Transcription inhibitors stimulate translation of 5' TOP mRNAs through activation of S6 kinase and the mTOR/FRAP signalling pathway

European Journal of Biochemistry

Volumn 267, Issue 22, 2000, Pages 6594-6601

  Loreni, Fabrizio ^a   Thomas, George ^b   Amaldi, Francesco ^a,c  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^c Dipartimento di Biologia   (Italy)

Author keywords

Actinomycin D; mRNAs; mTOR FRAP pathway; TOP S6K1; Translational control

Indexed keywords

5,6 DICHLOROBENZIMIDAZOLE RIBOSIDE; ALPHA AMANITIN; CORDYCEPIN; DACTINOMYCIN; MESSENGER RNA; PYRIMIDINE DERIVATIVE; RAPAMYCIN; RIBOSOME PROTEIN; S6 KINASE;

5' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVATION; GENE ACTIVATION; GENE REPRESSION; HUMAN; HUMAN CELL; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; RNA TRANSLATION; SIGNAL TRANSDUCTION;

AMANITINS; ANIMALS; CELL CYCLE PROTEINS; CELLS, CULTURED; DACTINOMYCIN; DEOXYADENOSINES; DICHLORORIBOFURANOSYLBENZIMIDAZOLE; ENZYME ACTIVATION; KIDNEY; NUCLEIC ACID SYNTHESIS INHIBITORS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN BIOSYNTHESIS; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; RIBOSOMAL PROTEIN S6 KINASES; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; VERTEBRATES; XENOPUS LAEVIS; XENOPUS PROTEINS;

AMPHIBIA; ANIMALIA; MAMMALIA; VERTEBRATA;

EID: 0033773874     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2000.01753.x     Document Type: Article

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