메뉴 건너뛰기




Volumn 16, Issue 4, 2000, Pages 257-273

The effect of the trichloroethylene metabolites trichloroacetate and dichloroacetate on peroxisome proliferation and DNA synthesis in cultured human hepatocytes

Author keywords

Cell proliferation; Dichloroacetate; Human hepatocytes; Peroxisome proliferation; Trichloroacetate; Trichloroethylene

Indexed keywords

CARCINOGEN; CYTOCHROME P450; DICHLOROACETIC ACID; DNA; PALMITOYL COENZYME A; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PIRINIXIC ACID; TRICHLOROACETIC ACID; TRICHLOROETHYLENE;

EID: 0033773932     PISSN: 07422091     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007638227821     Document Type: Article
Times cited : (17)

References (63)
  • 2
    • 0007551747 scopus 로고    scopus 로고
    • ATSDR, US Department of Health and Human Services, Agency for Toxic Substances and Disease Registry. Toxicologic profile for trichloroethylene
    • (1997)
  • 12
    • 0025847539 scopus 로고
    • Evidence for and possible mechanisms of non-genotoxic carcinogenesis in rodent liver
    • (1981) Mutat Res , vol.248 , pp. 271-290
    • Cohen, A.J.1    Grasso, P.2
  • 16
    • 0028137509 scopus 로고
    • Trichloroacetate stimulation of liver DNA synthesis in male and female mice
    • (1994) Toxicol Lett , vol.70 , Issue.3 , pp. 343-355
    • Dees, C.1    Travis, C.2
  • 20
    • 0022335175 scopus 로고
    • Species differences in carcinogenicity and peroxisome proliferation due to trichloroethylene: A biochemical human hazard assessment
    • (1985) Arch Toxicol Suppl , vol.8 , pp. 6-17
    • Elcombe, C.R.1
  • 34
    • 0029776373 scopus 로고    scopus 로고
    • Species differences in response to peroxisome proliferators correlate in vitro with induction of DNA synthesis rather than suppression of apoptosis
    • (1996) Carcinogenesis , vol.17 , Issue.8 , pp. 1623-1632
    • James, N.H.1    Roberts, R.A.2
  • 35
    • 0031409897 scopus 로고    scopus 로고
    • Induction of replicative DNA synthesis and PPARα-dependent gene transcription by Wy-14,643 in primary rat hepatocyte and non-parenchymal cell co-cultures
    • (1997) Carcinogenesis , vol.18 , Issue.11 , pp. 2077-2083
    • Karam, W.G.1    Ghanayem, B.I.2
  • 37
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 41
    • 0024241608 scopus 로고
    • Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (WY-14,643) in rats
    • (1988) Cancer Res , vol.48 , pp. 6739-6744
    • Marsman, D.S.1    Cattley, R.C.2    Conway, J.G.3    Popp, J.A.4
  • 42
  • 44
    • 0003496870 scopus 로고
    • NTP Technical Report; no. 243
    • (1990) 1 mice
  • 49
    • 0032536188 scopus 로고    scopus 로고
    • Rodent hepatocarcinogenic peroxisome proliferators induce proliferation of rat hepatocytes in primary mixed cultures with rat liver epithelial cells
    • (1998) Cancer Lett , vol.123 , pp. 27-33
    • Perrone, C.E.1    Williams, G.M.2
  • 52
    • 0024430314 scopus 로고
    • Oxidative DNA damage caused by persistent peroxisome proliferation: Its role in hepatocarcinogenesis
    • (1989) Mutat Res , vol.214 , pp. 63-68
    • Reddy, J.K.1    Rao, M.S.2
  • 57
    • 0031172480 scopus 로고    scopus 로고
    • Differences in phenotype and cell replicative behavior of hepatic tumors induced by dichloroacetic acid (DCA) and trichloroacetic acid (TCA)
    • (1997) Toxicol Appl Pharmacol , vol.144 , pp. 235-246
    • Stauber, A.J.1    Bull, R.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.