Cytotoxic γδ or αβ T Cells with a Natural Killer Cell Marker, CD56, Induced from Human Peripheral Blood Lymphocytes by a Combination of IL-12 and IL-2

Journal of Immunology

Volumn 157, Issue 9, 1996, Pages 3886-3892

  Satoh, Masayuki ^a   Seki, Shuhji ^b,c   Hashimoto, Wataru ^d   Ogasawara, Kouetsu ^d   Kobayashi, Terutada ^a   Kumagai, Katsuo ^d   Matsuno, Seiki ^a   Takeda, Kazuyoshi ^c  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b National Defense Force   (Japan)

^c NIIGATA UNIVERSITY   (Japan)

^d TOHOKU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CD3 ANTIGEN; CD56 ANTIGEN; INTERLEUKIN 12; INTERLEUKIN 2; LYMPHOCYTE ANTIGEN RECEPTOR;

ARTICLE; CHEMISTRY; CYTOLOGY; DRUG EFFECT; HUMAN; IMMUNOLOGY; LIVER; LYMPHOCYTE ACTIVATION; NATURAL KILLER CELL; T LYMPHOCYTE SUBPOPULATION;

ANTIGENS, CD3; ANTIGENS, CD56; BIOLOGICAL MARKERS; HUMANS; INTERLEUKIN-12; INTERLEUKIN-2; KILLER CELLS, NATURAL; LIVER; LYMPHOCYTE ACTIVATION; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; T-LYMPHOCYTE SUBSETS;

EID: 0030294654     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Kobayashi, M., L. Fitz, M. Ryan, R. M. Hewick, S. C. Clark, S. Chan, R. Loudon, F. Sherman, B. Perussia, and G. Trinchieri. 1989. Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes. J. Exp. Med. 170:827.
2. Stern, A. S., F. J. Podlaski, J. D. Hulmes, V. C. Pan, P. M. Quinn, A. G. Wolitzky, P. C. Familletti, D. L. Stremlo, T. Truitt, R. Chizzonite, and M K. Gately. 1990. Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells. Proc. Natl. Acad. Sci. USA 87:6808.
3. Gately, M. K., B. B. Desai, A. G. Wolitzky, P. M. Quinn, C. M. Dwyer, F. J. Podlaski, P. C. Familletti, F. Sinigaglia, R. Chizzonite, U. Gubler, and A. S. Stern. 1991. Regulation of human lymphocyte proliferation by a heterodimeric cytokine, IL-12 (cytotoxic lymphocyte maturation factor). J. Immunol. 147:874.
4. Wolf, S. F., P. A. Temple, M. Kobayashi, D. Young, M. Dicig, L. Lowe, R. Dzialo, L. Fitz, C. Ferenz, R. M. Hewick, K. Kelleher, S. H. Hermann, S. C. Clark, L. Azzoni, S. H. Chan, G. Trinchieri, and B. Perussia. 1991. Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells. J. Immunol. 146:3074.
5. Schoenhaut, D. S., A. O. Chua, A. G. Wolitzky, P. M. Quinn, C. M. Dwyer, W. McComas, P. C. Familletti, M. K. Gately, and U. Gubler. 1992. Cloning and expression of murine IL-12. J. Immunol. 148:3433.
6. Nastala, C. L., H. D. Edington, T. G. McKinney, H. Tahara, M. A. Nalesnik, M. J. Brunda, M. K. Gately, S. F. Wolf, R. D. Schreiber, W. J. Storkus, and M. T. Lotze. 1994. Recombinant IL-12 administration induces tumor regression in association with IFN-γ production. J. Immunol. 153:1697.
7. Gately, M. K., R. Warrier, S. Honasoge, D. Cavajal, D. Faherty, S. Connaughton, T. Anderson, U. Sarmiento, B. Hubbard, and M. Murphy. 1994. Administration of recombinant IL-12 to normal mice enhances the cytolytic lymphocyte activity and induces the production of interferon-gamma in vivo. Int. Immunol. 6:157.
8. + αβ T cells with intermediate TCR induced in the liver of mice by IL-12. J. Immunol. 154:4333.
9. + αβ T cells with potent cytotoxicity in the liver of mice via production of IL-12 from Kupffer cells. J. Immunol. 156:2436.
10. + cells derived from T cells with potent in vivo antitumor activity in mice with severe combined immunodeficiency. J. Immunol. 153:1687.
11. Philips, J. H., and L. L. Lanier. 1988. Dissection of the LAK phenomenon: relative contribution of peripheral blood natural killer cells and T lymphocytes to cytolysis. J. Exp. Med. 164:814.
12. Sawada, H., T. Abo, and S. Sugawara. 1988. Prerequisite for the induction of LAK cells from T lymphocytes. J. Immunol. 140:3668.
13. Rosenberg, S. A., P. S. Spiess, and R. Refreniere. 1986. A new approach to the adoptive immunotherapy of cancer with tumor-infiltrating lymphocytes. Science 233:1318.
14. Schmidt-Wolf, I. G. H., R. S. Negrin, H. Kiem, K. G. Blume, and I. L. Weisman. 1991. Use of a SCID mouse/human lymphoma model to evaluate cytokine-induced killer cells with potent antitumor cell activity. J. Exp. Med. 174:139.
15. Testa, U., A. Care, E. Montesoro, C. Fossati, G. Giamella, R. Masciulli, M. Fagioli. D. Bulgarini, D. Habetswallner, G. Isacchi, P. G. Pelicci, and C. Peschle. 1990. Interleukin-2-dependent long-term cultures of low-density lymphocytes allow the proliferation of lymphokine-activated killer cells with natural killer. Tiα/δ or TNK phenotype. Cancer Immunol. Immunother. 31:11.
16. + T lymphocytes, and NK cells. J. Immunol. 149:3495.
17. Robertson, M. J., R. J. Soiffer, S. F. Wolf, T. J. Manley, C. Donahue, D. Young, S. H. Herrman, and J. Ritz. 1992. Response of human natural killer (NK) cells to NK cell stimulatory factor (NKSF): cytolytic activity and proliferation of NK cells are differentially regulated by NKSF. J. Exp. Med. 175:779.
18. Gately, M. K., A. G. Wolizky, P. M. Quinn, and R. Chizzonite. 1992. Regulation of human cytolytic lymphocyte responses by interleukin-12. Cell. Immunol. 143:127.
19. + αβ T cells in the lung of euthymic and athymic mice. Immunology 88:82.
20. + αβ T cells activated by IL-12 as a major effector in inhibition of experimental tumor metastasis. J. Immunol. 156:3366.
21. + T cells which increase at tumor sites in patients with colorectal cancer. Clin. Exp. Immunol. 102:159.
22. + cells. J. Immunol. 145:3209.
23. + surface phenotype and a T helper type 1 profile of cytokine secretion in the liver of patients chronically infected with hepatitis B virus. J. Immunol. 152:3074.
24. Seki, S., T. Abo, T. Masuda, T. Ohteki, A. Kanno, K. Takeda, H. Rikiishi, H. Nagura, and K. Kumagai. 1990. Identification of activated T cell receptor γδ T lymphocytes in the liver of tumor-bearing hosts. J. Clin. Invest. 86:409.
25. + T cells in patients with malignancy. Clin. Exp. Immunol. 97:522.
26. + T cells are present within a population of intermediate TCR cells. J. Immunol. 155:2972.
27. Lanier, L. L., A. M, Le, C. I. Civin, M. R. Loken, and J. H. Phillips. 1986. The relationship of CD 16 (Leu 11) and Leu 19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes. J. Immunol. 136:4480.
28. Makino, Y., H. Koseki, Y. Adachi, T. Asaka, K.-I. Tsuchida, and M. Taniguchi. 1994. Extrathymic diferentiation of a T cell bearing invariant Vα14Jα281 TCR. Int. Rev. Immunol. 11:31.
29. - α/β T cells demonstrates preferential use of several Vβ genes and an invariant TCR α chain. J. Exp. Med. 178:1.
30. - T cells in mice and humans. J. Exp. Med. 180:1097.
31. - cells. J. Exp. Med. 180:1171.
32. + lymphocytes. J. Immunol. 146:3242.
33. Smyth, M. J., Y. Norishima, and J. R. Ortaldo. 1992. Multiple cytolytic mechanism displayed by activated peripheral blood T cell subsets. J. Immunol. 148:55.
34. + cytolytic T cells kill antigen-pulsed T cells by induction of apoptosis. J. Immunol. 150:4856.