Protein phosphatase type-1 regulatory subunits Reg1p and Reg2p act as signal transducers in the glucose-induced inactivation of maltose permease in Saccharomyces cerevisiae

Molecular and General Genetics

Volumn 263, Issue 3, 2000, Pages 411-422

  Jiang, H ^a   Tatchell, K ^b   Liu, S ^a   Michels, C A ^a  

^a CITY UNIVERSITY OF NEW YORK   (United States)

^b LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

Glucose signaling; Maltose permease; REG1,2; Yeast

Indexed keywords

GENE PRODUCT; GLUCOSE; MALTOSE; MALTOSE PERMEASE; PERMEASE; PHOSPHOPROTEIN PHOSPHATASE 1; REG1P PROTEIN; REG2P PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CARBOHYDRATE TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME SUBSTRATE; ENZYME SUBUNIT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION;

ALPHA-GLUCOSIDASES; BLOTTING, WESTERN; CELL CYCLE; ENZYME ACTIVATION; FLOW CYTOMETRY; FUNGAL PROTEINS; GENOTYPE; GLUCOSE; KINETICS; MALTOSE; MEMBRANE TRANSPORT PROTEINS; MODELS, BIOLOGICAL; PHENOTYPE; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; SUPPORT, U.S. GOV'T, P.H.S.; TIME FACTORS;

SACCHAROMYCES CEREVISIAE;

EID: 0033794796     PISSN: 00268925     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004380051185     Document Type: Article

References (30)

1. SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box
2. Alanine-scanning mutagenesis of protein phosphatase type 1 in the yeast Saccharomyces cerevisiae
3. G1 cyclin turnover and nutrient uptake are controlled by a common pathway in yeast
4. A regulated MET3-GLC7 gene fusion provides evidence of a mitotic role for Saccharomyces cerevisiae
5. MAL11 and MAL61 encode the inducible high-affinity maltose transporter of Saccharomyces cerevisiae
6. Identification of the structural gene encoding maltase within the MAL6 locus of Saccharomyces carlsbergensis
7. A family of versatile centromeric vectors designed for use in the sectoring-shuffle mutagenesis assay in Saccharomyces cerevisiae
8. A defect in carbon catabolite repression associated with uncontrollable and excessive maltose uptake
9. Misregulation of maltose uptake in a glucose repression defective mutant of Saccharomyces cerevisiae leads to glucose poisoning
10. Suppressors reveal two classes of glucose repression in the yeast Saccharomyces cerevisiae
11. The REG2 gene of Saccharomyces cerevisiae encodes a type 1 protein phosphatase-binding protein that functions with Reg1p and the Snf1 protein kinase to regulate growth
12. Constitutive mutations of the Saccharomyces cerevisiae MAL-activator genes MAL23, MAL43, MAL63, and mal64
13. A family of cyclin homologs that control the G1 phase in yeast
14. The Glc7 type 1 protein phosphatase of Saccharomyces cerevisiae is required for cell cycle progression in G2/M
15. The EGP1 gene may be a positive regulator of protein phosphatase type 1 in the growth control of Saccharomyces cerevisiae
16. Eliminating all obstacles: Regulated proteolysis in the eukaryotic cell cycle
17. Analysis of the mechanism by which glucose inhibits maltose induction of MAL gene expression in Saccharomyces
18. Genetic interactions between REG1/HEX2 and GLC7, the gene encoding the protein phosphatase type 1 catalytic subunit in Saccharomyces cerevisiae
19. Two glucose sensing/signaling pathways stimulate glucose-induced inactivation of maltose permease in Saccharomyces
20. Metabolic signals trigger glucose-induced inactivation of maltose permease in Saccharomyces
21. Feasting, fasting, and fermenting: Glucose sensing in yeast and other cells
22. Grr1p of Saccharomyces cerevisiae is connected to the ubiquitin proteolysis machinery through Skp1p: Coupling glucose sensing to gene expression and the cell cycle
23. Glucose-regulated interaction of a regulatory subunit of protein phosphatase 1 with the Snf 1 protein kinase in Saccharomyces cerevisiae
24. The Saccharomyces cerevisiae gene SDS22 encodes a potential regulator of the mitotic function of yeast type 1 protein phosphatase
25. Characterization of the glucose-induced inactivation of maltose permease in Saccharomyces cerevisiae
26. The role of ubiquitin conjugation in glucose-induced proteolysis of Saccharomyces maltose permease
27. A PEST-like sequence in the N-terminal cytoplasmic domain of Saccharomyces maltose permease is required for glucose-induced proteolysis and rapid inactivation of transport activity
28. Three different regulatory mechanisms enable yeast hexose transporter (HXT) genes to be induced by different levels of glucose
29. Two glucose transporters in Saccharomyces cerevisiae are glucose sensors that generate a signal for induction of gene expression
30. REG1 binds to protein phosphatase type 1 and regulates glucose repression in Saccharomyces cerevisiae