Acute administration of liposomal coenzyme Q10 increases myocardial tissue levels and improves tolerance to ischemia reperfusion injury

Journal of Surgical Research

Volumn 79, Issue 2, 1998, Pages 141-145

  Niibori, Koki ^a   Yokoyama, Hitoshi ^a   Crestanello, Juan A ^a   Whitman, Glenn J R ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Coenzyme Q10; Ischemia; Liposome; Reperfusion injury; Tissue level

Indexed keywords

CREATINE KINASE; LIPOSOME; OXYGEN; UBIDECARENONE; UBIQUINONE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; HEART MUSCLE; HEART MUSCLE ISCHEMIA; HEART MUSCLE OXYGEN CONSUMPTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; TISSUE LEVEL;

EID: 0032189338     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsre.1998.5411     Document Type: Article

References (28)

1. Kukreja R. C., Hess M. L. The oxygen free radical system: From equations through membrane-protein interactions to cardiovascular injury and protection. Cardivasc. Res. 26:1992;641.
2. Lenaz G., Fato R., Castelluccio C., Genova M. L., Bovina C., Estornell E., Valls V., Pallotti C. G. The functions of coenzyme Q in the mitochondria. Clin. Invest. 71:1993;66.
3. Mitchell P. The vital protonmotive role of coenzyme Q. Biomedical and Clinical Aspects of CoQ. 1991;Elseviers, Amsterdam. p. 3-10.
4. Lenaz G., Battino M., Castelluccio C., Fato R., Cavazzoni M., Rauchova H., Bovina C., Formiggini G., Parenti C. G. Studies of the role of ubiquinone in the control of the mitochondrial respiratory chain. Free. Rad. Res. Commun. 8:1990;317.
5. Battino M., Fato R., Parenti-Castelli G., Lenaz G. Coenzyme Q can control the efficiency of oxidative phosphorylation. Int. J. Tissue Reac. 12:1990;137.
6. Crane F. L., Sun I. L., Sun E. E. The essential function of coenzyme Q. Clin. Invest. 71:1993;S55.
7. Ernster L., Forsmark P. Ubiquinol: An endogenous antioxidant in aerobic organisms. Clin. Invest. 71:1993;60.
8. Crestanello J. A., Kamelgard J., Lingle D. M., Mortensen S. A., Rhode M., Whitman G. J. R. Elucidation of a tripartite mechanism underlying the improvement in cardiac tolerance to ischemia by coenzyme Q10 pretreatment. J. Thorac. Cardiovasc. Surg. 111:1996;443.
9. Tanaka J., Tominaga R., Yoshitoshi M., Matsui K., Komori M., Sese A., Yasui H., Tokunaga K. Coenzyme Q10: The prophylactic effect on low cardiac output following cardiac valve replacement. Ann. Thorac. Surg. 33:1982;145.
10. 10. J. Thorac. Cardiovasc. Surg. 107:1994;242.
11. Katayama K., Takada M., Yuzuriha T., Abe K., Ikenoya S. Simultaneous determination of ubiquinone-10 and ubiquinol-10 in tissue and mitochondria by high liquid chromatography. Biochem. Biophys. Res. Commun. 95:1980;971.
12. Ernster L., Dallner G. Biochemical, phisiological and madical aspects of ubiquinone function. Biochem. Biophys. Acta. 1271:1995;195.
13. Forsmark-Andrée P., Ernster L. Evidence for a protective effect of endogenous ubiquinol against oxidative damage to mitochondria protein and DNA during lipid peroxidation. Mol. Asp. Med. 15:1994;s73.
14. Zhang Y., Aberg F., Appelkvist E. L., Dallner G., Ernster L. Uptake of dietary coenzyme Q supplement is limited in rats. J. Nutr. 125:1995;446.
15. Alessandri M. G., Scalori V., Giovannini L., Mian M., Bertelli A. A. E. Plasma and tissue concentrations of coenzyme Q10 in the rat after intravenous administration by a microsphere delivery system or in a new type of solution. Int. J. Tissue Reac. X:1988;99.
16. 10. Biochem. Biophys. Acta. 759:1983;286.
17. Banerjee A., Grosso M. A., Brown J., Rogers K., Whitman G. J. Oxygen metabolite effects on creatine kinase and cardiac energetics after reperfusion. Am. J. Physiol. 261:1991;H590.
18. Dean E. N., Shlafer M., Nicklas J. M. The oxygen consumption paradox of stunned myocardium in dogs. Basic Res. Cardiol. 85:1990;120.
19. Piper H., Noll T., Siegmund B. Mitochondrial function in the oxygen depleted and reoxygenated myocardial cell. Cardiovasc. Res. 28:1994;1.
20. Flameng W., Andres J., Ferdinande P., Mattheussen M., Van Belle H. Mitochondrial function in myocardial stunning. J. Mol. Cell. Cardiol. 23:1991;1.
21. Asimakis G. K., Zwischenberger J. B., Inners-McBride K., Sordahl L. A., Conti V. R. Postischemic recovery of mitochondrial adenine nucleotides in the heart. Circulation. 85:1992;2212.
22. Bolling S., Olszanski B., Childs K., Gallagher K., Ning X. Stunning, preconditioning, and functional recovery after global myocardial ischemia. Ann. Thorac. Surg. 58:1994;822.
23. Murry C. E. A mechanism of myocardial stunning. Circulation. 82:1990;723.
24. Poole-Wilson P., Holmberg S., Williams A. A possible molecular mechanism for stunning of the myocardium. Eur. Heart. J. 12:1991;25.
25. Braunwald E. Stunning of the myocardium: An update. Cardiovasc. Drugs Ther. 5:1991;849.
26. Ambrosio G., Jacobus W. E., Mitchell M. C., Litt M. R., Becker L. C. Effects of ATP precursors and free ADP content and functional recovery of postischemic hearts. Am. J. Physiol. 256:1989;H560.
27. Auchampach J. A., Maruyama M., Cavero I., Gross G. J. Pharmacological evidence for a role of ATP-dependent potassium channels in myocardial stunning. Circulation. 86:1992;311.
28. Suntres Z. E., Shek P. N. Treatment of LPS-induced tissue injury: Role of liposomal antioxidants. Shock. 6:1996;s57.