Centrosome-centriole abnormalities are markers for abnormal cell divisions and cancer in the transgenic adenocarcinoma mouse prostate (TRAMP) model

Biology of the Cell

Volumn 92, Issue 5, 2000, Pages 331-340

  Schatten, Heide ^a   Wiedemeier, Allison M D ^a   Taylor, Meghan ^a   Lubahn, Dennis B ^a   Greenberg, Norman M ^b   Besch Williford, Cynthia ^a   Rosenfeld, Cheryl S ^a   Kevin Day, J ^a   Ripple, Maureen ^c  

^a UNIVERSITY OF MISSOURI   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Apoptosis; Cell proliferation; Centrosomes; Cytoskeleton; Prostate cancer

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER MODEL; CELL CYCLE; CELL DIVISION; CELL POLARITY; CENTRIOLE; CENTROSOME; CHROMOSOME ABERRATION; COMPLEX FORMATION; CONTROLLED STUDY; DISEASE MARKER; ELECTRON MICROSCOPY; GENETIC STABILITY; HISTOLOGY; INTERPHASE; MALIGNANT NEOPLASTIC DISEASE; MICROTUBULE ASSEMBLY; MITOSIS; MITOSIS SPINDLE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE ADENOCARCINOMA; TRANSGENIC MOUSE; TUMOR CELL;

ANIMALIA; MUS MUSCULUS;

EID: 0033772386     PISSN: 02484900     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0248-4900(00)01079-0     Document Type: Article

References (40)

1. The centrosome in animal cells and its functional homologs in plant and yeast cells
2. Zellen-Studien IV: Ueber die Natur der Centrosomen Jena
3. Microtubule organizing centers
4. Supernumerary centrosomes and cancer: Boveri's hypothesis resurrected
5. Are centrosomes or aneuploidy the key to cancer?
6. Characterization of prostatic epithelial cell lines derived from transgenic adenocarcinoma of the mouse prostate (TRAMP) model
7. A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators
8. Abnormal centrosome amplification in the absence of p53
9. Chemically induced aneuploidy in mammalian cells in culture
10. A transgenic mouse prostate cancer model
11. Metastastic prostate cancer in a transgenic mouse
12. The rat probasin gene promotor directs hormonally and developmentally regulated expression of a heterologous gene specifically to the prostate in transgenic mice
13. Prostate cancer in transgenic mouse
14. Requirement of Cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extracts
15. The centrosomal cycle: Visualization in PtK cells by a monoclonal antibody to centrosomal 32 kDa protein
16. Murine cDNAs coding for the centrosomal antigen centrosomin
17. Centriole distribution during tripolar mitosis in Chinese hamster
18. Manipulation of T cell costimulatory and inhibitory signals for immunotherapy of prostate cancer
19. A study of the induction of aneuploidy and chromosome aberrations after diazepam, medazolam and bromazepam treatment
20. Centrosome hypertrophy in human breast tumors: Implications for genomic stability and cell polarity
21. Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene
22. Aotoantibodies to a group of centrosomal proteins in human autoimmune sera reactive with the centrosome
23. Protein kinases in control of the centrosome cycle
24. Centrosomes and mitotic poles
25. Identification of γ-tubulin, a new member of the tubulin superfamily encoded by mipA gene of Aspergillus nidulans
26. Centrosomes and cancer
27. Dithiothreitol prevents membrane fusion but not centrosome or microtubule organization during the first cell cycles in sea urchins
28. Centrosome structure and function is altered by chloral hydrate and diazepam during the first reproductive cell cycles in sea urchin eggs
29. Behavior of centrosomes during fertilization and cell division in mouse oocytes and sea urchin eggs
30. Centrosome detection in sea urchin eggs with a monoclonal antibody against Drosophila intermediate filament proteins: Characterization of stages of the division cycle of centrosomes
31. Centrosome abnormalities in cancer cells and tissue
32. Centrosome and microtubule instability in aging Drosophila cells
33. Androgen and taxol cause cell type specific alterations of centrosome and DNA organization in androgen-responsive LNCaP and androgen independent DU145 prostate cancer cells
34. Centrosome alterations induced by formamide cause abnormal spindle pole formations
35. Cell Polarity and Centrosomes
36. Tumor promoter-induced centrosome splitting in human polymorphonuclear leukocytes
37. Phosphoproteins are components of mitotic microtubule organizing centers
38. Large fragment of the probasin promoter targets high levels of transgene expression to the prostate of transgenic mice