Chemoprevention by nimesulide, a selective cyclooxygenase-2 inhibitor, of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced mammary gland carcinogenesis in rats

Japanese Journal of Cancer Research

Volumn 91, Issue 9, 2000, Pages 886-892

  Nakatsugi, Seiichi ^a,b   Ohta, Toshihisa ^a   Kawamori, Toshihiko ^a   Mutoh, Michihiro ^a   Tanigawa, Tetsuya ^a   Watanabe, Kouji ^a   Sugie, Shigeyuki ^c   Sugimura, Takashi ^a   Wakabayashi, Keiji ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b SAWAI PHARMACEUTICAL CO LTD   (Japan)

^c GIFU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Chemoprevention; COX 2 inhibitor; Mammary gland cancer; Nimesulide; PhIP

Indexed keywords

2 AMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; BENZYLSULFONYL FLUORIDE; CARCINOGEN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; DEOXYCHOLATE SODIUM; DODECYL SULFATE SODIUM; EOSIN; FAT; FORMALDEHYDE; HEMATOXYLIN; IMMUNOGLOBULIN G ANTIBODY; MONOCLONAL ANTIBODY; NIMESULIDE; POLYACRYLAMIDE; POLYVINYLIDENE FLUORIDE; SODIUM AZIDE; SODIUM CHLORIDE; TROMETAMOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST BIOPSY; BREAST CANCER; BREAST CARCINOGENESIS; CANCER GROWTH; CANCER INCIDENCE; CANCER PREVENTION; CARCINOMA CELL; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; ENZYME INHIBITION; FEMALE; GROWTH INHIBITION; HISTOPATHOLOGY; IMMUNOBLOTTING; LIPID DIET; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STROMA CELL;

ANIMAL; ANTICARCINOGENIC AGENTS; CARCINOGENS; CYCLOOXYGENASE INHIBITORS; FEMALE; IMIDAZOLES; IMMUNOHISTOCHEMISTRY; MAMMARY NEOPLASMS, EXPERIMENTAL; RATS; RATS, SPRAGUE-DAWLEY; SULFONAMIDES; SUPPORT, NON-U.S. GOV'T;

EID: 0033778451     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2000.tb01030.x     Document Type: Article

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