Is greater tissue activity of creatine kinase the genetic factor increasing hypertension risk in black people of sub-Saharan African descent?

Journal of Hypertension

Volumn 18, Issue 11, 2000, Pages 1537-1544

  Brewster, Lizzy M ^a,b   Clark, Joseph F ^a   Van Montfrans, Gert A ^b  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Blacks; Cerebrovascular disorders; Creatine kinase; Genetics; Hypertension; Kidney failure; Left ventricular hypertrophy; Myocardial infarction; Salt sensitivity; Smooth muscle

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CREATINE KINASE; PROTON;

AFRICA; CARDIOVASCULAR RISK; DISEASE ASSOCIATION; ENZYME ACTIVITY; GENETIC PREDISPOSITION; HEART MUSCLE CONTRACTILITY; HEART MUSCLE ISCHEMIA; HUMAN; HYPERTENSION; KIDNEY FAILURE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; RISK FACTOR; SMOOTH MUSCLE CONTRACTILITY; STROKE;

EID: 0033762442     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004872-200018110-00002     Document Type: Review

References (70)

1. Hypertension in populations of West-African origin: Is there a genetic predisposition?
2. Essential hypertension racial/ethnic differences in pathophysiology
3. Blood pressure variation in blacks: Genetic factors
4. Psychosocial factors in hypertension in blacks: The case for an interactional perspective
5. Pathophysiology and treatment implications of hypertension in the African-American population
6. Longitudinal assessment of blood pressures in black and white children
7. Systolic blood pressure differences in black, colored, and white infants
8. Attenuation of cyclic nucleotide-mediated smooth muscle relaxation in blacks as a cause of racial differences in vasodilator function
9. The role of cardiovascular reactivity as a mediator of hypertension in African Americans
10. Cardiovascular and plasma catecholamine responses to exercise in blacks and whites
11. Blackwhite differences in exercise blood pressure. The Lipid Research Clinics Program Prevalence Study
12. Responses to ergometer exercise in a healthy biracial population of children
13. Association of hypertension with beta2- and alpha2c10-adrenergic receptor genotype
14. Haplotype analysis of CYP11B2
15. The biological concept of race and its application to public health and epidemiology
16. Skeletal muscle characteristics in sedentary black and Caucasian males
17. Creatine kinase in non-muscle tissues and cells
18. The creatine kinase system in smooth muscle
19. Whole-organ enzymology of the creatine kinase system in heart
20. The importance of the creatine kinase reaction: The concept of metabolic capacitance
21. Metabolic control and metabolic capacity: Two aspects of creatine kinase functioning in the cells
22. Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins
23. Molecular characterization of the creatine kinases and some historical perspectives
24. Comparison of endogenous and exogenous sources of ATP in fueling Ca2+ uptake in smooth muscle plasma membrane vesicles
25. Demonstration of a digitalis-sensitive sarcolemmal Ca2+-pump functionally coupled with a membrane associated creatine phosphokinase
26. Myofibrillar creatine kinase and cardiac contraction
27. A review of the actions and control of intracellutar pH in vascular smooth muscle
28. Effects of changes of pH on the contractile function of cardiac muscle
29. Pharmacomechanical coupling: The role of calcium, G-proteins, kinases and phosphatases
30. What is special about smooth muscle? The significance of covalent crossbridge regulation
31. Cross-bridge phosphorylation and regulation of latch state in smooth muscle
32. MgADP promotes a catch-like state developed through force-calcium hysteresis in tonic smooth muscle
33. Effects of high-energy phosphates on carbachol-evoked cationic current in Single smooth muscle cells from guinea-pig ileum
34. ATP-dependent control of steady-state cytosolic calcium in cultured gastric smooth muscle
35. Differences in platelet calcium regulation between African Americans and Caucasians: Implications for the predisposition of African Americans to essential hypertension
36. The hemodynamic importance of structural vascular changes in essential hypertension
37. Dynamics of blood and lymph flow
38. Phosphocreatine and creatine kinase in energetic metabolism of the porcine carotid artery
39. Creatine kinase activity associated with the contractile proteins of the guinea-pig carotid artery
40. Role of creatine phosphokinase in cellular function and metabolism
41. Creatine kinase system in failing and nonfailing human myocardium
42. Inhibition of the creatine kinase reaction decreases the contractile reserve of isolated rat hearts
43. Bioenergetic consequences of cardiac phosphocreatine depletion induced by creatine analogue feeding
44. Adaptation of cardiac contractile function to conditions of chronic energy deficiency
45. Luminal calcium regulation of calcium release from sarcoplasmic reticulum
46. Creatine kinase is the main target of reactive oxygen species in cardiac myofibrils
47. Mitochondrial creatioe kinase is a prime target of peroxynitrite-induced modification and inactivation
48. Creatine kinase as an intracellular regulator
49. Expression of creatine kinase isoenzyme during oogenesis and embryogenesis in the mouse
50. Characteristics of prehypertension in black children
51. Growth factors and racial differences in severity of hypertension and renal disease
52. Malignant hypertension in blacks. Malignant intrarenal arterial disease as observed by light and electron microscopy
53. Molecular biology of the renin cascade in hypertension [clinical conference]
54. Physiology of renal sodium transport
55. Coronary disease: Black-white differences
56. Myocardial infarction in treated hypertensive patients: The paradox of lower incidence but higher mortality in young blacks compared with whites
57. Ethnic differences in stroke; black-white differences in the United States population. SECORDS Investigators. Southeastern Consortium on Racial Differences in Stroke
58. Ethnic differences in incidence of stroke prospective study with stroke register
59. Enzyme activities in type I and II muscle fibres of human skeletal muscle in relation to age and torque development
60. Special capabilities of the sexes: Differences in the molecular repertoire of mammal brain, heart and skeletal muscle
61. Impact of testosterone and oestradiol on region specificity of skeletal muscle-ATP, creatine phosphokinase and myokinase in male and female Wistar rats
62. Higher relative, but lower absolute risks of myocardial infarction in women than in men: Analysis of some major risk factors in the SHEEP study
63. Abnormal myocardial phosphorus-31 nuclear magnetic resonance spectroscopy in women with chest pain but normal coronary angiograms
64. The effects of anti-hypertensive therapy on the structural, mechanical, and metabolic properties of the rat aorta
65. Mitochondrial energy metabolism in the left ventricular tissue of spontaneously hypertensive rats: Abnormalities in both adeninenucleotide and phosphate translocators and enzyme adenylate-kinase and creatine-phosphokinase activities
66. Changes in arterial smooth muscle contractility, contractile proteins, and arterial wall structure in spontaneous hypertension
67. Evidence that the increased calcium sensitivity of resistance vessels in spontaneously hypertensive rats is an intrinsic defect of their vascular smooth muscle
68. Decreased vascular relaxation in hypertension
69. Vascular relaxation in the spontaneously hypertensive rat
70. On the logic of causal interference