Differential susceptibility to CD95 (Apo-1/Fas) and MHC class II-induced apoptosis during murine dendritic cell development

Cell Death and Differentiation

Volumn 7, Issue 10, 2000, Pages 933-938

  McLellan, A D ^a   Terbeck, G ^a   Mengling, T ^a   Starling, G C ^b   Kiener, P A ^b   Gold, R ^a   Brocker E B ^a   Leverkus, M ^a   Kampgen E ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b BRISTOL MYERS SQUIBB PHARMACEUTICAL RESEARCH INSTITUTE   (United States)

Author keywords

Apoptosis; Caspases; CD95; Dendritic cell; MHC class II

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE INHIBITOR; FAS ANTIGEN; FAS LIGAND; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PHOSPHATIDYLSERINE;

ANIMAL CELL; ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; ANTIGEN SPECIFICITY; APOPTOSIS; ARTICLE; BONE MARROW; BONE MARROW CULTURE; CELL DEATH; CELL KILLING; CELL MATURATION; CELL SURFACE; CONTROLLED STUDY; DENDRITIC CELL; DEPOLARIZATION; ENZYME ACTIVATION; EPIDERMIS; EXPOSURE; LYMPH NODE; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SPLEEN; T LYMPHOCYTE; THYMOCYTE;

EID: 0033769855     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400734     Document Type: Article

References (36)

1. Dendritic cells: Unique leukocyte populations which control the primary immune response
2. Dendritic cells and the control of immunity
3. Functions of myeloid and lymphoid dendritic cells
4. In vivo detection of dendritic cell antigen presentation to CD4(+) T cells
5. Lymph-borne dendritic leukocytes do not recirculate, but enter the lymph node paracortex to become interdigitating cells
6. Migration patterns of dendritic cells in the mouse. Traffic from the blood, and T cell-dependent and -independent entry to lymphoid tissues
7. Systemic migration of dendritic cells during contact sensitization
8. Dendritic cells undergo rapid apoptosis in vitro during antigen-specific interaction with CD4+ T cells
9. CD95(APO-1/Fas)-mediated apoptosis: Live and let die
10. CD95 ligand (CD95L) in normal human lymphoid tissues: A subset of plasma cells are prominent producers of CD95L
11. Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)
12. Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation
13. Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas
14. Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor
15. Bid, a Bc12 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
16. CD40 ligation counteracts Fas-induced apoptosis of human dendritic cells
17. CD40 ligand inhibits Fas/CD95-mediated apoptosis of human blood-derived dendritic cells
18. In vitro expansion of CD13+CD33+ dendritic cell precursors from multipotent progenitors is regulated by a discrete fas-mediated apoptotic schedule
19. Maturation of dendritic cells upregulation of cellular FLICE-inhibitory protein (cFLIP) and concomitant downregulation of death ligand-mediated apoptosis
20. An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow
21. Ligation of major histocompatibility complex class II molecules mediates apoptotic cell death in resting B lymphocytes
22. Triggering HLA-DR molecules on human peripheral monocytes induces their death
23. MHC class II and CD40 play opposing roles in dendritic cell survival
24. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor
25. TGF-beta 1 promotes in vitro generation of dendritic cells by protecting progenitor cells from apoptosis
26. Propriocidal apoptosis of mature T lymphocytes occurs at S phase of the cell cycle
27. Cell cycle-dependent regulation of FLIP levels and susceptibility to Fas-mediated apoptosis
28. Two CD95 (APO-1/Fas) signaling pathways
29. Differential modulation of apoptosis sensitivity in CD95 type I and type II cells
30. Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphopro-liferative syndrome type II
31. Mechanisms of tolerance induction in major histocompatibility complex class II-restricted T cells specific for a blood-borne self-antigen
32. Increased level of intracellular MHC class II molecules in murine Langerhans cells following in vivo and in vitro administration of contact allergens
33. Class II major histocompatibility complex molecules of murine dendritic cells: Synthesis, sialylation of invariant chain, and antigen processing capacity are down-regulated upon culture
34. Identification of amino acid residues important for ligand binding to Fas
35. Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo
36. A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis