IL-10 cooperates with TNF-α to activate HIV-1 from latently and acutely infected cells of monocyte/macrophage lineage

Journal of Immunology

Volumn 156, Issue 2, 1996, Pages 841-851

  Finnegan, Alison ^a,b   Roebuck, Kenneth A ^a   Nakai, Brian E ^a   Gu, D Sheng ^a   Rabbi, Mohammed F ^a   Song, Seng ^a   Landay, Alan L ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

^b RUSH MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 10; TUMOR NECROSIS FACTOR ALPHA; VIRUS RNA;

ARTICLE; CONTROLLED STUDY; DISEASE COURSE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MACROPHAGE; MONOCYTE; PRIORITY JOURNAL; VIRUS ACTIVATION; VIRUS REPLICATION;

BASE SEQUENCE; DRUG SYNERGISM; GENE EXPRESSION REGULATION, VIRAL; HIV LONG TERMINAL REPEAT; HIV-1; HUMANS; INTERLEUKIN-10; LYMPHOMA, LARGE-CELL; MACROPHAGES; MOLECULAR SEQUENCE DATA; MONOCYTES; NF-KAPPA B; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; RNA, VIRAL; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA; VIRUS ACTIVATION; VIRUS LATENCY; VIRUS REPLICATION;

EID: 0029670728     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. Lifson, A R., G. W. Rutherford, and H. W Jaffe. 1988. The natural history of human immunodeficiency virus infection J. Infect. Dis. 158.1360.
2. Dalgleish, A. G., P. C. L Beverley, P. R. Clapham, D H. Crawford, M F. Greaves, and R. A. Weiss 1984. The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus. Nature 312:763
3. Stewart, S. J., J. Fujimoto, and R Levy 1986. Human T lymphocytes and monocytes bear the some Leu3(T4) antigen. J. Immunol 136:3773
4. Nicholson, J K. A , D. Cross, C. S Callaway, and J S. McDougal, 1986 In vitro infection of human monocytes with human T lymphocytropic virus type III/ lymphadenopathy-associated virus (HTLV-III/LAV) J Immunol. 137:323
5. Koenig, S., H. E. Gendelman, J. M. Orenstein, M. C. Dalcanto, G. H. Pezeshkpour, M. Yungbluth, F Janotta, A. Aksamit, M A. Martin, and A S. Fauci. 1986. Detection of AIDS virus in macrophages in brain tissue from AIDS patterns with encephalopathy. Science 233:1089.
6. Gendelman, H E., J. M. Orenstein, L. M. Baca, B Weiser, H. Burger, D C Kalter, and M. S. Meltzer. 1989 The macrophage in the persistence and pathogenesis of HIV infection. AIDS 3:475.
7. Embret, J., M Zupancic, J. L Ribas, A. Burke, P Racz, K. Tenner-Racz, and A. Haase. 1993. Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS. Nature 362:359
8. Folks, T. M , K. A. Clouse, J Justement, A. Rabson, E Duh, J. H. Kehrl, and A. S Fauci. 1989. Tumor necrosis factor α induces expression of human immunodeficiency virus in a chronically infected T-cell clone. Proc Natl Acad. Sci. USA 86:2365.
9. Matsuyama, T., Y. Hamamoto, G.-I. Soma, D. Mizuno, N. Yamamoto, and N. Kobayashi 1989. Cytocidal effect of tumor necrosis factor on cells chronically infected with human immunodeficiency virus (HIV). enhancement of HIV replication. J. Virol. 63:2504.
10. Folks, T. M., J. Justement, A. Kinter, C A. Dinarello, and A S. Fauci. 1987 Cytokine-induced expression of HIV-1 in a chronically infected promonocyte cell line. Science 238:800.
11. Poli, G , A L Kinter, and A. S. Fauci. 1994. Interleukin 1 induces expression of the human immunodeficiency virus alone and in synergy with interleukin 6 in chronically infected U1 cells: inhibition of inductive effects by the interleukin 1 receptor antagonist. Proc Natl. Acad. Sci. USA 91:108.
12. Poli, G., P. Bressler, A Kinter, E Duh, W. C Timmer, A. Rabson, J S. Justement, S. Stanley, and A. S. Fauci. 1990. Interleukin 6 induces human immunodeficiency virus expression in infected monocytic cells alone and in synergy with tumor necrosis factor α by transcriptional and post-transcriptional mechanisms. J. Exp. Med. 172:151.
13. Schuitemaker, H., N. A. Kootstra, M. M. Koppelman, S. M. Bruisten, H. G. Huisman, M. Tersmette, and F. Miedema. 1992. Proliferation-dependent HIV-1 infection of monocytes, occurs during differentiation into macrophages. J. Clin. Invest. 89:1154.
14. Poli, G , A. L. Kinter, J. S Justement, P Bressler, J. H. Kehrl, and A. S Fauci. 1991. Transforming growth factor β suppresses human immunodeficiency virus expression and replication in infected cells of the monocyte/macrophage lineage. J. Exp. Med. 173:589
15. Chowdhury, M I., Y. Koyanagi, S. Horiuchi, O. Hazeki, M. Ui, K. Kitano, D. W. Golde, K Takada, and N. Yamamoto. 1993. cAMP stimulates human immunodeficiency virus (HIV-1) from latently infected cells of monocyte-macrophage lineage: synergism with TNF-α. Virology 194:345.
16. Bressler, P., G. Poli, J. S. Justement, P. Biswas, and A. S. Fauci. 1993. Glucocorticoids synergize with tumor necrosis factor α in the induction of HIV expression from chronically infected promonocytic cell line. AIDS Res. Hum. Retroviruses 9:547.
17. Clerici, M., T. A. Wynn, J. A Berzofsky, S. P Blatt, C. W. Hendrix, A. Sher, R L. Coffman, and G. M. Shearer. 1994 Role of interleukin-10 in T helper cell dysfunction in asymptomatic individuals infected with the human immunodeficiency virus. J. Clin. Invest. 93, 768.
18. Moore, K. W., A. O'Garra, R. de Waal Malefyt, P. Vieira, and T R Mosmann. 1993 Interleukin-10. Annu Rev. Immunol 11, 165.
19. Florentino, D. F., A. Zloik, P. Vieira, T R. Mosmann, M. Howard, K. W Moore, and A. O'Garra. 1991. IL-10 acts on the antigen-presenting cells to inhibit cytokine production by Th1 cells. J Immunol. 146:3444.
20. De Waal Malefyt, R., J. Abrams, B. Bennett, C. G. Figdot, and J. E. de Vries 1991 interleukin 10 (1L-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J Exp Med. 174:1209.
21. Wanidoworanun, C . and W. Strober. 1993 The predominant role of TNF-α on human monocyte IL-10 synthesis. J. Immunol. 151:6853
22. Denis, M , and E Ghadirian. 1994 Dysregulation of IL-8, IL-10, and IL-12 release by alveolar macrophages from HlV type I-infected subjects. AIDS Res. Hum. Retroviruses 10.1619
23. Akridge, R. E , L. K. M. Oyafuso, and S. G. Reed. 1994. IL-10 is induced during HIV-1 infection and is capable of decreasing viral replication in human macrophages J Immunol 153:5782.
24. Masood, R., Y. Lunardi-Iskandar, T. Moudgil, Y. Zhang, R. E. Law, C. Huang, R. K. Puri, A. M. Levine, and P S Gill 1994. IL-10 inhibits HIV-1 replication and is induced by Tat. Biochem. Biophys. Res. Commun. 202:374.
25. Borghi, P., L. Fantuzzi, B. Varano, S Gessani, P. Puddu, L Conti, M. R. Capobianchi, F. Arneglio, and F. Belardelli. 1995 Induction of interleukin-10 by human immunodeficiency virus type 1 and its gp120 protein in human monocytes/macrophages. J. Virol. 69 1284.
26. Saville, M. W., K. Taga, A Foli, S Broder, G. Tosato, and R. Yarchoan. 1994. Interleukin-10 suppresses human immunodeficiency virus-1 replication in vitro in cells of the monocyte/macrophage lineage. Blood 83:3591.
27. Weissman, D., G Poli, and A S. Fauci. 1994. Interleukin 10 blocks HIV replication in macrophages by inhibiting the autocrine loop of tumor necrosis factor or and interleukin 6 induction of virus AIDS Res. Hum. Retroviruses 10:1199.
28. Chang, J., S. Li, H. Naif, W Fear, M. Ho-Shon, and A L. Cunningham 1995. IL-10 suppress HlV replication in monocytes, monocyte-derived macrophages and placental macrophages and also contribute to impaired function of these cells. In Second Annual Conference on Hitman Retroviruses and Related Infections. American Society for Microbiology. Washington, DC, p 148.
29. Kootstra, N. A., A. B. van'T Wout, A. G. Huisman, F. Miedema, and H. Schuitemaker. 1994. Interference of IL-10 with HIV-1 replication in primary monocyte-derived macrophages. J. Virol. 68:6967.
30. Folks, T M., J Justement, A. Kinter, S. Schnittman, J. Orenstein, G. Poli, and A. S. Fauci. 1988 Characterization of a promonocyte clone chronically infected with HIV and inducible by 13-phorbol-12-myristate acetate. J. Immunol. 140: 1117.
31. Poli, G , and A. S. Fauci 1992. The effect of cytokines and pharmacologie agents on chronic HlV infection AIDS Res. Hum. Retroviruses 8:191.
32. Willey, R. L., D. H Smith, L. A. Lasky, T. S. Theodore, P. L. Earl, B. Moss, D. Capon, and M. A. Martin. 1988 In vitro mutagenesis identifies a region within the envelope gene of the human immunodeficiency virus that is critical for infectivity J. Virol. 62:139.
33. Roebuck, K. A , D A. Brenner, and M. F. Kagnoff. 1993 Identification of c-fos-responsive elements downstream of TAR in the long terminal repeat of human immunodeficiency virus type-1. J. Clin. Invest. 92:1336
34. Schreiber, E., P. Matthias, M. M Mueller, and W. Schaffner. 1989. Rapid detection of octamer binding proteins with mini-extracts prepared from a small number of cells. Nucleic Acids Res. 17-6419.
35. Felber, B., and G. N. Pavlakis. 1988. A quantitative bioassay for HIV-1 bases on trans-activation. Science 239:184.
36. Poli, G., A. Kinter, J. S. Justement, J. H. Kehrl, P. Bressler, S. Stanley, and A. S. Fauci 1990. Tumor necrosis factor α functions in an autocrine manner in the induction of human immunodeficiency virus expression. Proc. Natl. Acad. Sci. USA 87.782.
37. + model of chronic infection. J. Immunol. 150:625
38. Nabel, G., and D. Baltimore. 1987. An inducible transcription factor activates expression of human immunodeficiency virus in T cells. Nature 326:711.
39. Weissman, D., G. Poli, and A. S. Fauci. 1995. IL-10 synergizes with multiple cytokines in enhancing HIV production in cells of monocytic lineage. J. Acquir Immune Defic Synd. Hum. Retrovirol. 9.442.
40. Angel, J. B., B M. Saget, C. A. Dinarello, and P R. Skolnik 1995. Interleukin-10 enhances HIV-1 expression in a chronically infected promonocytic cell line (U1) by a TNF-α-independent mechanism. In Second Annual Conference on Human Retroviruses and Related Infections. American Society for Microbiology, Washington, DC, p. 84
41. Schreck, R., B. Meier, D. N. Mannel, W Dorge, and P. A Baeuerle. 1992. Dithiocarbamate as potent inhibitors of nuclear factor κB activation in intact cells. J. Exp. Med 175:1181.
42. Finbloom, D S , and K. D. Winestock 1995. IL-10 induces the tyrosine phosphorylation of tyk2 and Jak1 and the differential assembly of STAT1α and STAT3 complexes in human T cells and monocytes. J. Immunol. 155:1079.
43. Fu, X-Y., and J.-J. Zhang. 1993. Transcription factor p91 interacts with the epidermal growth factor receptor and mediates activation of the c-fos gene promoter Cell 74:1135.
44. Stein, B., A. S Baldwin, D. W. Ballard, W. C. Greene, P. Angel, and P. Herrlich. 1993. Cross-coupling of the NF-κB p65 and Fos/Jun transcription factors produced potentiated biological function. EMBO J. 12:3879.
45. Wang, P , P Wu, M. I Siegal, R. W. Egan, and M. M. Billah. 1994. IL-10 inhibits transcription of cytokine genes in human peripheral blood mononuclear cells. J Immunol. 153 811
46. Montaner, L. J., P. Griffin, and S. Gordon. 1994. Interleukin-10 inhibits initial reverse transcription of human immunodeficiency virus type 1 and mediates a virostatic latent state an primary blood-derived human macrophages in vitro. J. Gen. Virol. 75:3393.
47. D'Andres, A., M. Rengaraju, N. M. Valiante, J. Chehimi, M Kuban, M. Aste, S. H. Chan, M Kobayashi, D. Young, E Nickbarg, S F. Wolf, and G. Trinchieri. 1992. Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells. J Exp Med. 176:1387.
48. Trinchieri, G. 1993. Interleukin-12 and its role in the generation of Th1 cells. Immunol Today 14.335.
49. Chehimi, J., S. E Starr, I. Frank, A. D'Andres, X. Ma, R. R MacGregor, J. Sennelier, and G. Tnnchien 1994. Impaired interleukin 12 production in human immunodeficiency virus-infected patients. J. Exp Med. 179:1361.
50. McKiel, V., M Wainberg, and J. Hiscott. 1993. Antiviral effects of IL-10 and TGF-β1 in HIV infected myelomonoblastic cells J. Cell. Biochem. Suppl. 18B: J252.