood plasma
    • Frei B., Yamamoto Y., Niclas D., Ames B.N. Evaluation of an isoluminol chemiluminescence assay for the detection of hydroperoxides in human blood plasma. Anal. Biochem. 175:1988;120-130.
    • (1988) Anal. Biochem. , vol.175 , pp. 120-130
    • Frei, B.1    Yamamoto, Y.2    Niclas, D.3    Ames, B.N.4
  • 49
    • 33845470074 scopus 로고
    • Autoxidation of micelles and model membranes. Quantitative kinetic measurements can be made by using either water-soluble or lipid-soluble initiators with water-soluble or lipid-soluble chain-breaking antioxidants
    • Barclay L.R.C., Locke S.J., MacNeil J.M., VanKessel J. Autoxidation of micelles and model membranes. Quantitative kinetic measurements can be made by using either water-soluble or lipid-soluble initiators with water-soluble or lipid-soluble chain-breaking antioxidants. J. Am. Chem. Soc. 106:1984;2479-2481.
    • (1984) J. Am. Chem. Soc. , vol.106 , pp. 2479-2481
    • Barclay, L.R.C.1    Locke, S.J.2    MacNeil, J.M.3    Vankessel, J.4
  • 50
    • 2642608661 scopus 로고    scopus 로고
    • Reduction of atherosclerosis in mice by inhibition of CD40 signalling
    • Mach F., Schonbeck U., Sukhova G.K., Atkinson E., Libby P. Reduction of atherosclerosis in mice by inhibition of CD40 signalling. Nature. 394:1998;200-203.
    • (1998) Nature , vol.394 , pp. 200-203
    • Mach, F.1    Schonbeck, U.2    Sukhova, G.K.3    Atkinson, E.4    Libby, P.5
  • 51
    • 0024448078 scopus 로고
    • Discharge of newly synthesized dolichol and ubiquinone with lipoproteins to rat liver perfusate and to the bile
    • Elmberger P.G., Kalén A., Brunk U.T., Dallner G. Discharge of newly synthesized dolichol and ubiquinone with lipoproteins to rat liver perfusate and to the bile. Lipids. 24:1989;919-930.
    • (1989) Lipids , vol.24 , pp. 919-930
    • Elmberger, P.G.1    Kalén, A.2    Brunk, U.T.3    Dallner, G.4
  • 53
    • 0032587816 scopus 로고    scopus 로고
    • Effects of coenzyme Q10 and α-tocopherol administration on their tissue levels in the mouse: Elevation of mitochondrial α-tocopherol by coenzyme Q10
    • Lass A., Forster M.J., Sohal R.S. Effects of coenzyme Q10 and α-tocopherol administration on their tissue levels in the mouse elevation of mitochondrial α-tocopherol by coenzyme Q10 . Free Radic. Biol. Med. 26:1999;1375-1382.
    • (1999) Free Radic. Biol. Med. , vol.26 , pp. 1375-1382
    • Lass, A.1    Forster, M.J.2    Sohal, R.S.3
  • 54
    • 0027958084 scopus 로고
    • ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree
    • Nakashima Y., Plump A.S., Raines E.W., Breslow J.L., Ross R. ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree. Arterioscler. Thromb. 14:1994;133-140.
    • (1994) Arterioscler. Thromb. , vol.14 , pp. 133-140
    • Nakashima, Y.1    Plump, A.S.2    Raines, E.W.3    Breslow, J.L.4    Ross, R.5
  • 56
    • 0028230972 scopus 로고
    • Radical-mediated oxidation of isolated human very low-density lipoprotein
    • Mohr D., Stocker R. Radical-mediated oxidation of isolated human very low-density lipoprotein. Arterioscl. Thromb. 14:1994;1186-1192.
    • (1994) Arterioscl. Thromb. , vol.14 , pp. 1186-1192
    • Mohr, D.1    Stocker, R.2
  • 58
    • 0032487487 scopus 로고    scopus 로고
    • Oxidants and antioxidants in the pathogenesis of atherosclerosis: Implications for the oxidized low-density lipoprotein hypothesis
    • Heinecke J.W. Oxidants and antioxidants in the pathogenesis of atherosclerosis implications for the oxidized low-density lipoprotein hypothesis . Atherosclerosis. 141:1998;1-15.
    • (1998) Atherosclerosis , vol.141 , pp. 1-15
    • Heinecke, J.W.1
  • 60
    • 0026044283 scopus 로고
    • Reactivity of phospholipid hydroperoxide glutathione peroxidase with membrane and lipoprotein lipid hydroperoxides
    • Maiorino M., Thomas J.P., Girotti A.W., Ursini F. Reactivity of phospholipid hydroperoxide glutathione peroxidase with membrane and lipoprotein lipid hydroperoxides. Free Radic. Res. Commun. 12-13:1991;131-135.
    • (1991) Free Radic. Res. Commun. , vol.1213 , pp. 131-135
    • Maiorino, M.1    Thomas, J.P.2    Girotti, A.W.3    Ursini, F.4
  • 61
    • 0028901456 scopus 로고
    • Cholesterylester hydroperoxide-reducing activity associated with isolated high- And low-density lipoproteins
    • Sattler W., Christison J.K., Stocker R. Cholesterylester hydroperoxide-reducing activity associated with isolated high- and low-density lipoproteins. Free Radic. Biol. Med. 18:1995;421-429.
    • (1995) Free Radic. Biol. Med. , vol.18 , pp. 421-429
    • Sattler, W.1    Christison, J.K.2    Stocker, R.3
  • 62
    • 0032513108 scopus 로고    scopus 로고
    • Oxidation of high-density lipoproteins. II. Evidence for direct reduction of HDL lipid hydroperoxides by methionine residues of apolipoproteins AI and AII
    • Garner B., Waldeck A.R., Witting P.K., Rye K.-A., Stocker R. Oxidation of high-density lipoproteins. II. Evidence for direct reduction of HDL lipid hydroperoxides by methionine residues of apolipoproteins AI and AII. J. Biol. Chem. 273:1998;6088-6095.
    • (1998) J. Biol. Chem. , vol.273 , pp. 6088-6095
    • Garner, B.1    Waldeck, A.R.2    Witting, P.K.3    Rye, K.-A.4    Stocker, R.5
  • 63
    • 0031863735 scopus 로고    scopus 로고
    • Reduction of phosphatidylcholine hydroperoxide by apolipoprotein A-I: Purification of the hydroperoxide-reducing proteins from human blood plasma
    • Mashima R., Yamamoto Y., Yoshimura S. Reduction of phosphatidylcholine hydroperoxide by apolipoprotein A-I purification of the hydroperoxide-reducing proteins from human blood plasma . J. Lipid Res. 39:1998;1133-1140.
    • (1998) J. Lipid Res. , vol.39 , pp. 1133-1140
    • Mashima, R.1    Yamamoto, Y.2    Yoshimura, S.3
  • 64
    • 0025084538 scopus 로고
    • Oxygenation of biological membranes by the pure reticulocyte lipoxygenase
    • Kuhn H., Belkner J., Wiesner R., Brash A.R. Oxygenation of biological membranes by the pure reticulocyte lipoxygenase. J. Biol. Chem. 265:1990;18351-18361.
    • (1990) J. Biol. Chem. , vol.265 , pp. 18351-18361
    • Kuhn, H.1    Belkner, J.2    Wiesner, R.3    Brash, A.R.4
  • 65
    • 0031752607 scopus 로고    scopus 로고
    • Vitamin E suppresses isoprostane generation in vivo and reduces atherosclerosis in apoE-deficient mice
    • Pratico D., Tangirala R.K., Radar D., Rokach J., FitzGerald G.A. Vitamin E suppresses isoprostane generation in vivo and reduces atherosclerosis in apoE-deficient mice. Nature Med. 4:1998;1189-1192.
    • (1998) Nature Med , vol.4 , pp. 1189-1192
    • Pratico, D.1    Tangirala, R.K.2    Radar, D.3    Rokach, J.4    Fitzgerald, G.A.5
  • 67
    • 0031829432 scopus 로고    scopus 로고
    • Control of arterial tone after long-term coenzyme Q10 supplementation in senescent rats
    • Lonnrot K., Porsti I., Alho H., Wu X., Hervonen A., Tolvanen J.P. Control of arterial tone after long-term coenzyme Q10 supplementation in senescent rats. Br. J. Pharmacol. 124:1998;1500-1506.
    • (1998) Br. J. Pharmacol. , vol.124 , pp. 1500-1506
    • Lonnrot, K.1    Porsti, I.2    Alho, H.3    Wu, X.4    Hervonen, A.5    Tolvanen, J.P.6
  • 69
    • 0032189338 scopus 로고    scopus 로고
    • Acute administration of liposomal coenzyme Q10 increases myocardial tissue levels and improves tolerance to ischemia reperfusion injury
    • Niibori K., Yokoyama H., Crestanello J.A., Whitman G.J. Acute administration of liposomal coenzyme Q10 increases myocardial tissue levels and improves tolerance to ischemia reperfusion injury. J. Surg. Res. 79:1998;141-145.
    • (1998) J. Surg. Res. , vol.79 , pp. 141-145
    • Niibori, K.1    Yokoyama, H.2    Crestanello, J.A.3    Whitman, G.J.4
  • 71
    • 0028455370 scopus 로고
    • Coenzyme Q10 enhances cardiac functional and metabolic recovery and reduces Ca2+ overload during postischemic reperfusion
    • Hano O., Thompson Gorman S.L., Zweier J.L., Lakatta E.G. Coenzyme Q10 enhances cardiac functional and metabolic recovery and reduces Ca2+ overload during postischemic reperfusion. Am. J. Physiol. 266:1994;H2174-H2181.
    • (1994) Am. J. Physiol. , vol.266 , pp. 2174-H2181
    • Hano, O.1    Thompson Gorman, S.L.2    Zweier, J.L.3    Lakatta, E.G.4
  • 72
    • 0032588768 scopus 로고    scopus 로고
    • Overview of the use of CoQ10 in cardiovascular disease
    • Langsjoen P.H., Langsjoen A.M. Overview of the use of CoQ10 in cardiovascular disease. Biofactors. 9:1999;273-284.
    • (1999) Biofactors , vol.9 , pp. 273-284
    • Langsjoen, P.H.1    Langsjoen, A.M.2


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