Targeting regulatory factors to intranuclear replication sites

Critical Reviews in Eukaryotic Gene Expression

Volumn 10, Issue 2, 2000, Pages 127-133

  Leonhardt, H ^a   Sporbert, A ^a   Cardoso, M C ^a  

^a FRANZ VOLHARD CLINIC   (Germany)

Author keywords

Chromatin structure; DNA replication; Functional organization of the nucleus; Protein targeting; Random diffusion

Indexed keywords

CYCLIN A; CYCLIN DEPENDENT KINASE; CYCLINE; DNA; DNA DIRECTED DNA POLYMERASE ALPHA; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN SERINE THREONINE KINASE; RNA; SINGLE STRANDED DNA;

CHROMATIN STRUCTURE; DNA BINDING; DNA METHYLATION; DNA PROTEIN COMPLEX; DNA REPLICATION; DNA SYNTHESIS; EUKARYOTE; NONHUMAN; PRIORITY JOURNAL; REVIEW;

EUKARYOTA; MAMMALIA;

EID: 0033757996     PISSN: 10454403     EISSN: None     Source Type: Journal    
DOI: 10.1615/critreveukargeneexpr.v10.i2.20     Document Type: Review

References (34)

1. Nuclear protein matrix: Association with newly synthesized DNA
2. The nuclear matrix: A structural milieu for genomic function
3. Existence of two populations of cyclin/proliferating cell nuclear antigen during the cell cycle: Association with DNA replication sites
4. Mapping and use of a sequence that targets DNA ligase I to sites of DNA replication in vivo
5. Protein targeting to subnuclear higher order structures: A new level of regulation and coordination of nuclear processes
6. Reversal of terminal differentiation and control of DNA replication: Cyclin A and Cdk2 specifically localize at subnuclear sites of DNA replication
7. Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1
8. Stability and nuclear distribution of mammalian replication protein A heterotrimeric complex
9. Replication timing of genes and middle repetitive sequences
10. Visualization of replication factories attached to nucleoskeleton
11. The structural basis of nuclear function
12. The timing of the formation and usage of replicase clusters in S-phase nuclei of human diploid fibroblasts
13. In vitro mutagenesis and functional expression in Escherichia coli of a cDNA encoding the catalytic domain of human DNA ligase I
14. Chromatin assembly factor 1 (CAF-1) colocalizes with replication foci in HeLa cell nuclei
15. Targeting and association of proteins with functional domains in the nucleus: The insoluble solution
16. A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei
17. Intranuclear targeting of DNA replication factors
18. Dynamics of DNA replication factories in living cells
19. Multiple domains are involved in the targeting of the mouse DNA methyltransferase to the DNA replication foci
20. Structure and function of the mouse DNA methyltransferase gene: Dnmt1 shows a tripartite structure
21. The dynamics of a pre-mRNA splicing factor in living cells
22. Dynamic properties of nuclear lamins: Lamin B is associated with sites of DNA replication
23. DNA ligase I is recruited to sites of DNA replication by an interaction with proliferating cell nuclear antigen: Identification of a common targeting mechanism for the assembly of replication factories
24. The N-terminal domain of human DNA ligase I contains the nuclear localization signal and directs the enzyme to sites of DNA replication
25. Structural organizations of replicon domains during DNA synthetic phase in the mammalian nucleus
26. Post-replicative base excision repair in replication loci
27. High mobility of proteins in the mammalian cell nucleus
28. Replication-dependent marking of DNA by PCNA facilitates CAF-1-coupled inheritance of chromatin
29. The expression of poly(ADP-ribose) polymerase during differentiation-linked DNA replication reveals that it is a component of the multiprotein DNA replication complex
30. Localization of cyclin A at the sites of cellular DNA replication
31. PCNA binding proteins
32. Nuclear domains and the nuclear matrix
33. Fen1 expression: A novel marker for cell proliferation
34. Monoclonal antibody analysis of the proliferating cell nuclear antigen (PCNA). Structural conservation and the detection of a nucleolar form