Psychological consequences of predictive genetic testing: A systematic review

European Journal of Human Genetics

Volumn 8, Issue 10, 2000, Pages 731-738

  Broadstock, Marita ^a,c   Michie, Susan ^b   Marteau, Theresa ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Breast cancer; Familial adenomatous polyposis; Genetic testing; Huntington's disease; Ovarian cancer; Predictive testing; Psychological consequences; Spinocerebellar ataxia; Systematic review

Indexed keywords

ADOLESCENT; ADULT; ANXIETY; BREAST CANCER; CEREBELLAR ATAXIA; CHILD; CLINICAL PROTOCOL; COMPARATIVE STUDY; CONTROLLED STUDY; DATA ANALYSIS; DEPRESSION; FAMILIAL COLON POLYPOSIS; FAMILIAL DISEASE; FEMALE; FOLLOW UP; GENETIC ANALYSIS; GENETIC SUSCEPTIBILITY; HEREDITARY ATAXIA; HETEROZYGOTE DETECTION; HUMAN; HUNTINGTON CHOREA; MAJOR CLINICAL STUDY; MALE; MEDICAL LITERATURE; MENTAL STRESS; OUTCOMES RESEARCH; OVARY CANCER; PREDICTION; PRIORITY JOURNAL; PSYCHOLOGIC ASSESSMENT; REVIEW; RISK ASSESSMENT; STANDARDIZATION; STATISTICAL ANALYSIS;

ADAPTATION, PSYCHOLOGICAL; ADULT; CHILD; FEMALE; GENETIC COUNSELING; GENETIC DISEASES, INBORN; GENETIC SCREENING; HUMANS; MALE; STRESS, PSYCHOLOGICAL;

ATAXIA;

EID: 0033777223     PISSN: 10184813     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ejhg.5200532     Document Type: Review

References (73)

1. Psychological impact of predicting individual's risk of illness: A systematic review
2. Predictors of psychological adjustment to genetic testing for Huntington's disease
3. Prediction of psychological functioning one year after the predictive test for Huntington's disease and impact of the test result on reproductive decision making
4. The psychological consequences of predictive testing for Huntington's disease
5. Adverse psychological events occurring in the first year after predictive testing for Huntington's disease
6. Exploration of the effects of predictive testing for Huntington disease on intimate relationships
7. Presymptomatic DNA testing for Huntington disease: Identifying the need for psychological intervention
8. Psychological effects of presymptomatic DNA testing for Huntington's disease in the Dutch program
9. Three-year follow-up after presymptomatic testing for Huntington's disease in tested individuals and partners
10. Course of distress experienced by persons at risk for an autosomal dominant inherited disorder participating in a predictive testing program: An exploratory study
11. Predicting adaptation to presymptomatic DNA-testing for late onset disorders: Who will experience distress?
12. Psychological responses to BRCA1 mutation testing: Preliminary findings
13. BRCA1 testing in families with hereditary breast-ovarian cancer: A prospective study of patient decision making and outcomes
14. What you don't know can hurt you: Adverse psychologic effects in members of BRCA1-linked and BRCA2-linked families who decline genetic testing
15. Genetic testing for cancer in children. Short-term psychological effect
16. Psychological consequences of genetic testing for spinocerebellar ataxia in the Japanese
17. Genetic testing for cancer predisposition
18. Few psychological consequences of presymptomatic testing for Huntington disease
19. Psychological opportunities and hazards in predictive genetic testing for cancer risk
20. The genetic testing of children
21. Genetic testing for cancer risk: How to reconcile the conflicts
22. The new genetics: Psychological responses to genetic testing
23. Psychological consequences of presymptomatic testing for Huntington's disease
24. Genetic testing of families with hereditary diseases
25. Presymptomatic DNA-testing for Huntington disease in the Netherlands
26. Presymptomatic testing for Huntington's disease. Emotional aspects
27. Predictive testing for Huntington disease in Canada: The experience of those receiving an increased risk
28. Presymptomatic DNA testing for Huntington's disease
29. Genetic testing and Huntington's disease
30. Psychosocial consequences of DNA analysis for MEN type 2
31. Genetic testing for Huntington's disease - A family issue
32. Predictive testing for Huntington disease: Social characteristics and knowledge of applicants, attitudes to the test procedure and decisions made after testing
33. Predictive testing for Huntington disease in Canada: Adverse effects and unexpected results in those receiving a decreased risk
34. DNA screening for breast/ovarian cancer susceptibility based on linked markers
35. Long-term impact of Huntington disease linkage testing
36. Psychosocial impact of testing (by linkage) for the BRCA1 breast cancer gene - An investigation of 2 families in the research setting
37. Predictive testing for Huntington's disease: Risk perception, reasons for testing and psychological profile of test applicants
38. Non-participation in predictive testing for Huntington's disease: Individual decision-making, personality and avoidant behaviour in the family
39. Psychological distress in applicants for predictive DNA testing for autosomnal dominant, heritable, late onset disorders
40. Distress in individuals facing predictive DNA testing for autosomnal dominant late-onset disorders: Comparing questionnaire results with in-depth interviews
41. A controlled psychiatric study of individuals at risk for Huntingtons Disease
42. Presymptomatic testing for Huntington's disease in Wales 1987-90
43. Predictive testing for Huntington disease: Non-participants compared with participants in the Dutch program
44. Psychological costs and benefits of predictive testing for Huntington's disease
45. On attitudes and appreciation 6 months after predictive DNA testing for Huntington disease in the Dutch program
46. Familial context of genetic testing for cancer susceptibility: Moderating effect of siblings' test results on psychological distress one to two weeks after BRCA1 mutation testing
47. DNA-testing for Huntington's disease in The Netherlands: A retrospective study on psychosocial effects
48. An inventory for measuring depression
49. The measurement of pessimism: The Hopelessness Scale
50. The CES-D Scale: A self-report depression scale for research in the general population
51. A new scale of social desirability independent of psychopathology
52. Role functioning measures
53. Social functioning: Sexual problems measured
54. Impact of Event Scale: A measure of subjective stress
55. A brief measure of social support: Practical and theoretical implications
56. The development of a Rasch-type Loneliness Scale
57. A worldwide assessment of the frequency of suicide, suicide attempts, or psychiatric hospitalization after testing for Huntington Disase
58. Outrageous fortune: The risk of suicide in genetic testing for Huntington Disease
59. Processing risk factor information: Defensive biases in health-related judgments and memory
60. Predictive genetic testing in children and adults: A study of emotional impact
61. Will genetic testing for predisposition for disease result in fatalism? A qualitative study of parents responses to neonatal screening for familial hyper-cholesterolaemia
62. Molecular Genetics and Moral Responsibility; 'maybe if I were working on the atom bomb I would have a different argument'